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Article: Salivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma.

TitleSalivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma.
Authors
Issue Date2003
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00784/index.htm
Citation
Clinical Oral Investigations, 2003, v. 7 n. 4, p. 230-234 How to Cite?
AbstractNasopharyngeal carcinoma (NPC) is rare among Caucasians but very common among southern Chinese. No information is presently available on the relationship between salivary gland function and xerostomia in irradiated southern Chinese. Salivary gland function and xerostomia were measured in irradiated NPC patients, recently diagnosed NPC patients, and a matched control group. Stimulated whole saliva was collected from each participant and flow rate, pH and buffer capacity measured. All participants completed a multi-item dry mouth questionnaire. Comparisons were made using Chi-square and Mann-Whitney tests and correlations assessed using Spearman's rank correlation coefficients. The mean saliva flow rate and pH were significantly lower and the buffer capacity impaired in irradiated NPC patients compared with the other groups ( P<0.01). Significantly more irradiated NPC patients had negative impacts associated with dry mouth generally, sticky saliva, and hoarse voice ( P<0.01). Subjective dry mouth symptoms and associated reduced saliva flow were also relatively common in non-irradiated participants. Salivary gland hypofunction and xerostomia were major complications in irradiated NPC patients. In irradiated and non-irradiated southern Chinese, subjective dry mouth symptoms appeared to be correlated with actual salivary gland function.
Persistent Identifierhttp://hdl.handle.net/10722/150784
ISSN
2015 Impact Factor: 2.207
2015 SCImago Journal Rankings: 0.752
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPow, EHen_US
dc.contributor.authorMcmillan, ASen_US
dc.contributor.authorLeung, WKen_US
dc.contributor.authorWong, MCen_US
dc.contributor.authorKwong, DLen_US
dc.date.accessioned2012-06-26T06:10:28Z-
dc.date.available2012-06-26T06:10:28Z-
dc.date.issued2003en_US
dc.identifier.citationClinical Oral Investigations, 2003, v. 7 n. 4, p. 230-234en_US
dc.identifier.issn1432-6981en_US
dc.identifier.urihttp://hdl.handle.net/10722/150784-
dc.description.abstractNasopharyngeal carcinoma (NPC) is rare among Caucasians but very common among southern Chinese. No information is presently available on the relationship between salivary gland function and xerostomia in irradiated southern Chinese. Salivary gland function and xerostomia were measured in irradiated NPC patients, recently diagnosed NPC patients, and a matched control group. Stimulated whole saliva was collected from each participant and flow rate, pH and buffer capacity measured. All participants completed a multi-item dry mouth questionnaire. Comparisons were made using Chi-square and Mann-Whitney tests and correlations assessed using Spearman's rank correlation coefficients. The mean saliva flow rate and pH were significantly lower and the buffer capacity impaired in irradiated NPC patients compared with the other groups ( P<0.01). Significantly more irradiated NPC patients had negative impacts associated with dry mouth generally, sticky saliva, and hoarse voice ( P<0.01). Subjective dry mouth symptoms and associated reduced saliva flow were also relatively common in non-irradiated participants. Salivary gland hypofunction and xerostomia were major complications in irradiated NPC patients. In irradiated and non-irradiated southern Chinese, subjective dry mouth symptoms appeared to be correlated with actual salivary gland function.en_US
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00784/index.htmen_US
dc.relation.ispartofClinical oral investigationsen_US
dc.subject.meshAnalysis Of Varianceen_US
dc.subject.meshCase-Control Studiesen_US
dc.subject.meshChi-Square Distributionen_US
dc.subject.meshChinaen_US
dc.subject.meshCranial Irradiation - Adverse Effectsen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNasopharyngeal Neoplasms - Radiotherapyen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshRadiation Injuries - Complicationsen_US
dc.subject.meshSaliva - Secretionen_US
dc.subject.meshSalivary Glands - Physiopathology - Radiation Effectsen_US
dc.subject.meshSalivation - Radiation Effectsen_US
dc.subject.meshStatistics, Nonparametricen_US
dc.subject.meshXerostomia - Etiologyen_US
dc.titleSalivary gland function and xerostomia in southern Chinese following radiotherapy for nasopharyngeal carcinoma.en_US
dc.typeArticleen_US
dc.identifier.emailPow, EH:ehnpow@hku.hken_US
dc.identifier.emailMcMillan, AS:annemcmillan@hku.hken_US
dc.identifier.emailLeung, WK:ewkleung@hkucc.hku.hken_US
dc.identifier.emailWong, MC:mcmwong@hkucc.hku.hken_US
dc.identifier.emailKwong, DL:dlwkwong@hku.hken_US
dc.identifier.authorityPow, EH=rp00030en_US
dc.identifier.authorityMcMillan, AS=rp00014en_US
dc.identifier.authorityLeung, WK=rp00019en_US
dc.identifier.authorityWong, MC=rp00024en_US
dc.identifier.authorityKwong, DL=rp00414en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid12955605-
dc.identifier.scopuseid_2-s2.0-0348019131en_US
dc.identifier.hkuros85589-
dc.identifier.volume7en_US
dc.identifier.issue4en_US
dc.identifier.spage230en_US
dc.identifier.epage234en_US
dc.identifier.isiWOS:000208381200009-
dc.publisher.placeGermanyen_US
dc.identifier.scopusauthoridPow, EH=6603825799en_US
dc.identifier.scopusauthoridMcMillan, AS=7102843317en_US
dc.identifier.scopusauthoridLeung, WK=25224691800en_US
dc.identifier.scopusauthoridWong, MC=26029250900en_US
dc.identifier.scopusauthoridKwong, DL=15744231600en_US

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