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Article: Identification of a ring chromosome in a myxoid malignant fibrous histiocytoma with chromosome microdissection and fluorescence in situ hybridization

TitleIdentification of a ring chromosome in a myxoid malignant fibrous histiocytoma with chromosome microdissection and fluorescence in situ hybridization
Authors
Issue Date1999
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 1999, v. 109 n. 1, p. 81-85 How to Cite?
AbstractWe investigated the origin of a ring chromosome in a myxoid malignant fibrous histiocytoma (MFH) by microdissection and fluorescence in situ hybridization (FISH) analyses. Cytogenetically, only two ring chromosomes were observed; the smaller ring was seen more frequently. The latter was microdissected, and the material used for FISH. Hybridization of the microdissected labeled DNA to normal metaphase cells revealed that the signal localized only to 20q. Three signals were seen in the tumor cells using either the microdissected 20q probe or chromosome 20 centromeric probe, indicating the involvement of both the long arm and the centromere in the ring chromosome. The short arm of chromosome 20 did not appear to be involved in the formation of the ring chromosome.
Persistent Identifierhttp://hdl.handle.net/10722/150747
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMeloniEhrig, AMen_US
dc.contributor.authorChen, Zen_US
dc.contributor.authorGuan, XYen_US
dc.contributor.authorNotohamiprodjo, Men_US
dc.contributor.authorShepard, RRen_US
dc.contributor.authorSpanier, SSen_US
dc.contributor.authorTrent, JMen_US
dc.contributor.authorSandberg, AAen_US
dc.date.accessioned2012-06-26T06:09:45Z-
dc.date.available2012-06-26T06:09:45Z-
dc.date.issued1999en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 1999, v. 109 n. 1, p. 81-85en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/150747-
dc.description.abstractWe investigated the origin of a ring chromosome in a myxoid malignant fibrous histiocytoma (MFH) by microdissection and fluorescence in situ hybridization (FISH) analyses. Cytogenetically, only two ring chromosomes were observed; the smaller ring was seen more frequently. The latter was microdissected, and the material used for FISH. Hybridization of the microdissected labeled DNA to normal metaphase cells revealed that the signal localized only to 20q. Three signals were seen in the tumor cells using either the microdissected 20q probe or chromosome 20 centromeric probe, indicating the involvement of both the long arm and the centromere in the ring chromosome. The short arm of chromosome 20 did not appear to be involved in the formation of the ring chromosome.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.subject.meshAdulten_US
dc.subject.meshBiopsyen_US
dc.subject.meshCentromere - Geneticsen_US
dc.subject.meshChromosome Mappingen_US
dc.subject.meshChromosomes, Human, Pair 20en_US
dc.subject.meshFemaleen_US
dc.subject.meshHistiocytoma, Benign Fibrous - Genetics - Pathology - Surgeryen_US
dc.subject.meshHumansen_US
dc.subject.meshIn Situ Hybridization, Fluorescenceen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshRing Chromosomesen_US
dc.titleIdentification of a ring chromosome in a myxoid malignant fibrous histiocytoma with chromosome microdissection and fluorescence in situ hybridizationen_US
dc.typeArticleen_US
dc.identifier.emailGuan, XY:xyguan@hkucc.hku.hken_US
dc.identifier.authorityGuan, XY=rp00454en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(98)00151-4en_US
dc.identifier.pmid9973967-
dc.identifier.scopuseid_2-s2.0-0033081735en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033081735&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume109en_US
dc.identifier.issue1en_US
dc.identifier.spage81en_US
dc.identifier.epage85en_US
dc.identifier.isiWOS:000078251300015-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridMeloniEhrig, AM=6603143970en_US
dc.identifier.scopusauthoridChen, Z=7409491627en_US
dc.identifier.scopusauthoridGuan, XY=7201463221en_US
dc.identifier.scopusauthoridNotohamiprodjo, M=6508174023en_US
dc.identifier.scopusauthoridShepard, RR=7102027295en_US
dc.identifier.scopusauthoridSpanier, SS=7005293167en_US
dc.identifier.scopusauthoridTrent, JM=7201692482en_US
dc.identifier.scopusauthoridSandberg, AA=7202853810en_US

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