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Article: Recurrent nasopharyngeal carcinoma: Surgical salvage vs. additional chemoradiation

TitleRecurrent nasopharyngeal carcinoma: Surgical salvage vs. additional chemoradiation
Authors
Keywordsradiation
recurrent nasopharyngeal carcinoma
salvage surgery
Issue Date2011
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-otolaryngology.com
Citation
Current Opinion In Otolaryngology And Head And Neck Surgery, 2011, v. 19 n. 2, p. 82-86 How to Cite?
AbstractPURPOSE OF REVIEW: The primary treatment modality of nasopharyngeal carcinoma (NPC) is radiation or chemoradiation. With the application of conformal radiation and appropriate chemotherapeutic agents, there was marked improvement in the outcome. Despite this, a small number of patients still develop residual or recurrent disease either in the neck or at the primary site. In recent years there are many developments in the disciplines of surgery, radiation and medical oncology which are applicable for the management of residual or recurrent NPC. It is timely to review the applicability and efficacy of the various therapeutic options. RECENT FINDINGS: The theme of the literature review included the management of these recurrent or residual diseases in the neck or nasopharynx with open or endoscopic or robot-assisted surgical approaches. The application of radiation techniques such as intensity modulated radiotherapy, stereotactic radiation and brachytherapy was also included. The use of chemotherapy and targeted agents is also reviewed. SUMMARY: In general, the size, extent and location of the residual or recurrent NPC together with the biological behaviour of the tumour determine the optimal therapy. The surgical and clinical oncological expertise applied optimally will give the best outcome. © 2011 Lippincott Williams & Wilkins, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/150835
ISSN
2015 Impact Factor: 1.586
2015 SCImago Journal Rankings: 0.885
ISI Accession Number ID
Funding AgencyGrant Number
Center for Nasopharyngeal Cancer Reseach, Hong KongAoE/M-06/08
Funding Information:

The authors wish to thank the Center for Nasopharyngeal Cancer Reseach, Hong Kong (grant number AoE/M-06/08) for their support.

References
Grants

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_HK
dc.contributor.authorKwong, DLWen_HK
dc.date.accessioned2012-06-26T06:11:44Z-
dc.date.available2012-06-26T06:11:44Z-
dc.date.issued2011en_HK
dc.identifier.citationCurrent Opinion In Otolaryngology And Head And Neck Surgery, 2011, v. 19 n. 2, p. 82-86en_HK
dc.identifier.issn1068-9508en_HK
dc.identifier.urihttp://hdl.handle.net/10722/150835-
dc.description.abstractPURPOSE OF REVIEW: The primary treatment modality of nasopharyngeal carcinoma (NPC) is radiation or chemoradiation. With the application of conformal radiation and appropriate chemotherapeutic agents, there was marked improvement in the outcome. Despite this, a small number of patients still develop residual or recurrent disease either in the neck or at the primary site. In recent years there are many developments in the disciplines of surgery, radiation and medical oncology which are applicable for the management of residual or recurrent NPC. It is timely to review the applicability and efficacy of the various therapeutic options. RECENT FINDINGS: The theme of the literature review included the management of these recurrent or residual diseases in the neck or nasopharynx with open or endoscopic or robot-assisted surgical approaches. The application of radiation techniques such as intensity modulated radiotherapy, stereotactic radiation and brachytherapy was also included. The use of chemotherapy and targeted agents is also reviewed. SUMMARY: In general, the size, extent and location of the residual or recurrent NPC together with the biological behaviour of the tumour determine the optimal therapy. The surgical and clinical oncological expertise applied optimally will give the best outcome. © 2011 Lippincott Williams & Wilkins, Inc.en_HK
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.co-otolaryngology.comen_HK
dc.relation.ispartofCurrent Opinion in Otolaryngology and Head and Neck Surgeryen_HK
dc.subjectradiationen_HK
dc.subjectrecurrent nasopharyngeal carcinomaen_HK
dc.subjectsalvage surgeryen_HK
dc.titleRecurrent nasopharyngeal carcinoma: Surgical salvage vs. additional chemoradiationen_HK
dc.typeArticleen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailKwong, DLW: dlwkwong@hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityKwong, DLW=rp00414en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1097/MOO.0b013e328344a599en_HK
dc.identifier.pmid21412154-
dc.identifier.scopuseid_2-s2.0-79953840298en_HK
dc.identifier.hkuros192372-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-79953840298&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume19en_HK
dc.identifier.issue2en_HK
dc.identifier.spage82en_HK
dc.identifier.epage86en_HK
dc.identifier.isiWOS:000288495300003-
dc.publisher.placeUnited Statesen_HK
dc.relation.projectCentre for Nasopharyngeal Carcinoma Research-
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridKwong, DLW=15744231600en_HK

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