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Article: Correlation of measurements from diffusion weighted MR imaging and FDG PET/CT in GIST patients: ADC versus SUV

TitleCorrelation of measurements from diffusion weighted MR imaging and FDG PET/CT in GIST patients: ADC versus SUV
Authors
KeywordsADC
Diffusion magnetic resonance imaging
GIST
PET/CT
SUV
Issue Date2012
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejrad
Citation
European Journal Of Radiology, 2012, v. 81 n. 9, p. 2122-2126 How to Cite?
AbstractPurpose: We investigated the correlation relationship between ADCs measured by MRI and SUVs measured by PET/CT of lesions on GIST (gastrointestinal stromal tumor) patients to verify if MR is able to replace or serve as an alternative to PET/CT in GIST staging and treatment monitoring. Materials and methods: Between September 2010 and January 2011, five patients with histologically proven metastatic GIST in Queen Mary Hospital, Hong Kong were enrolled into our study. All patients underwent both MRI and PET/CT scans at prognosis. Pearson's correlations of twenty-nine lesions were conducted between 5 pairs of ADCs and SUVs values. Results: Lesions in the liver, peritoneum or bowel loops were found by PET/CT and no extra-abdominal lesion was identified. All twenty-nine lesions are identifiable by MRI with sensitivity of 100%. Significant inverse correlation were found between ADC mean and SUV mean (P = 0.006), ADC mean and SUV max (P = 0.010), ADC min and SUV max (P = 0.014), ADC min and SUV mean (P = 0.026), rADC min and rSUV max (P = 0.047). Conclusion: DWI is comparable to PET/CT in visually detecting the GIST lesions' location. Significant inverse correlations were found between ADCs from DWIBS and SUVs from PET/CT on data of GIST patients. This finding demonstrates that DWI is potentially capable of offering similar information for diagnosis and treatment response evaluating in GIST's patients as PET/CT does. Furthermore, ADC min, which is determined by single pixel, is not as reliable as ADC mean, which is weighted average value of the whole lesion volume. © 2011 Elsevier Ireland Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/150922
ISSN
2015 Impact Factor: 2.593
2015 SCImago Journal Rankings: 1.166
References

 

DC FieldValueLanguage
dc.contributor.authorWong, CSen_HK
dc.contributor.authorGong, Nen_HK
dc.contributor.authorChu, YCen_HK
dc.contributor.authorAnthony, MPen_HK
dc.contributor.authorChan, Qen_HK
dc.contributor.authorLee, HFen_HK
dc.contributor.authorChu, KMen_HK
dc.contributor.authorKhong, PLen_HK
dc.date.accessioned2012-06-26T06:14:28Z-
dc.date.available2012-06-26T06:14:28Z-
dc.date.issued2012en_HK
dc.identifier.citationEuropean Journal Of Radiology, 2012, v. 81 n. 9, p. 2122-2126en_HK
dc.identifier.issn0720-048Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/150922-
dc.description.abstractPurpose: We investigated the correlation relationship between ADCs measured by MRI and SUVs measured by PET/CT of lesions on GIST (gastrointestinal stromal tumor) patients to verify if MR is able to replace or serve as an alternative to PET/CT in GIST staging and treatment monitoring. Materials and methods: Between September 2010 and January 2011, five patients with histologically proven metastatic GIST in Queen Mary Hospital, Hong Kong were enrolled into our study. All patients underwent both MRI and PET/CT scans at prognosis. Pearson's correlations of twenty-nine lesions were conducted between 5 pairs of ADCs and SUVs values. Results: Lesions in the liver, peritoneum or bowel loops were found by PET/CT and no extra-abdominal lesion was identified. All twenty-nine lesions are identifiable by MRI with sensitivity of 100%. Significant inverse correlation were found between ADC mean and SUV mean (P = 0.006), ADC mean and SUV max (P = 0.010), ADC min and SUV max (P = 0.014), ADC min and SUV mean (P = 0.026), rADC min and rSUV max (P = 0.047). Conclusion: DWI is comparable to PET/CT in visually detecting the GIST lesions' location. Significant inverse correlations were found between ADCs from DWIBS and SUVs from PET/CT on data of GIST patients. This finding demonstrates that DWI is potentially capable of offering similar information for diagnosis and treatment response evaluating in GIST's patients as PET/CT does. Furthermore, ADC min, which is determined by single pixel, is not as reliable as ADC mean, which is weighted average value of the whole lesion volume. © 2011 Elsevier Ireland Ltd.en_HK
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/ejraden_HK
dc.relation.ispartofEuropean Journal of Radiologyen_HK
dc.subjectADCen_HK
dc.subjectDiffusion magnetic resonance imagingen_HK
dc.subjectGISTen_HK
dc.subjectPET/CTen_HK
dc.subjectSUVen_HK
dc.titleCorrelation of measurements from diffusion weighted MR imaging and FDG PET/CT in GIST patients: ADC versus SUVen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, CS: drcswong@hku.hken_HK
dc.identifier.emailAnthony, MP: anthonym@hku.hken_HK
dc.identifier.emailLee, HF: vhflee@hku.hken_HK
dc.identifier.emailChu, KM: chukm@hkucc.hku.hken_HK
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_HK
dc.identifier.authorityWong, CS=rp01391en_HK
dc.identifier.authorityAnthony, MP=rp01302en_HK
dc.identifier.authorityLee, HF=rp00264en_HK
dc.identifier.authorityChu, KM=rp00435en_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.ejrad.2011.09.003en_HK
dc.identifier.pmid21955604-
dc.identifier.scopuseid_2-s2.0-84864656279en_HK
dc.identifier.hkuros206330-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84864656279&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume81en_HK
dc.identifier.issue9en_HK
dc.identifier.spage2122en_HK
dc.identifier.epage2126en_HK
dc.identifier.eissn1872-7727-
dc.publisher.placeIrelanden_HK
dc.identifier.scopusauthoridWong, CS=24605454100en_HK
dc.identifier.scopusauthoridGong, N=49663223200en_HK
dc.identifier.scopusauthoridChu, YC=7403050830en_HK
dc.identifier.scopusauthoridAnthony, MP=35270974300en_HK
dc.identifier.scopusauthoridChan, Q=6602497305en_HK
dc.identifier.scopusauthoridLee, HF=14035860900en_HK
dc.identifier.scopusauthoridChu, KM=7402453538en_HK
dc.identifier.scopusauthoridKhong, PL=7006693233en_HK
dc.identifier.citeulike9842145-

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