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Article: Expression of Vascular Endothelial Growth Factor (VEGF) and its receptors in the golden hamster uterus during implantation

TitleExpression of Vascular Endothelial Growth Factor (VEGF) and its receptors in the golden hamster uterus during implantation
Authors
Issue Date1998
PublisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.fasebj.org/
Citation
Faseb Journal, 1998, v. 12 n. 5, p. A725 How to Cite?
AbstractExpression of VEGF and its receptors Flt-1 and Flk-1 during embryonic implantation (days 3-7) was studied in the uterus by immunohistochemistry. The lectin BS-1 (Bandeiraea simplicifolia) was used to label newly-formed endothelial cells. VEGF was expressed by all embryonic cells between days 4-7. VEGF and Flt-1 expression was observed in decidual cells on days 5-7. Flk-1 immunoreactivity was localized in newly-formed endothelial cells sprouting at the antimesometrial pole. BS-1 binding was found in decidual cells at the antimesometrial pole. Our data indicate that VEGF and its receptors may play a role in facilitating blood supply at the implantation site. The fact that VEGF is found in the embryo a day earlier suggests that the implanting conceptus may signal implantation by initiating angiogenic response in the endometrium.
Persistent Identifierhttp://hdl.handle.net/10722/149664
ISSN
2015 Impact Factor: 5.299
2015 SCImago Journal Rankings: 2.775

 

DC FieldValueLanguage
dc.contributor.authorJiang, HYen_US
dc.contributor.authorTang, PLen_US
dc.contributor.authorO, WSen_US
dc.contributor.authorYi, XJen_US
dc.contributor.authorChow, PHen_US
dc.date.accessioned2012-06-26T05:56:44Z-
dc.date.available2012-06-26T05:56:44Z-
dc.date.issued1998en_US
dc.identifier.citationFaseb Journal, 1998, v. 12 n. 5, p. A725en_US
dc.identifier.issn0892-6638en_US
dc.identifier.urihttp://hdl.handle.net/10722/149664-
dc.description.abstractExpression of VEGF and its receptors Flt-1 and Flk-1 during embryonic implantation (days 3-7) was studied in the uterus by immunohistochemistry. The lectin BS-1 (Bandeiraea simplicifolia) was used to label newly-formed endothelial cells. VEGF was expressed by all embryonic cells between days 4-7. VEGF and Flt-1 expression was observed in decidual cells on days 5-7. Flk-1 immunoreactivity was localized in newly-formed endothelial cells sprouting at the antimesometrial pole. BS-1 binding was found in decidual cells at the antimesometrial pole. Our data indicate that VEGF and its receptors may play a role in facilitating blood supply at the implantation site. The fact that VEGF is found in the embryo a day earlier suggests that the implanting conceptus may signal implantation by initiating angiogenic response in the endometrium.en_US
dc.languageengen_US
dc.publisherFederation of American Societies for Experimental Biology. The Journal's web site is located at http://www.fasebj.org/en_US
dc.relation.ispartofFASEB Journalen_US
dc.titleExpression of Vascular Endothelial Growth Factor (VEGF) and its receptors in the golden hamster uterus during implantationen_US
dc.typeArticleen_US
dc.identifier.emailO, WS:owaisum@hkucc.hku.hken_US
dc.identifier.authorityO, WS=rp00315en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33749230865en_US
dc.identifier.volume12en_US
dc.identifier.issue5en_US
dc.identifier.spageA725en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridJiang, HY=34769714800en_US
dc.identifier.scopusauthoridTang, PL=7202102495en_US
dc.identifier.scopusauthoridO, WS=6701729369en_US
dc.identifier.scopusauthoridYi, XJ=7202268837en_US
dc.identifier.scopusauthoridChow, PH=7202656919en_US

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