File Download
 
Links for fulltext
(May Require Subscription)
 
Supplementary

Article: Role of translationally controlled tumor protein in cancer progression
  • Basic View
  • Metadata View
  • XML View
TitleRole of translationally controlled tumor protein in cancer progression
 
AuthorsChan, THM1 3
Chen, L1 3
Guan, XY1 3 2
 
Issue Date2012
 
CitationBiochemistry Research International, 2012 [How to Cite?]
DOI: http://dx.doi.org/10.1155/2012/369384
 
AbstractTranslationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein in all eukaryoteshighlighting its important functions in the cell. Previous studies revealed that TCTP is implicated in many biological processes, including cell growth, tumor reversion, and induction of pluripotent stem cell. A recent study on the solution structure from fission yeast orthologue classifies TCTP under a family of small chaperone proteins. There is growing evidence in the literature that TCTP is a multifunctional protein and exerts its biological activity at the extracellular and intracellular levels. Although TCTP is not a tumor-specific protein, our research group, among several others, focused on the role(s) of TCTP in cancer progression. In this paper, we will summarize the current scientific knowledge of TCTP in different aspects, and the precise oncogenic mechanisms of TCTP will be discussed in detail. © Copyright 2012 Tim Hon Man Chan et al.
 
ISSN2090-2247
 
DOIhttp://dx.doi.org/10.1155/2012/369384
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorChan, THM
 
dc.contributor.authorChen, L
 
dc.contributor.authorGuan, XY
 
dc.date.accessioned2012-06-26T06:12:43Z
 
dc.date.available2012-06-26T06:12:43Z
 
dc.date.issued2012
 
dc.description.abstractTranslationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein in all eukaryoteshighlighting its important functions in the cell. Previous studies revealed that TCTP is implicated in many biological processes, including cell growth, tumor reversion, and induction of pluripotent stem cell. A recent study on the solution structure from fission yeast orthologue classifies TCTP under a family of small chaperone proteins. There is growing evidence in the literature that TCTP is a multifunctional protein and exerts its biological activity at the extracellular and intracellular levels. Although TCTP is not a tumor-specific protein, our research group, among several others, focused on the role(s) of TCTP in cancer progression. In this paper, we will summarize the current scientific knowledge of TCTP in different aspects, and the precise oncogenic mechanisms of TCTP will be discussed in detail. © Copyright 2012 Tim Hon Man Chan et al.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationBiochemistry Research International, 2012 [How to Cite?]
DOI: http://dx.doi.org/10.1155/2012/369384
 
dc.identifier.doihttp://dx.doi.org/10.1155/2012/369384
 
dc.identifier.issn2090-2247
 
dc.identifier.scopuseid_2-s2.0-84861040355
 
dc.identifier.urihttp://hdl.handle.net/10722/150857
 
dc.languageeng
 
dc.relation.ispartofBiochemistry Research International
 
dc.relation.referencesReferences in Scopus
 
dc.titleRole of translationally controlled tumor protein in cancer progression
 
dc.typeArticle
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Chan, THM</contributor.author>
<contributor.author>Chen, L</contributor.author>
<contributor.author>Guan, XY</contributor.author>
<date.accessioned>2012-06-26T06:12:43Z</date.accessioned>
<date.available>2012-06-26T06:12:43Z</date.available>
<date.issued>2012</date.issued>
<identifier.citation>Biochemistry Research International, 2012</identifier.citation>
<identifier.issn>2090-2247</identifier.issn>
<identifier.uri>http://hdl.handle.net/10722/150857</identifier.uri>
<description.abstract>Translationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein in all eukaryoteshighlighting its important functions in the cell. Previous studies revealed that TCTP is implicated in many biological processes, including cell growth, tumor reversion, and induction of pluripotent stem cell. A recent study on the solution structure from fission yeast orthologue classifies TCTP under a family of small chaperone proteins. There is growing evidence in the literature that TCTP is a multifunctional protein and exerts its biological activity at the extracellular and intracellular levels. Although TCTP is not a tumor-specific protein, our research group, among several others, focused on the role(s) of TCTP in cancer progression. In this paper, we will summarize the current scientific knowledge of TCTP in different aspects, and the precise oncogenic mechanisms of TCTP will be discussed in detail. &#169; Copyright 2012 Tim Hon Man Chan et al.</description.abstract>
<language>eng</language>
<relation.ispartof>Biochemistry Research International</relation.ispartof>
<title>Role of translationally controlled tumor protein in cancer progression</title>
<type>Article</type>
<description.nature>Link_to_subscribed_fulltext</description.nature>
<identifier.doi>10.1155/2012/369384</identifier.doi>
<identifier.scopus>eid_2-s2.0-84861040355</identifier.scopus>
<relation.references>http://www.scopus.com/mlt/select.url?eid=2-s2.0-84861040355&amp;selection=ref&amp;src=s&amp;origin=recordpage</relation.references>
</item>
Author Affiliations
  1. The University of Hong Kong Li Ka Shing Faculty of Medicine
  2. Sun Yat-Sen University Cancer Center
  3. The University of Hong Kong