File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Quantitative Analysis of Brain Edema Resolution into the Cerebral Ventricles and Subarachnoid Space

TitleQuantitative Analysis of Brain Edema Resolution into the Cerebral Ventricles and Subarachnoid Space
Authors
Issue Date1997
Citation
Acta Neurochirurgica, Supplement, 1997, v. 1997 n. 70, p. 288-290 How to Cite?
AbstractResolution of vasogenic brain edema was examined using a model of infusion of fluid into the brain of rabbits. For this purpose infusion of Texas Red-albumin (MW 67.000 D) and sodium fluorescein (MW 376 D) dissolved in artificial cerebrospinal fluid (mock CSF) was made into the white matter of the left frontal lobe of the brain. In order to quantify the portion of edema fluid which was cleared by the ventricular system, a ventriculo-cisternal perfusion was performed with mock CSF. A closed cranial window was implanted above the left parietal brain for superfusion of the cerebral cortex with mock CSF, in order to study resolution of the artificial edema fluid via the subarachnoid space. CSF-samples were collected in 30 minutes-intervals and analysed with a spectrophotometer. The clearance of edema fluid was examined under low (2-5 mmHg) and medium (9-12 mmHg) intracranial pressure (ICP). In the low-pressure group both edema fluid markers were found in the ventriculo-cisternal and subarachnoid perfusate at 60 min and 90 min, respectively, after start of infusion. In the group with moderately increased ICP the markers appeared at 90 min and 120 min, respectively. The amount of clearance of fluorescent dye via the subarachnoid space was the same in both groups and independent of the intracranial pressure.
Persistent Identifierhttp://hdl.handle.net/10722/149567
ISSN
2015 SCImago Journal Rankings: 0.379
References

 

DC FieldValueLanguage
dc.contributor.authorWrba, Een_US
dc.contributor.authorNehring, Ven_US
dc.contributor.authorChang, RCCen_US
dc.contributor.authorBaethmann, Aen_US
dc.contributor.authorReulen, HJen_US
dc.contributor.authorUhl, Een_US
dc.date.accessioned2012-06-26T05:55:22Z-
dc.date.available2012-06-26T05:55:22Z-
dc.date.issued1997en_US
dc.identifier.citationActa Neurochirurgica, Supplement, 1997, v. 1997 n. 70, p. 288-290en_US
dc.identifier.issn0065-1419en_US
dc.identifier.urihttp://hdl.handle.net/10722/149567-
dc.description.abstractResolution of vasogenic brain edema was examined using a model of infusion of fluid into the brain of rabbits. For this purpose infusion of Texas Red-albumin (MW 67.000 D) and sodium fluorescein (MW 376 D) dissolved in artificial cerebrospinal fluid (mock CSF) was made into the white matter of the left frontal lobe of the brain. In order to quantify the portion of edema fluid which was cleared by the ventricular system, a ventriculo-cisternal perfusion was performed with mock CSF. A closed cranial window was implanted above the left parietal brain for superfusion of the cerebral cortex with mock CSF, in order to study resolution of the artificial edema fluid via the subarachnoid space. CSF-samples were collected in 30 minutes-intervals and analysed with a spectrophotometer. The clearance of edema fluid was examined under low (2-5 mmHg) and medium (9-12 mmHg) intracranial pressure (ICP). In the low-pressure group both edema fluid markers were found in the ventriculo-cisternal and subarachnoid perfusate at 60 min and 90 min, respectively, after start of infusion. In the group with moderately increased ICP the markers appeared at 90 min and 120 min, respectively. The amount of clearance of fluorescent dye via the subarachnoid space was the same in both groups and independent of the intracranial pressure.en_US
dc.languageengen_US
dc.relation.ispartofActa Neurochirurgica, Supplementen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBrain Edema - Physiopathologyen_US
dc.subject.meshCerebral Ventricles - Physiopathologyen_US
dc.subject.meshCerebrospinal Fluid - Physiologyen_US
dc.subject.meshFluorescent Dyesen_US
dc.subject.meshMolecular Weighten_US
dc.subject.meshRabbitsen_US
dc.subject.meshSubarachnoid Space - Physiopathologyen_US
dc.titleQuantitative Analysis of Brain Edema Resolution into the Cerebral Ventricles and Subarachnoid Spaceen_US
dc.typeArticleen_US
dc.identifier.emailChang, RCC:rccchang@hkucc.hku.hken_US
dc.identifier.authorityChang, RCC=rp00470en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid9416349-
dc.identifier.scopuseid_2-s2.0-0031304457en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0031304457&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume1997en_US
dc.identifier.issue70en_US
dc.identifier.spage288en_US
dc.identifier.epage290en_US
dc.publisher.placeAustriaen_US
dc.identifier.scopusauthoridWrba, E=6507130530en_US
dc.identifier.scopusauthoridNehring, V=6602301916en_US
dc.identifier.scopusauthoridChang, RCC=7403713410en_US
dc.identifier.scopusauthoridBaethmann, A=7004994793en_US
dc.identifier.scopusauthoridReulen, HJ=7006146584en_US
dc.identifier.scopusauthoridUhl, E=7004972666en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats