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Article: Serum lipids in a teenage population: Geographic, seasonal and familial factors

TitleSerum lipids in a teenage population: Geographic, seasonal and familial factors
Authors
Issue Date1981
PublisherOxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/
Citation
International Journal Of Epidemiology, 1981, v. 10 n. 2, p. 161-170 How to Cite?
AbstractThe lipid results of a cross-sectional study of cardiovascular disease risk factors in over 600 13-18 year olds drawn from general practices in contrasting areas are reported. Differences were noted between the 3 practices, including a significant variation in the blood group distribution. HDL cholesterol showed a marked variation between the 3 practices which was unlikely to be due solely to seasonal variation. Alcohol consumption though not a univariate correlate of HDL cholesterol was however a strong partial correlate, as were age, height, sexual maturation, adiposity and smoking. Using 6 factors in each sex, 13% of the interchild variance of HDL cholesterol in boys could be explained in a multiple linear regression analysis, and 8% in girls. Including the practice variation as a further independent variable increased the explanation to 18% in boys and 15% in girls. An intraclass correlation (sib-sib) of 0.36 was found for HDL cholesterol, suggesting a strong familial influence. The implications of these results are discussed, along with the difficulties of screening for hyperlipidaemia in this age group.
Persistent Identifierhttp://hdl.handle.net/10722/151422
ISSN
2015 Impact Factor: 7.522
2015 SCImago Journal Rankings: 4.381
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorOrchard, TJen_US
dc.contributor.authorRodgers, Men_US
dc.contributor.authorHedley, AJen_US
dc.contributor.authorMitchell, JRAen_US
dc.date.accessioned2012-06-26T06:23:10Z-
dc.date.available2012-06-26T06:23:10Z-
dc.date.issued1981en_US
dc.identifier.citationInternational Journal Of Epidemiology, 1981, v. 10 n. 2, p. 161-170en_US
dc.identifier.issn0300-5771en_US
dc.identifier.urihttp://hdl.handle.net/10722/151422-
dc.description.abstractThe lipid results of a cross-sectional study of cardiovascular disease risk factors in over 600 13-18 year olds drawn from general practices in contrasting areas are reported. Differences were noted between the 3 practices, including a significant variation in the blood group distribution. HDL cholesterol showed a marked variation between the 3 practices which was unlikely to be due solely to seasonal variation. Alcohol consumption though not a univariate correlate of HDL cholesterol was however a strong partial correlate, as were age, height, sexual maturation, adiposity and smoking. Using 6 factors in each sex, 13% of the interchild variance of HDL cholesterol in boys could be explained in a multiple linear regression analysis, and 8% in girls. Including the practice variation as a further independent variable increased the explanation to 18% in boys and 15% in girls. An intraclass correlation (sib-sib) of 0.36 was found for HDL cholesterol, suggesting a strong familial influence. The implications of these results are discussed, along with the difficulties of screening for hyperlipidaemia in this age group.en_US
dc.languageengen_US
dc.publisherOxford University Press. The Journal's web site is located at http://ije.oxfordjournals.org/en_US
dc.relation.ispartofInternational Journal of Epidemiologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAge Factorsen_US
dc.subject.meshCholesterol - Blooden_US
dc.subject.meshCholesterol, Hdlen_US
dc.subject.meshDieten_US
dc.subject.meshEnglanden_US
dc.subject.meshFemaleen_US
dc.subject.meshGeneticsen_US
dc.subject.meshGrowthen_US
dc.subject.meshHumansen_US
dc.subject.meshLipids - Blooden_US
dc.subject.meshLipoproteins, Hdl - Blooden_US
dc.subject.meshMaleen_US
dc.subject.meshRisken_US
dc.subject.meshSeasonsen_US
dc.subject.meshSex Factorsen_US
dc.subject.meshSexual Maturationen_US
dc.subject.meshTime Factorsen_US
dc.titleSerum lipids in a teenage population: Geographic, seasonal and familial factorsen_US
dc.typeArticleen_US
dc.identifier.emailHedley, AJ:hrmrajh@hkucc.hku.hken_US
dc.identifier.authorityHedley, AJ=rp00357en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid7287276-
dc.identifier.scopuseid_2-s2.0-0019410892en_US
dc.identifier.volume10en_US
dc.identifier.issue2en_US
dc.identifier.spage161en_US
dc.identifier.epage170en_US
dc.identifier.isiWOS:A1981MF02400007-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridOrchard, TJ=7102290820en_US
dc.identifier.scopusauthoridRodgers, M=7102573049en_US
dc.identifier.scopusauthoridHedley, AJ=7102584095en_US
dc.identifier.scopusauthoridMitchell, JRA=24302858200en_US

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