File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1053/ajot.2002.123436
- Scopus: eid_2-s2.0-0036303542
- PMID: 12105785
- WOS: WOS:000176673200004
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Change in olfaction after radiotherapy for nasopharyngeal cancer - A prospective study
Title | Change in olfaction after radiotherapy for nasopharyngeal cancer - A prospective study |
---|---|
Authors | |
Issue Date | 2002 |
Publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/amjoto |
Citation | American Journal Of Otolaryngology - Head And Neck Medicine And Surgery, 2002, v. 23 n. 4, p. 209-214 How to Cite? |
Abstract | Purpose: To evaluate the changes in olfactory function in patients with nasopharyngeal carcinoma who have received radiation to the head and neck. Materials and Methods: Olfactory function of consecutive patients with nasopharyngeal carcinoma was assessed prospectively before irradiation and serially up to 1 year after radiotherapy by the Sniffin' Sticks (Erlangen, Germany) olfactory function test and by a patient symptom visual analogue scale. Results: Fifty-eight patients were recruited before radiotherapy was commenced. Three patients could not give a reliable response to the Sniffin' Sticks test even in this first assessment, and 7 patients did not return for evaluation after irradiation. Forty-eight patients were available for follow-up assessment. Mean olfactory threshold scores by the Sniffin' Sticks test were found to deteriorate significantly at 12 months when compared with the scores before irradiation (8.3 at 12 months vs 11.5 before irradiation; P = .001). Scores for olfactory discrimination and for identification did not exhibit any significant changes when assessed at 12 months (P gt; .05 for both). Subjective patient assessment of olfactory function with the visual analogue scale at 12 months did not demonstrate any significant differences when compared with patients' assessment before irradiation (P = .90). An increase in discharge was the only nasal symptom that demonstrated a significant change at 12 months when compared with the assessment before irradiation (P lt; 001). Conclusions: Deterioration in olfactory threshold scores was found at 12 months after irradiation and was not noticed by the patients. Copyright 2002, Elsevier Science (USA). All rights reserved. |
Persistent Identifier | http://hdl.handle.net/10722/150764 |
ISSN | 2023 Impact Factor: 1.8 2023 SCImago Journal Rankings: 0.648 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ho, WK | en_US |
dc.contributor.author | Kwong, DLW | en_US |
dc.contributor.author | Wei, WI | en_US |
dc.contributor.author | Sham, JST | en_US |
dc.date.accessioned | 2012-06-26T06:10:02Z | - |
dc.date.available | 2012-06-26T06:10:02Z | - |
dc.date.issued | 2002 | en_US |
dc.identifier.citation | American Journal Of Otolaryngology - Head And Neck Medicine And Surgery, 2002, v. 23 n. 4, p. 209-214 | en_US |
dc.identifier.issn | 0196-0709 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/150764 | - |
dc.description.abstract | Purpose: To evaluate the changes in olfactory function in patients with nasopharyngeal carcinoma who have received radiation to the head and neck. Materials and Methods: Olfactory function of consecutive patients with nasopharyngeal carcinoma was assessed prospectively before irradiation and serially up to 1 year after radiotherapy by the Sniffin' Sticks (Erlangen, Germany) olfactory function test and by a patient symptom visual analogue scale. Results: Fifty-eight patients were recruited before radiotherapy was commenced. Three patients could not give a reliable response to the Sniffin' Sticks test even in this first assessment, and 7 patients did not return for evaluation after irradiation. Forty-eight patients were available for follow-up assessment. Mean olfactory threshold scores by the Sniffin' Sticks test were found to deteriorate significantly at 12 months when compared with the scores before irradiation (8.3 at 12 months vs 11.5 before irradiation; P = .001). Scores for olfactory discrimination and for identification did not exhibit any significant changes when assessed at 12 months (P gt; .05 for both). Subjective patient assessment of olfactory function with the visual analogue scale at 12 months did not demonstrate any significant differences when compared with patients' assessment before irradiation (P = .90). An increase in discharge was the only nasal symptom that demonstrated a significant change at 12 months when compared with the assessment before irradiation (P lt; 001). Conclusions: Deterioration in olfactory threshold scores was found at 12 months after irradiation and was not noticed by the patients. Copyright 2002, Elsevier Science (USA). All rights reserved. | en_US |
dc.language | eng | en_US |
dc.publisher | WB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/amjoto | en_US |
dc.relation.ispartof | American Journal of Otolaryngology - Head and Neck Medicine and Surgery | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Follow-Up Studies | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Nasopharyngeal Neoplasms - Physiopathology - Radiotherapy | en_US |
dc.subject.mesh | Prospective Studies | en_US |
dc.subject.mesh | Self-Assessment | en_US |
dc.subject.mesh | Smell - Physiology | en_US |
dc.title | Change in olfaction after radiotherapy for nasopharyngeal cancer - A prospective study | en_US |
dc.type | Article | en_US |
dc.identifier.email | Kwong, DLW:dlwkwong@hku.hk | en_US |
dc.identifier.email | Wei, WI:hrmswwi@hku.hk | en_US |
dc.identifier.authority | Kwong, DLW=rp00414 | en_US |
dc.identifier.authority | Wei, WI=rp00323 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1053/ajot.2002.123436 | en_US |
dc.identifier.pmid | 12105785 | - |
dc.identifier.scopus | eid_2-s2.0-0036303542 | en_US |
dc.identifier.hkuros | 70220 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0036303542&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 23 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.spage | 209 | en_US |
dc.identifier.epage | 214 | en_US |
dc.identifier.isi | WOS:000176673200004 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Ho, WK=7402968844 | en_US |
dc.identifier.scopusauthorid | Kwong, DLW=15744231600 | en_US |
dc.identifier.scopusauthorid | Wei, WI=7403321552 | en_US |
dc.identifier.scopusauthorid | Sham, JST=24472255400 | en_US |
dc.identifier.issnl | 0196-0709 | - |