File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1007/s10571-007-9181-x
- Scopus: eid_2-s2.0-46149090121
- PMID: 17710531
- WOS: WOS:000257223300002
- Find via
Supplementary
- Citations:
- Appears in Collections:
Article: Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far?
Title | Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? |
---|---|
Authors | |
Keywords | Anti-aging Herbal medicine Lycium barbsarum Neuroprotection Polysaccharides |
Issue Date | 2008 |
Publisher | Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0272-4340 |
Citation | Cellular And Molecular Neurobiology, 2008, v. 28 n. 5, p. 643-652 How to Cite? |
Abstract | Lycium barbarum (Gouqizi, Fructus Lycii, Wolfberry) is well known for nourishing the liver, and in turn, improving the eyesight. However, many people have forgotten its anti-aging properties. Valuable components of L. barbarum are not limited to its colored components containing zeaxanthin and carotene, but include the polysaccharides and small molecules such as betaine, cerebroside, β-sitosterol, p-coumaric, and various vitamins. Despite the fact that L. barbarum has been used for centuries, its beneficial effects to our bodies have not been comprehensively studied with modern technology to unravel its therapeutic effects at the biochemical level. Recently, our laboratory has demonstrated its neuroprotective effects to counter neuronal loss in neurodegenerative diseases. Polysaccharides extracted from L. barbarum can protect neurons against β-amyloid peptide toxicity in neuronal cell cultures, and retinal ganglion cells in an experimental model of glaucoma. We have even isolated the active component of polysaccharide which can attenuate stress kinases and pro-apoptotic signaling pathways. We have accumulated scientific evidence for its anti-aging effects that should be highlighted for modern preventive medicine. This review is to provide background information and a new direction of study for the anti-aging properties of L. barbarum. We hope that new findings for L. barbarum will pave a new avenue for the use of Chinese medicine in modern evidence-based medicine. © 2007 Springer Science+Business Media, LLC. |
Persistent Identifier | http://hdl.handle.net/10722/149696 |
ISSN | 2023 Impact Factor: 3.6 2023 SCImago Journal Rankings: 1.118 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chang, RCC | en_US |
dc.contributor.author | So, KF | en_US |
dc.date.accessioned | 2012-06-26T05:57:12Z | - |
dc.date.available | 2012-06-26T05:57:12Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.citation | Cellular And Molecular Neurobiology, 2008, v. 28 n. 5, p. 643-652 | en_US |
dc.identifier.issn | 0272-4340 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/149696 | - |
dc.description.abstract | Lycium barbarum (Gouqizi, Fructus Lycii, Wolfberry) is well known for nourishing the liver, and in turn, improving the eyesight. However, many people have forgotten its anti-aging properties. Valuable components of L. barbarum are not limited to its colored components containing zeaxanthin and carotene, but include the polysaccharides and small molecules such as betaine, cerebroside, β-sitosterol, p-coumaric, and various vitamins. Despite the fact that L. barbarum has been used for centuries, its beneficial effects to our bodies have not been comprehensively studied with modern technology to unravel its therapeutic effects at the biochemical level. Recently, our laboratory has demonstrated its neuroprotective effects to counter neuronal loss in neurodegenerative diseases. Polysaccharides extracted from L. barbarum can protect neurons against β-amyloid peptide toxicity in neuronal cell cultures, and retinal ganglion cells in an experimental model of glaucoma. We have even isolated the active component of polysaccharide which can attenuate stress kinases and pro-apoptotic signaling pathways. We have accumulated scientific evidence for its anti-aging effects that should be highlighted for modern preventive medicine. This review is to provide background information and a new direction of study for the anti-aging properties of L. barbarum. We hope that new findings for L. barbarum will pave a new avenue for the use of Chinese medicine in modern evidence-based medicine. © 2007 Springer Science+Business Media, LLC. | en_US |
dc.language | eng | en_US |
dc.publisher | Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0272-4340 | en_US |
dc.relation.ispartof | Cellular and Molecular Neurobiology | en_US |
dc.subject | Anti-aging | - |
dc.subject | Herbal medicine | - |
dc.subject | Lycium barbsarum | - |
dc.subject | Neuroprotection | - |
dc.subject | Polysaccharides | - |
dc.subject.mesh | Aging - Drug Effects - Metabolism | en_US |
dc.subject.mesh | Amyloid Beta-Peptides - Antagonists & Inhibitors - Toxicity | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Apoptosis - Drug Effects | en_US |
dc.subject.mesh | Brain - Drug Effects - Metabolism - Physiopathology | en_US |
dc.subject.mesh | Drugs, Chinese Herbal - Pharmacology - Therapeutic Use | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Neurodegenerative Diseases - Drug Therapy - Metabolism - Physiopathology | en_US |
dc.subject.mesh | Neurons - Drug Effects - Metabolism - Pathology | en_US |
dc.subject.mesh | Neuroprotective Agents - Pharmacology - Therapeutic Use | en_US |
dc.subject.mesh | Oxidative Stress - Drug Effects | en_US |
dc.title | Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chang, RCC:rccchang@hkucc.hku.hk | en_US |
dc.identifier.email | So, KF:hrmaskf@hkucc.hku.hk | en_US |
dc.identifier.authority | Chang, RCC=rp00470 | en_US |
dc.identifier.authority | So, KF=rp00329 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1007/s10571-007-9181-x | en_US |
dc.identifier.pmid | 17710531 | - |
dc.identifier.scopus | eid_2-s2.0-46149090121 | en_US |
dc.identifier.hkuros | 150973 | - |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-46149090121&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 28 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.spage | 643 | en_US |
dc.identifier.epage | 652 | en_US |
dc.identifier.isi | WOS:000257223300002 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Chang, RCC=7403713410 | en_US |
dc.identifier.scopusauthorid | So, KF=34668391300 | en_US |
dc.identifier.issnl | 0272-4340 | - |