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Article: Detection of chromosome 12q amplification in sarcomas by chromosome microdissection and interphase FISH

TitleDetection of chromosome 12q amplification in sarcomas by chromosome microdissection and interphase FISH
Authors
Mitchell, DSGuan, XYMeltzer, PS
KeywordsChromosome 12Q Amplification
Chromosome Microdissection
Interphase Fsh
Sarcomas
Issue Date1994
PublisherSpandidos Publications. The Journal's web site is located at http://www.spandidos-publications.com/ijo/
Citation
International Journal Of Oncology, 1994, v. 5 n. 4, p. 787-792 How to Cite?
AbstractWe describe the microdissection of a homogeneously staining region (hsr) in the neuroblastoma cell line NGP-127 which contains the SAS gene. Fluorescence in situ hybridization (FISH) of this probe to NGP-127 cells confirms its derivation from the hsr while FISH: to normal chromosomes establishes that the hsr is composed of sequences from two segments of chromosome 12q. The hsr microdissection probe yields fluorescent signals which are sufficiently intense to readily identify amplification of homologous sequences in interphase nuclei.
Persistent Identifierhttp://hdl.handle.net/10722/150706
ISSN
1019-6439
2023 Impact Factor: 4.5
2023 SCImago Journal Rankings: 1.099

 

DC FieldValueLanguage
dc.contributor.authorMitchell, DSen_US
dc.contributor.authorGuan, XYen_US
dc.contributor.authorMeltzer, PSen_US
dc.date.accessioned2012-06-26T06:09:02Z-
dc.date.available2012-06-26T06:09:02Z-
dc.date.issued1994en_US
dc.identifier.citationInternational Journal Of Oncology, 1994, v. 5 n. 4, p. 787-792en_US
dc.identifier.issn1019-6439en_US
dc.identifier.urihttp://hdl.handle.net/10722/150706-
dc.description.abstractWe describe the microdissection of a homogeneously staining region (hsr) in the neuroblastoma cell line NGP-127 which contains the SAS gene. Fluorescence in situ hybridization (FISH) of this probe to NGP-127 cells confirms its derivation from the hsr while FISH: to normal chromosomes establishes that the hsr is composed of sequences from two segments of chromosome 12q. The hsr microdissection probe yields fluorescent signals which are sufficiently intense to readily identify amplification of homologous sequences in interphase nuclei.en_US
dc.languageengen_US
dc.publisherSpandidos Publications. The Journal's web site is located at http://www.spandidos-publications.com/ijo/en_US
dc.relation.ispartofInternational Journal of Oncologyen_US
dc.subjectChromosome 12Q Amplificationen_US
dc.subjectChromosome Microdissectionen_US
dc.subjectInterphase Fshen_US
dc.subjectSarcomasen_US
dc.titleDetection of chromosome 12q amplification in sarcomas by chromosome microdissection and interphase FISHen_US
dc.typeArticleen_US
dc.identifier.emailGuan, XY:xyguan@hkucc.hku.hken_US
dc.identifier.authorityGuan, XY=rp00454en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-0028016098en_US
dc.identifier.volume5en_US
dc.identifier.issue4en_US
dc.identifier.spage787en_US
dc.identifier.epage792en_US
dc.publisher.placeGreeceen_US
dc.identifier.scopusauthoridMitchell, DS=7403870847en_US
dc.identifier.scopusauthoridGuan, XY=7201463221en_US
dc.identifier.scopusauthoridMeltzer, PS=7102464641en_US
dc.identifier.issnl1019-6439-

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