Article: Alcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study

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TitleAlcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study
AuthorsJiang, CQ
Xu, L
Lam, TH
Thomas, GN
Zhang, WS
Cheng, KK
Schooling, CM
KeywordsAlcohol
Aortic Arch Calcification
Atherosclerosis
Chinese
Older People
Issue Date2013
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
CitationInternational Journal Of Cardiology, 2013, v. 164 n. 3, p. 349-354 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.ijcard.2011.07.046
AbstractObjective: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. Methods: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. Results: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR) = 1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank >5 times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (> 5/week) or excessively having more serious AAC (P for trend = 0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. Conclusion: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. © 2011 Elsevier Ireland Ltd. All rights reserved.
ISSN0167-5273
2011 Impact Factor: 7.078
2011 SCImago Journal Rankings: 0.144
DOIhttp://dx.doi.org/10.1016/j.ijcard.2011.07.046
DC Field
Value
dc.contributor.authorJiang, CQ
dc.contributor.authorXu, L
dc.contributor.authorLam, TH
dc.contributor.authorThomas, GN
dc.contributor.authorZhang, WS
dc.contributor.authorCheng, KK
dc.contributor.authorSchooling, CM
dc.date.accessioned2012-06-26T06:27:48Z
dc.date.available2012-06-26T06:27:48Z
dc.date.issued2013
dc.description.abstractObjective: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. Methods: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. Results: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR) = 1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank >5 times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (> 5/week) or excessively having more serious AAC (P for trend = 0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. Conclusion: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. © 2011 Elsevier Ireland Ltd. All rights reserved.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationInternational Journal Of Cardiology, 2013, v. 164 n. 3, p. 349-354 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.ijcard.2011.07.046
dc.identifier.doihttp://dx.doi.org/10.1016/j.ijcard.2011.07.046
dc.identifier.issn0167-5273
2011 Impact Factor: 7.078
2011 SCImago Journal Rankings: 0.144
dc.identifier.scopuseid_2-s2.0-84875409620
dc.identifier.urihttp://hdl.handle.net/10722/151747
dc.languageeng
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
dc.publisher.placeIreland
dc.relation.ispartofInternational Journal of Cardiology
dc.subjectAlcohol
dc.subjectAortic Arch Calcification
dc.subjectAtherosclerosis
dc.subjectChinese
dc.subjectOlder People
dc.titleAlcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong
  2. University of Birmingham
  3. Guangzhou No. 12 Hospital