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Article: Inverse planning in three-dimensional conformal and intensity-modulated radiotherapy of mid-thoracic oesophageal cancer

TitleInverse planning in three-dimensional conformal and intensity-modulated radiotherapy of mid-thoracic oesophageal cancer
Authors
Issue Date2004
PublisherBritish Institute of Radiology - BJR. The Journal's web site is located at http://bjr.birjournals.org
Citation
British Journal Of Radiology, 2004, v. 77 n. 919, p. 568-572 How to Cite?
AbstractThe aim of this study is to demonstrate the use of inverse planning in three-dimensional conformal radiation therapy (3DCRT) of oesophageal cancer patients and to evaluate its dosimetric results by comparing them with forward planning of 3DCRT and inverse planning of intensity-modulated radiotherapy (IMRT). For each of the 15 oesophageal cancer patients in this study, the forward 3DCRT, inverse 3DCRT and inverse IMRT plans were produced using the FOCUS treatment planning system. The dosimetric results and the planner's time associated with each of the treatment plans were recorded for comparison. The inverse 3DCRT plans showed similar dosimetric results to the forward plans in the planning target volume (PTV) and organs at risk (OARs). However, they were inferior to that of the IMRT plans in terms of tumour control probability and target dose conformity. Furthermore, the inverse 3DCRT plans were less effective in reducing the percentage lung volume receiving a dose below 25 Gy when compared with the IMRT plans. The inverse 3DCRT plans delivered a similar heart dose as in the forward plans, but higher dose than the IMRT plans. The inverse 3DCRT plans significantly reduced the operator's time by 2.5 fold relative to the forward plans. In conclusion, inverse planning for 3DCRT is a reasonable alternative to the forward planning for oesophageal cancer patients with reduction of the operator's time. However, IMRT has the better potential to allow further dose escalation and improvement of tumour control. © 2004 The British Institute of Radiology.
Persistent Identifierhttp://hdl.handle.net/10722/150819
ISSN
2015 Impact Factor: 1.84
2015 SCImago Journal Rankings: 0.834
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWu, VWCen_US
dc.contributor.authorSham, JSTen_US
dc.contributor.authorKwong, DLWen_US
dc.date.accessioned2012-06-26T06:11:15Z-
dc.date.available2012-06-26T06:11:15Z-
dc.date.issued2004en_US
dc.identifier.citationBritish Journal Of Radiology, 2004, v. 77 n. 919, p. 568-572en_US
dc.identifier.issn0007-1285en_US
dc.identifier.urihttp://hdl.handle.net/10722/150819-
dc.description.abstractThe aim of this study is to demonstrate the use of inverse planning in three-dimensional conformal radiation therapy (3DCRT) of oesophageal cancer patients and to evaluate its dosimetric results by comparing them with forward planning of 3DCRT and inverse planning of intensity-modulated radiotherapy (IMRT). For each of the 15 oesophageal cancer patients in this study, the forward 3DCRT, inverse 3DCRT and inverse IMRT plans were produced using the FOCUS treatment planning system. The dosimetric results and the planner's time associated with each of the treatment plans were recorded for comparison. The inverse 3DCRT plans showed similar dosimetric results to the forward plans in the planning target volume (PTV) and organs at risk (OARs). However, they were inferior to that of the IMRT plans in terms of tumour control probability and target dose conformity. Furthermore, the inverse 3DCRT plans were less effective in reducing the percentage lung volume receiving a dose below 25 Gy when compared with the IMRT plans. The inverse 3DCRT plans delivered a similar heart dose as in the forward plans, but higher dose than the IMRT plans. The inverse 3DCRT plans significantly reduced the operator's time by 2.5 fold relative to the forward plans. In conclusion, inverse planning for 3DCRT is a reasonable alternative to the forward planning for oesophageal cancer patients with reduction of the operator's time. However, IMRT has the better potential to allow further dose escalation and improvement of tumour control. © 2004 The British Institute of Radiology.en_US
dc.languageengen_US
dc.publisherBritish Institute of Radiology - BJR. The Journal's web site is located at http://bjr.birjournals.orgen_US
dc.relation.ispartofBritish Journal of Radiologyen_US
dc.subject.meshEsophageal Neoplasms - Pathology - Radiotherapyen_US
dc.subject.meshHeart - Radiation Effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshLung - Radiation Effectsen_US
dc.subject.meshRadiation Dosageen_US
dc.subject.meshRadiometry - Methodsen_US
dc.subject.meshRadiotherapy Dosageen_US
dc.subject.meshRadiotherapy Planning, Computer-Assisted - Methodsen_US
dc.subject.meshRadiotherapy, Conformal - Methodsen_US
dc.subject.meshSpinal Cord - Radiation Effectsen_US
dc.subject.meshTime Factorsen_US
dc.titleInverse planning in three-dimensional conformal and intensity-modulated radiotherapy of mid-thoracic oesophageal canceren_US
dc.typeArticleen_US
dc.identifier.emailKwong, DLW:dlwkwong@hku.hken_US
dc.identifier.authorityKwong, DLW=rp00414en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1259/bjr/19972578en_US
dc.identifier.pmid15238403-
dc.identifier.scopuseid_2-s2.0-4344608985en_US
dc.identifier.hkuros90190-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-4344608985&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume77en_US
dc.identifier.issue919en_US
dc.identifier.spage568en_US
dc.identifier.epage572en_US
dc.identifier.isiWOS:000222993100006-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridWu, VWC=7006045803en_US
dc.identifier.scopusauthoridSham, JST=24472255400en_US
dc.identifier.scopusauthoridKwong, DLW=15744231600en_US

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