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Article: Smoking, diabetes and cardiovascular diseases in men in the Asia Pacific region.

TitleSmoking, diabetes and cardiovascular diseases in men in the Asia Pacific region.
Authors
Issue Date2009
Citation
Journal Of Diabetes, 2009, v. 1 n. 3, p. 173-181 How to Cite?
AbstractTo assess whether there is a statistical interaction between smoking and diabetes that is related to the risk of cardiovascular disease (CVD) in men in the Asia Pacific region. An individual participant data meta-analysis was conducted on 34 cohort studies, involving 16 492 participants with diabetes (47.4% smokers) and 188 897 without (47.6% smokers). Hazard ratios (HR) and 95% confidence intervals (CI) were calculated for smoking (stratified by study and adjusted for age) for those with and without diabetes. In men with diabetes, the HR (95% CI) comparing current smokers with non-smokers was 1.42 (1.10-1.83) for coronary heart disease, 1.10 (0.88-1.37) for total stroke and 1.15 (0.98-1.35) for total CVD. The corresponding figures for men without diabetes were 1.47 (1.33-1.61), 1.27 (1.16-1.39) and 1.35 (1.27-1.44), respectively. There was no evidence of a statistical interaction between diabetes and current smoking, the number of cigarettes smoked per day or quitting smoking. Smoking cessation was associated with a 19% reduction in CVD risk, irrespective of diabetes status. The effects of cigarette smoking and smoking cessation are broadly similar in men with and without diabetes. In Asia, where there are high rates of smoking and a rapidly increasing prevalence of diabetes, strategies that encourage smokers to quit are likely to have huge benefits in terms of reducing the burden of CVD in men with diabetes. © 2009 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/151715
ISSN
2015 SCImago Journal Rankings: 0.762
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKengne, APen_US
dc.contributor.authorNakamura, Ken_US
dc.contributor.authorBarzi, Fen_US
dc.contributor.authorLam, THen_US
dc.contributor.authorHuxley, Ren_US
dc.contributor.authorGu, Den_US
dc.contributor.authorPatel, Aen_US
dc.contributor.authorKim, HCen_US
dc.contributor.authorWoodward, Men_US
dc.contributor.authorAsia Pacific Cohort Study Collaborationen_US
dc.date.accessioned2012-06-26T06:27:02Z-
dc.date.available2012-06-26T06:27:02Z-
dc.date.issued2009en_US
dc.identifier.citationJournal Of Diabetes, 2009, v. 1 n. 3, p. 173-181en_US
dc.identifier.issn1753-0407en_US
dc.identifier.urihttp://hdl.handle.net/10722/151715-
dc.description.abstractTo assess whether there is a statistical interaction between smoking and diabetes that is related to the risk of cardiovascular disease (CVD) in men in the Asia Pacific region. An individual participant data meta-analysis was conducted on 34 cohort studies, involving 16 492 participants with diabetes (47.4% smokers) and 188 897 without (47.6% smokers). Hazard ratios (HR) and 95% confidence intervals (CI) were calculated for smoking (stratified by study and adjusted for age) for those with and without diabetes. In men with diabetes, the HR (95% CI) comparing current smokers with non-smokers was 1.42 (1.10-1.83) for coronary heart disease, 1.10 (0.88-1.37) for total stroke and 1.15 (0.98-1.35) for total CVD. The corresponding figures for men without diabetes were 1.47 (1.33-1.61), 1.27 (1.16-1.39) and 1.35 (1.27-1.44), respectively. There was no evidence of a statistical interaction between diabetes and current smoking, the number of cigarettes smoked per day or quitting smoking. Smoking cessation was associated with a 19% reduction in CVD risk, irrespective of diabetes status. The effects of cigarette smoking and smoking cessation are broadly similar in men with and without diabetes. In Asia, where there are high rates of smoking and a rapidly increasing prevalence of diabetes, strategies that encourage smokers to quit are likely to have huge benefits in terms of reducing the burden of CVD in men with diabetes. © 2009 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd.en_US
dc.languageengen_US
dc.relation.ispartofJournal of diabetesen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAsia, Southeasternen_US
dc.subject.meshCardiovascular Diseases - Epidemiologyen_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshConfidence Intervalsen_US
dc.subject.meshCoronary Disease - Epidemiologyen_US
dc.subject.meshDiabetes Mellitus - Epidemiologyen_US
dc.subject.meshDiabetes Mellitus, Type 2 - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPacific Islandsen_US
dc.subject.meshProportional Hazards Modelsen_US
dc.subject.meshRisken_US
dc.subject.meshRisk Reduction Behavioren_US
dc.subject.meshSmoking - Epidemiologyen_US
dc.subject.meshSmoking Cessationen_US
dc.subject.meshStroke - Epidemiologyen_US
dc.subject.meshYoung Adulten_US
dc.titleSmoking, diabetes and cardiovascular diseases in men in the Asia Pacific region.en_US
dc.typeArticleen_US
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_US
dc.identifier.authorityLam, TH=rp00326en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1111/j.1753-0407.2009.00028.x-
dc.identifier.pmid20923536-
dc.identifier.scopuseid_2-s2.0-77953855021en_US
dc.identifier.hkuros183398-
dc.identifier.volume1en_US
dc.identifier.issue3en_US
dc.identifier.spage173en_US
dc.identifier.epage181en_US
dc.identifier.isiWOS:000208415100013-
dc.identifier.scopusauthoridKengne, AP=7801322838en_US
dc.identifier.scopusauthoridNakamura, K=11139298500en_US
dc.identifier.scopusauthoridBarzi, F=7003545543en_US
dc.identifier.scopusauthoridLam, TH=7202522876en_US
dc.identifier.scopusauthoridHuxley, R=6701828350en_US
dc.identifier.scopusauthoridGu, D=7202151958en_US
dc.identifier.scopusauthoridPatel, A=7403524909en_US
dc.identifier.scopusauthoridKim, HC=8540942600en_US
dc.identifier.scopusauthoridWoodward, M=7102510958en_US
dc.identifier.scopusauthoridAsia Pacific Cohort Study Collaboration=37001785400en_US

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