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Article: Alcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study
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TitleAlcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study
 
AuthorsJiang, CQ3
Xu, L1 3
Lam, TH1
Thomas, GN2
Zhang, WS3
Cheng, KK2
Schooling, CM1
 
KeywordsAlcohol
Aortic Arch Calcification
Atherosclerosis
Chinese
Older People
 
Issue Date2013
 
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
 
CitationInternational Journal Of Cardiology, 2013, v. 164 n. 3, p. 349-354 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.ijcard.2011.07.046
 
AbstractObjective: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. Methods: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. Results: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR) = 1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank >5 times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (> 5/week) or excessively having more serious AAC (P for trend = 0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. Conclusion: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. © 2011 Elsevier Ireland Ltd. All rights reserved.
 
ISSN0167-5273
2013 Impact Factor: 6.175
2013 SCImago Journal Rankings: 0.930
 
DOIhttp://dx.doi.org/10.1016/j.ijcard.2011.07.046
 
ISI Accession Number IDWOS:000316599700024
 
DC FieldValue
dc.contributor.authorJiang, CQ
 
dc.contributor.authorXu, L
 
dc.contributor.authorLam, TH
 
dc.contributor.authorThomas, GN
 
dc.contributor.authorZhang, WS
 
dc.contributor.authorCheng, KK
 
dc.contributor.authorSchooling, CM
 
dc.date.accessioned2012-06-26T06:27:48Z
 
dc.date.available2012-06-26T06:27:48Z
 
dc.date.issued2013
 
dc.description.abstractObjective: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. Methods: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. Results: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR) = 1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank >5 times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (> 5/week) or excessively having more serious AAC (P for trend = 0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. Conclusion: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. © 2011 Elsevier Ireland Ltd. All rights reserved.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationInternational Journal Of Cardiology, 2013, v. 164 n. 3, p. 349-354 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.ijcard.2011.07.046
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.ijcard.2011.07.046
 
dc.identifier.epage354
 
dc.identifier.hkuros214092
 
dc.identifier.isiWOS:000316599700024
 
dc.identifier.issn0167-5273
2013 Impact Factor: 6.175
2013 SCImago Journal Rankings: 0.930
 
dc.identifier.issue3
 
dc.identifier.pmid21813196
 
dc.identifier.scopuseid_2-s2.0-84884211989
 
dc.identifier.spage349
 
dc.identifier.urihttp://hdl.handle.net/10722/151747
 
dc.identifier.volume164
 
dc.languageeng
 
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
 
dc.publisher.placeIreland
 
dc.relation.ispartofInternational Journal of Cardiology
 
dc.subjectAlcohol
 
dc.subjectAortic Arch Calcification
 
dc.subjectAtherosclerosis
 
dc.subjectChinese
 
dc.subjectOlder People
 
dc.titleAlcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study
 
dc.typeArticle
 
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<item><contributor.author>Jiang, CQ</contributor.author>
<contributor.author>Xu, L</contributor.author>
<contributor.author>Lam, TH</contributor.author>
<contributor.author>Thomas, GN</contributor.author>
<contributor.author>Zhang, WS</contributor.author>
<contributor.author>Cheng, KK</contributor.author>
<contributor.author>Schooling, CM</contributor.author>
<date.accessioned>2012-06-26T06:27:48Z</date.accessioned>
<date.available>2012-06-26T06:27:48Z</date.available>
<date.issued>2013</date.issued>
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<identifier.issn>0167-5273</identifier.issn>
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<description.abstract>Objective: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. Methods: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. Results: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR) = 1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank &gt;5 times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (&gt; 5/week) or excessively having more serious AAC (P for trend = 0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. Conclusion: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. &#169; 2011 Elsevier Ireland Ltd. All rights reserved.</description.abstract>
<language>eng</language>
<publisher>Elsevier Ireland Ltd. The Journal&apos;s web site is located at http://www.elsevier.com/locate/ijcard</publisher>
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<subject>Alcohol</subject>
<subject>Aortic Arch Calcification</subject>
<subject>Atherosclerosis</subject>
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<subject>Older People</subject>
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Author Affiliations
  1. The University of Hong Kong
  2. University of Birmingham
  3. Guangzhou No. 12 Hospital