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Article: Thyroid function in normal subjects in Iceland and Northeast Scotland

TitleThyroid function in normal subjects in Iceland and Northeast Scotland
Authors
Issue Date1977
PublisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664
Citation
Clinical Endocrinology, 1977, v. 7 n. 5, p. 377-382 How to Cite?
AbstractA comparative study was made of thyroid function in samples of 'well'subjects, from separate geographical areas with dissimilar dietary iodine levels. In the area with the higher iodine level, Iceland, the prevalence of positive thyroid antibody tests and serum thyrotrophin levels were lower, while the capacity of the thyroid to respond to exogenous thyrotrophin was higher than in NE Scotland, an area with lower iodine levels. In contrast the prevalence of positive tests for another organ specific antibody, gastric parietal cell antibody, was higher in Iceland. These observations are consistent with the reported differences in the incidence rates for thyrotoxicosis and gastric carcinoma in the areas studied. The results are in agreement with our findings in two groups of post-thyroidectomy patients from the same populations. This study provides support for the view that differences in the prevalence of constitutional and environmental factors in different populations contribute to the variation in reported outcome of treatment for thyroid disease.
Persistent Identifierhttp://hdl.handle.net/10722/151411
ISSN
2015 Impact Factor: 3.487
2015 SCImago Journal Rankings: 1.314
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHedley, AJen_US
dc.contributor.authorThjodleifsson, Ben_US
dc.contributor.authorDonald, Den_US
dc.date.accessioned2012-06-26T06:22:54Z-
dc.date.available2012-06-26T06:22:54Z-
dc.date.issued1977en_US
dc.identifier.citationClinical Endocrinology, 1977, v. 7 n. 5, p. 377-382en_US
dc.identifier.issn0300-0664en_US
dc.identifier.urihttp://hdl.handle.net/10722/151411-
dc.description.abstractA comparative study was made of thyroid function in samples of 'well'subjects, from separate geographical areas with dissimilar dietary iodine levels. In the area with the higher iodine level, Iceland, the prevalence of positive thyroid antibody tests and serum thyrotrophin levels were lower, while the capacity of the thyroid to respond to exogenous thyrotrophin was higher than in NE Scotland, an area with lower iodine levels. In contrast the prevalence of positive tests for another organ specific antibody, gastric parietal cell antibody, was higher in Iceland. These observations are consistent with the reported differences in the incidence rates for thyrotoxicosis and gastric carcinoma in the areas studied. The results are in agreement with our findings in two groups of post-thyroidectomy patients from the same populations. This study provides support for the view that differences in the prevalence of constitutional and environmental factors in different populations contribute to the variation in reported outcome of treatment for thyroid disease.en_US
dc.languageengen_US
dc.publisherWiley-Blackwell Publishing Ltd.. The Journal's web site is located at http://www.wiley.com/bw/journal.asp?ref=0300-0664en_US
dc.relation.ispartofClinical Endocrinologyen_US
dc.subject.meshAutoantibodies - Analysisen_US
dc.subject.meshDieten_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIcelanden_US
dc.subject.meshScotlanden_US
dc.subject.meshStomach - Immunologyen_US
dc.subject.meshThyroid Function Testsen_US
dc.subject.meshThyroid Gland - Immunology - Physiologyen_US
dc.subject.meshThyrotropin - Blooden_US
dc.titleThyroid function in normal subjects in Iceland and Northeast Scotlanden_US
dc.typeArticleen_US
dc.identifier.emailHedley, AJ:hrmrajh@hkucc.hku.hken_US
dc.identifier.authorityHedley, AJ=rp00357en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid589803-
dc.identifier.scopuseid_2-s2.0-0017688775en_US
dc.identifier.volume7en_US
dc.identifier.issue5en_US
dc.identifier.spage377en_US
dc.identifier.epage382en_US
dc.identifier.isiWOS:A1977EA64800003-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridHedley, AJ=7102584095en_US
dc.identifier.scopusauthoridThjodleifsson, B=7004491281en_US
dc.identifier.scopusauthoridDonald, D=7005415258en_US

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