File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Epstein-Barr virus genotypes associated with nasopharyngeal carcinoma in Southern China

TitleEpstein-Barr virus genotypes associated with nasopharyngeal carcinoma in Southern China
Authors
Issue Date1990
PublisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/yviro
Citation
Virology, 1990, v. 177 n. 1, p. 44-53 How to Cite?
AbstractWe have used probes presenting approximately two-thirds of the Epstein-Barr virus (EBV) genome to examine genetic polymorphism of wild-type EBV directly detected in 28 nasopharyngeal carcinoma (NPC) tissues from Southern China. In the hypervariable regions containing reiterated sequences, this analysis showed that while naturally occurring viruses are genetically diverse, only one genotype was detectable in each tumor specimen. Unique variants in NPC were detected in four regions of the EBV genome. Two of these appeared significant in their distribution. The type C variant resulting from loss of a BamHI site between the BamHI W1* and l1* regions was prevalent among isolates from Southern China, but not so common in the United States. An 'f' variant having an extra BamHI site in the BamHI F region was almost exclusively detected in only Asian NPC biopsies.
Persistent Identifierhttp://hdl.handle.net/10722/150691
ISSN
2015 Impact Factor: 3.2
2015 SCImago Journal Rankings: 1.805
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLung, MLen_US
dc.contributor.authorChang, RSen_US
dc.contributor.authorHuang, MLen_US
dc.contributor.authorGuo, HYen_US
dc.contributor.authorChoy, Den_US
dc.contributor.authorSham, Jen_US
dc.contributor.authorTsao, SYen_US
dc.contributor.authorCheng, Pen_US
dc.contributor.authorNg, MHen_US
dc.date.accessioned2012-06-26T06:08:51Z-
dc.date.available2012-06-26T06:08:51Z-
dc.date.issued1990en_US
dc.identifier.citationVirology, 1990, v. 177 n. 1, p. 44-53en_US
dc.identifier.issn0042-6822en_US
dc.identifier.urihttp://hdl.handle.net/10722/150691-
dc.description.abstractWe have used probes presenting approximately two-thirds of the Epstein-Barr virus (EBV) genome to examine genetic polymorphism of wild-type EBV directly detected in 28 nasopharyngeal carcinoma (NPC) tissues from Southern China. In the hypervariable regions containing reiterated sequences, this analysis showed that while naturally occurring viruses are genetically diverse, only one genotype was detectable in each tumor specimen. Unique variants in NPC were detected in four regions of the EBV genome. Two of these appeared significant in their distribution. The type C variant resulting from loss of a BamHI site between the BamHI W1* and l1* regions was prevalent among isolates from Southern China, but not so common in the United States. An 'f' variant having an extra BamHI site in the BamHI F region was almost exclusively detected in only Asian NPC biopsies.en_US
dc.languageengen_US
dc.publisherAcademic Press. The Journal's web site is located at http://www.elsevier.com/locate/yviroen_US
dc.relation.ispartofVirologyen_US
dc.subject.meshBiopsyen_US
dc.subject.meshBlotting, Southernen_US
dc.subject.meshCell Lineen_US
dc.subject.meshChinaen_US
dc.subject.meshDna, Viral - Genetics - Isolation & Purificationen_US
dc.subject.meshDeoxyribonuclease Bamhien_US
dc.subject.meshGenetic Variationen_US
dc.subject.meshGenotypeen_US
dc.subject.meshHerpesvirus 4, Human - Genetics - Isolation & Purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshNasopharyngeal Neoplasms - Microbiology - Pathologyen_US
dc.subject.meshRestriction Mappingen_US
dc.titleEpstein-Barr virus genotypes associated with nasopharyngeal carcinoma in Southern Chinaen_US
dc.typeArticleen_US
dc.identifier.emailLung, ML:mlilung@hku.hken_US
dc.identifier.authorityLung, ML=rp00300en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0042-6822(90)90458-4en_US
dc.identifier.pmid2162115-
dc.identifier.scopuseid_2-s2.0-0025345671en_US
dc.identifier.volume177en_US
dc.identifier.issue1en_US
dc.identifier.spage44en_US
dc.identifier.epage53en_US
dc.identifier.isiWOS:A1990DK26100005-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridLung, ML=7006411788en_US
dc.identifier.scopusauthoridChang, RS=7403713102en_US
dc.identifier.scopusauthoridHuang, ML=11540633300en_US
dc.identifier.scopusauthoridGuo, HY=34769789200en_US
dc.identifier.scopusauthoridChoy, D=8663654500en_US
dc.identifier.scopusauthoridSham, J=24472255400en_US
dc.identifier.scopusauthoridTsao, SY=7102813104en_US
dc.identifier.scopusauthoridCheng, P=7401618786en_US
dc.identifier.scopusauthoridNg, MH=7202076421en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats