File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Passive smoking and aortic arch calcification in older Chinese never smokers: The Guangzhou Biobank Cohort Study

TitlePassive smoking and aortic arch calcification in older Chinese never smokers: The Guangzhou Biobank Cohort Study
Authors
Issue Date2011
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcard
Citation
International Journal Of Cardiology, 2011, v. 148 n. 2, p. 189-193 How to Cite?
Abstract
Objective: To study whether passive smoking is a risk factor for aortic arch calcification (AAC) among never smokers. Background: We have previously reported that active smoking increases the risk of AAC, but the effect of passive smoking has not been reported. Methods: We used baseline data of the Phase 1 Guangzhou Biobank Cohort Study (GBCS). 7702 older Chinese never smokers from the Phase 1 GBCS were included. Information on passive smoking and potential confounders were collected by standardized interviews and laboratory assays. AAC was diagnosed from chest X-ray by two experienced radiologists. Unconditional logistic regression was used to estimate odds ratios of AAC for passive smoking with adjustment for potential confounders. Results: In women, the risk for aortic arch calcification (AAC) increased significantly with increasing duration of adulthood passive smoking exposure at home, at work and total duration of adulthood home and work exposure [adjusted odds ratio 1.24 (95% confidence interval 1.09-1.41) for high level of total exposure] (P for trend from 0.012 to 0.001). For passive smoking at home, at work and total exposure, significant trends of increasing severity of AAC with increasing duration of exposure were observed in men and women combined (P for trend from 0.05 to 0.002). Conclusion: Passive smoking is a risk factor for aortic arch calcification. Studies of passive smoking and AAC, especially in developing countries can generate important local evidence to raise awareness and to support public health measures to protect non-smokers from second-hand smoke. © 2009 Elsevier Ireland Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/151732
ISSN
2013 Impact Factor: 6.175
2013 SCImago Journal Rankings: 0.930
ISI Accession Number ID
Funding AgencyGrant Number
University of Hong Kong Foundation for Educational Development and Research, Hong Kong
Guangzhou Public Health Bureau, Guangzhou, China
Guangzhou Science and Technology Bureau, Guangzhou, China
University of Birmingham, UK
Funding Information:

The study is funded by The University of Hong Kong Foundation for Educational Development and Research, Hong Kong; the Guangzhou Public Health Bureau and the Guangzhou Science and Technology Bureau, Guangzhou, China; and The University of Birmingham, UK. The Guangzhou Biobank Cohort Study investigators include: the Guangzhou No. 12 Hospital: X Q Lao, W S Zhang, M Cao, T Zhu, B Liu, C Q Jiang (Co-PI); The University of Hong Kong: G N Thomas, C M Schooling, S M McGhee, R F Fielding, G M Leung, T H Lam (Co-PI); The University of Birmingham: P Adab, M Zeegers, K K Cheng (Co-PI).

References

 

DC FieldValueLanguage
dc.contributor.authorXu, Len_US
dc.contributor.authorJiang, CQen_US
dc.contributor.authorLam, THen_US
dc.contributor.authorThomas, GNen_US
dc.contributor.authorZhang, WSen_US
dc.contributor.authorCheng, KKen_US
dc.date.accessioned2012-06-26T06:27:22Z-
dc.date.available2012-06-26T06:27:22Z-
dc.date.issued2011en_US
dc.identifier.citationInternational Journal Of Cardiology, 2011, v. 148 n. 2, p. 189-193en_US
dc.identifier.issn0167-5273en_US
dc.identifier.urihttp://hdl.handle.net/10722/151732-
dc.description.abstractObjective: To study whether passive smoking is a risk factor for aortic arch calcification (AAC) among never smokers. Background: We have previously reported that active smoking increases the risk of AAC, but the effect of passive smoking has not been reported. Methods: We used baseline data of the Phase 1 Guangzhou Biobank Cohort Study (GBCS). 7702 older Chinese never smokers from the Phase 1 GBCS were included. Information on passive smoking and potential confounders were collected by standardized interviews and laboratory assays. AAC was diagnosed from chest X-ray by two experienced radiologists. Unconditional logistic regression was used to estimate odds ratios of AAC for passive smoking with adjustment for potential confounders. Results: In women, the risk for aortic arch calcification (AAC) increased significantly with increasing duration of adulthood passive smoking exposure at home, at work and total duration of adulthood home and work exposure [adjusted odds ratio 1.24 (95% confidence interval 1.09-1.41) for high level of total exposure] (P for trend from 0.012 to 0.001). For passive smoking at home, at work and total exposure, significant trends of increasing severity of AAC with increasing duration of exposure were observed in men and women combined (P for trend from 0.05 to 0.002). Conclusion: Passive smoking is a risk factor for aortic arch calcification. Studies of passive smoking and AAC, especially in developing countries can generate important local evidence to raise awareness and to support public health measures to protect non-smokers from second-hand smoke. © 2009 Elsevier Ireland Ltd.en_US
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ijcarden_US
dc.relation.ispartofInternational Journal of Cardiologyen_US
dc.subject.meshAge Distributionen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshAorta, Thoracic - Pathologyen_US
dc.subject.meshAortic Arch Syndromes - Ethnology - Pathologyen_US
dc.subject.meshAsian Continental Ancestry Group - Statistics & Numerical Dataen_US
dc.subject.meshCalcinosis - Ethnology - Pathologyen_US
dc.subject.meshChina - Epidemiologyen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSex Distributionen_US
dc.subject.meshTobacco Smoke Pollution - Adverse Effects - Statistics & Numerical Dataen_US
dc.titlePassive smoking and aortic arch calcification in older Chinese never smokers: The Guangzhou Biobank Cohort Studyen_US
dc.typeArticleen_US
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_US
dc.identifier.authorityLam, TH=rp00326en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ijcard.2009.11.001en_US
dc.identifier.pmid19945183en_US
dc.identifier.scopuseid_2-s2.0-79953249460en_US
dc.identifier.hkuros228922-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79953249460&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume148en_US
dc.identifier.issue2en_US
dc.identifier.spage189en_US
dc.identifier.epage193en_US
dc.identifier.isiWOS:000288787000018-
dc.publisher.placeIrelanden_US
dc.identifier.scopusauthoridXu, L=7404744449en_US
dc.identifier.scopusauthoridJiang, CQ=10639500500en_US
dc.identifier.scopusauthoridLam, TH=7202522876en_US
dc.identifier.scopusauthoridThomas, GN=35465269900en_US
dc.identifier.scopusauthoridZhang, WS=35180743500en_US
dc.identifier.scopusauthoridCheng, KK=7402997800en_US
dc.identifier.citeulike6255516-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats