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Article: A prospective cohort study on the effect of occupational dust exposure and smoking on mortality

TitleA prospective cohort study on the effect of occupational dust exposure and smoking on mortality
職業接觸粉塵及吸煙對死亡影響的前瞻性隊列研究
Authors
KeywordsDust (粉塵)
Smoking (吸煙)
Mortality (死亡)
Prospective cohort study (前瞻性隊列研究)
Issue Date2002
PublisherTianjin Shi Wei Sheng Fang Bing Zhong Xin (天津市衛生防病中心). The Journal's web site is located at http://zhldwszyb.periodicals.net.cn/default.html
Citation
Chinese Journal Of Industrial Hygiene And Occupational Diseases, 2002, v. 20 n. 5, p. 365-368 How to Cite?
中華勞動衛生職業病雜誌, 2002, v. 20 n. 5, p. 365-368 How to Cite?
AbstractOBJECTIVE: To study the effect of dust exposure and smoking on mortality. METHODS: Based on the Guangzhou Occupational Health Surveillance Record System established in 1989-1992, 61,648 factory workers, aged > or = 30, occupationally exposed to dust and non-exposure to dust or any other hazardous substances(controls), were included in a prospective cohort study. RESULTS: (1) 28 were lost to follow-up. Malignant neoplasm was most common among 1,186 deaths. (2) Most subjects were male workers, aged 35 to 44, with secondary education, and married. 42.2% had ever smoked and 32.8% were ever-drinkers. (3) To compare with non-exposure, non-smoking + non-smoking and non-exposure respectively, the adjusted RR of death from all causes, malignant neoplasm and respiratory diseases were 1.24, 1.34 and 1.96 respectively for dust exposed workers(compared to control, P < 0.01), 1.16, 1.37 and 1.63 respectively for those smoking(compared to non-smoker except RR of death from respiratory diseases, P < 0.01), and 1.48, 1.85 and 3.12 respectively for those smoking and dust exposure, which were far greater than those either smoked or exposed to dust alone(P < 0.01). (4) The influence of dust exposure on death was mainly showed in occupational exposure to silica dust and wood dust. CONCLUSION: Both dust exposure and smoking may increase the mortality, and they had synergistic effect. 目的 研究接塵和吸煙對死亡的影響。方法 以 1989~ 1992年廣州市實施并建立的職工職業健康監護檔案為基礎資料 ,選年齡≥ 30歲的接塵工人和無任何粉塵及其他有害物質接觸的職工 (對照組 ) 6 16 4 8名為研究對象 ,進行前瞻性隊列研究。結果  (1)隊列失訪 2 8例 ,死亡 1186例 ,以惡性腫瘤死亡為主 ;(2 )本隊列男性多于女性 ,年齡 35~ 4 4歲居多 ,主要為工人 ,中學文化 ,已婚 ,吸煙率 4 2 .2 % ,飲酒率 32 .8% ;(3)調整相應混雜因素后 ,全死因、惡性腫瘤和呼吸系疾病死亡接塵者相對危險度 (RR)分別為 1.2 4、1.34和 1.96 ,與對照組比較 ,差異均有顯著性 (P <0 .0 1) ,吸煙者RR分別為1.16、1.37和 1.6 3,與不吸煙者比 ,前二者差異有顯著性 (P <0 .0 1) ;既接塵又吸煙者上述相應死因死亡RR分別為 1.4 8、1.85和 3.12 ,明顯高于單純接塵或單純吸煙者 ,差異有顯著性 (P <0 .0 1) ;(4)接塵對死亡的影響主要表現在職業接觸矽塵和木塵。結論 接塵與吸煙均可致死亡危險性增加 ,并存在協同作用。
Persistent Identifierhttp://hdl.handle.net/10722/151655
ISSN
2015 SCImago Journal Rankings: 0.117

 

DC FieldValueLanguage
dc.contributor.authorZhang, Wen_US
dc.contributor.authorJiang, Cen_US
dc.contributor.authorLam, THen_US
dc.contributor.authorChen, Qen_US
dc.contributor.authorHo, SYen_US
dc.contributor.authorLiu, Wen_US
dc.contributor.authorHe, Jen_US
dc.contributor.authorCao, Men_US
dc.date.accessioned2012-06-26T06:26:06Z-
dc.date.available2012-06-26T06:26:06Z-
dc.date.issued2002en_US
dc.identifier.citationChinese Journal Of Industrial Hygiene And Occupational Diseases, 2002, v. 20 n. 5, p. 365-368en_US
dc.identifier.citation中華勞動衛生職業病雜誌, 2002, v. 20 n. 5, p. 365-368-
dc.identifier.issn1001-9391en_US
dc.identifier.urihttp://hdl.handle.net/10722/151655-
dc.description.abstractOBJECTIVE: To study the effect of dust exposure and smoking on mortality. METHODS: Based on the Guangzhou Occupational Health Surveillance Record System established in 1989-1992, 61,648 factory workers, aged > or = 30, occupationally exposed to dust and non-exposure to dust or any other hazardous substances(controls), were included in a prospective cohort study. RESULTS: (1) 28 were lost to follow-up. Malignant neoplasm was most common among 1,186 deaths. (2) Most subjects were male workers, aged 35 to 44, with secondary education, and married. 42.2% had ever smoked and 32.8% were ever-drinkers. (3) To compare with non-exposure, non-smoking + non-smoking and non-exposure respectively, the adjusted RR of death from all causes, malignant neoplasm and respiratory diseases were 1.24, 1.34 and 1.96 respectively for dust exposed workers(compared to control, P < 0.01), 1.16, 1.37 and 1.63 respectively for those smoking(compared to non-smoker except RR of death from respiratory diseases, P < 0.01), and 1.48, 1.85 and 3.12 respectively for those smoking and dust exposure, which were far greater than those either smoked or exposed to dust alone(P < 0.01). (4) The influence of dust exposure on death was mainly showed in occupational exposure to silica dust and wood dust. CONCLUSION: Both dust exposure and smoking may increase the mortality, and they had synergistic effect. 目的 研究接塵和吸煙對死亡的影響。方法 以 1989~ 1992年廣州市實施并建立的職工職業健康監護檔案為基礎資料 ,選年齡≥ 30歲的接塵工人和無任何粉塵及其他有害物質接觸的職工 (對照組 ) 6 16 4 8名為研究對象 ,進行前瞻性隊列研究。結果  (1)隊列失訪 2 8例 ,死亡 1186例 ,以惡性腫瘤死亡為主 ;(2 )本隊列男性多于女性 ,年齡 35~ 4 4歲居多 ,主要為工人 ,中學文化 ,已婚 ,吸煙率 4 2 .2 % ,飲酒率 32 .8% ;(3)調整相應混雜因素后 ,全死因、惡性腫瘤和呼吸系疾病死亡接塵者相對危險度 (RR)分別為 1.2 4、1.34和 1.96 ,與對照組比較 ,差異均有顯著性 (P <0 .0 1) ,吸煙者RR分別為1.16、1.37和 1.6 3,與不吸煙者比 ,前二者差異有顯著性 (P <0 .0 1) ;既接塵又吸煙者上述相應死因死亡RR分別為 1.4 8、1.85和 3.12 ,明顯高于單純接塵或單純吸煙者 ,差異有顯著性 (P <0 .0 1) ;(4)接塵對死亡的影響主要表現在職業接觸矽塵和木塵。結論 接塵與吸煙均可致死亡危險性增加 ,并存在協同作用。en_US
dc.languagechien_US
dc.publisherTianjin Shi Wei Sheng Fang Bing Zhong Xin (天津市衛生防病中心). The Journal's web site is located at http://zhldwszyb.periodicals.net.cn/default.htmlen_US
dc.relation.ispartofChinese journal of industrial hygiene and occupational diseasesen_US
dc.relation.ispartof中華勞動衛生職業病雜誌-
dc.subjectDust (粉塵)-
dc.subjectSmoking (吸煙)-
dc.subjectMortality (死亡)-
dc.subjectProspective cohort study (前瞻性隊列研究)-
dc.subject.meshAdulten_US
dc.subject.meshCohort Studiesen_US
dc.subject.meshDusten_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshOccupational Exposure - Adverse Effectsen_US
dc.subject.meshProspective Studiesen_US
dc.subject.meshSilicon Dioxideen_US
dc.subject.meshSmoking - Mortalityen_US
dc.subject.meshWooden_US
dc.titleA prospective cohort study on the effect of occupational dust exposure and smoking on mortalityen_US
dc.title職業接觸粉塵及吸煙對死亡影響的前瞻性隊列研究-
dc.typeArticleen_US
dc.identifier.emailLam, TH:hrmrlth@hkucc.hku.hken_US
dc.identifier.authorityLam, TH=rp00326en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid14694728-
dc.identifier.scopuseid_2-s2.0-46649121532en_US
dc.identifier.hkuros75660-
dc.identifier.volume20en_US
dc.identifier.issue5en_US
dc.identifier.spage365en_US
dc.identifier.epage368en_US
dc.publisher.placeChina (中國)en_US
dc.identifier.scopusauthoridZhang, W=13410704100en_US
dc.identifier.scopusauthoridJiang, C=10639500500en_US
dc.identifier.scopusauthoridLam, TH=7202522876en_US
dc.identifier.scopusauthoridChen, Q=35602829700en_US
dc.identifier.scopusauthoridYin, HS=23500306800en_US
dc.identifier.scopusauthoridLiu, W=26643405200en_US
dc.identifier.scopusauthoridHe, J=7404983600en_US
dc.identifier.scopusauthoridCao, M=35226290200en_US
dc.customcontrol.immutablecsl 151116-

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