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Article: Establishment of cell lines from a primary hepatocellular carcinoma and its metastatis

TitleEstablishment of cell lines from a primary hepatocellular carcinoma and its metastatis
Authors
Issue Date2004
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 2004, v. 148 n. 1, p. 80-84 How to Cite?
AbstractHepatocellular carcinoma (HCC) is one of the most common malignancies in the world with a very poor prognosis that has been associated with tumor metastasis. The molecular mechanism of HCC metastasis is still unclear. In this study, we established cell lines from a primary tumor (H2-P) and its metastatis (H2-M). G-banding karyotyping, comparative genomic hybridization, and fluorescence in situ hybridization were applied to study these two cell lines and the results demonstrated that they are of the same origin. These cell lines provide a very useful tool to identify genetic alterations associated with HCC metastasis. © 2004 Elsevier Inc. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/150861
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorHu, Len_US
dc.contributor.authorWen, JMen_US
dc.contributor.authorSham, JSTen_US
dc.contributor.authorWang, Wen_US
dc.contributor.authorXie, Den_US
dc.contributor.authorTjia, WMen_US
dc.contributor.authorHuang, JFen_US
dc.contributor.authorZhang, Men_US
dc.contributor.authorZeng, WFen_US
dc.contributor.authorGuan, XYen_US
dc.date.accessioned2012-06-26T06:12:50Z-
dc.date.available2012-06-26T06:12:50Z-
dc.date.issued2004en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 2004, v. 148 n. 1, p. 80-84en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/150861-
dc.description.abstractHepatocellular carcinoma (HCC) is one of the most common malignancies in the world with a very poor prognosis that has been associated with tumor metastasis. The molecular mechanism of HCC metastasis is still unclear. In this study, we established cell lines from a primary tumor (H2-P) and its metastatis (H2-M). G-banding karyotyping, comparative genomic hybridization, and fluorescence in situ hybridization were applied to study these two cell lines and the results demonstrated that they are of the same origin. These cell lines provide a very useful tool to identify genetic alterations associated with HCC metastasis. © 2004 Elsevier Inc. All rights reserved.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.subject.meshAdulten_US
dc.subject.meshCarcinoma, Hepatocellular - Genetics - Pathology - Secondaryen_US
dc.subject.meshChromosome Aberrationsen_US
dc.subject.meshChromosome Bandingen_US
dc.subject.meshHumansen_US
dc.subject.meshIn Situ Hybridization, Fluorescenceen_US
dc.subject.meshLiver Neoplasms - Genetics - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshNucleic Acid Hybridizationen_US
dc.subject.meshTumor Cells, Cultureden_US
dc.titleEstablishment of cell lines from a primary hepatocellular carcinoma and its metastatisen_US
dc.typeArticleen_US
dc.identifier.emailGuan, XY:xyguan@hkucc.hku.hken_US
dc.identifier.authorityGuan, XY=rp00454en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(03)00206-1en_US
dc.identifier.pmid14697646-
dc.identifier.scopuseid_2-s2.0-9144264832en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-9144264832&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume148en_US
dc.identifier.issue1en_US
dc.identifier.spage80en_US
dc.identifier.epage84en_US
dc.identifier.isiWOS:000187804800013-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridHu, L=34770075600en_US
dc.identifier.scopusauthoridWen, JM=7402701931en_US
dc.identifier.scopusauthoridSham, JST=7101655565en_US
dc.identifier.scopusauthoridWang, W=36488756900en_US
dc.identifier.scopusauthoridXie, D=35070710200en_US
dc.identifier.scopusauthoridTjia, WM=8631854600en_US
dc.identifier.scopusauthoridHuang, JF=7407192439en_US
dc.identifier.scopusauthoridZhang, M=16302423500en_US
dc.identifier.scopusauthoridZeng, WF=8338623800en_US
dc.identifier.scopusauthoridGuan, XY=7201463221en_US

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