File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Expression of c-jun and neuronal nitric oxide synthase in rat spinal motoneurons following axonal injury

TitleExpression of c-jun and neuronal nitric oxide synthase in rat spinal motoneurons following axonal injury
Authors
Issue Date1994
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neulet
Citation
Neuroscience Letters, 1994, v. 179 n. 1-2, p. 157-161 How to Cite?
AbstractExpression of neuronal NOS, c-jun and c-fos in spinal motoneurons following axonal damage were investigated in the present study. Although either distal spinal root axotomy or root avulsion induced expression of c-jun, expression of c-jun was predominantly found in distal root-axotomized motoneurons. In contrast, expression of NOS was exclusively observed in avulsed motoneurons. c-fos was not expressed in spinal motoneurons following either distal root axotomy or root avulsion. The different expression patterns of c-jun and NOS in the injured neurons suggest that these molecules may involve in different cellular processes and might play different roles in response to the injury. Since distal root axotomy did not cause motoneuron death and root avulsion did, expression of c-jun is likely related to regenerative process while induction of NOS may be involved in the degenerative process.
Persistent Identifierhttp://hdl.handle.net/10722/149545
ISSN
2015 Impact Factor: 2.107
2015 SCImago Journal Rankings: 1.035
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWu, Wen_US
dc.contributor.authorLi, Yen_US
dc.contributor.authorSchinco, FPen_US
dc.date.accessioned2012-06-26T05:55:09Z-
dc.date.available2012-06-26T05:55:09Z-
dc.date.issued1994en_US
dc.identifier.citationNeuroscience Letters, 1994, v. 179 n. 1-2, p. 157-161en_US
dc.identifier.issn0304-3940en_US
dc.identifier.urihttp://hdl.handle.net/10722/149545-
dc.description.abstractExpression of neuronal NOS, c-jun and c-fos in spinal motoneurons following axonal damage were investigated in the present study. Although either distal spinal root axotomy or root avulsion induced expression of c-jun, expression of c-jun was predominantly found in distal root-axotomized motoneurons. In contrast, expression of NOS was exclusively observed in avulsed motoneurons. c-fos was not expressed in spinal motoneurons following either distal root axotomy or root avulsion. The different expression patterns of c-jun and NOS in the injured neurons suggest that these molecules may involve in different cellular processes and might play different roles in response to the injury. Since distal root axotomy did not cause motoneuron death and root avulsion did, expression of c-jun is likely related to regenerative process while induction of NOS may be involved in the degenerative process.en_US
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neuleten_US
dc.relation.ispartofNeuroscience Lettersen_US
dc.subject.meshAmino Acid Oxidoreductases - Biosynthesisen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAxons - Physiologyen_US
dc.subject.meshCell Death - Physiologyen_US
dc.subject.meshGenes, Junen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshMaleen_US
dc.subject.meshMotor Neurons - Enzymology - Metabolism - Physiologyen_US
dc.subject.meshNerve Regeneration - Physiologyen_US
dc.subject.meshNitric Oxide Synthaseen_US
dc.subject.meshProto-Oncogene Proteins C-Fos - Biosynthesisen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, Sprague-Dawleyen_US
dc.titleExpression of c-jun and neuronal nitric oxide synthase in rat spinal motoneurons following axonal injuryen_US
dc.typeArticleen_US
dc.identifier.emailWu, W:wtwu@hkucc.hku.hken_US
dc.identifier.authorityWu, W=rp00419en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0304-3940(94)90958-Xen_US
dc.identifier.pmid7531312en_US
dc.identifier.scopuseid_2-s2.0-0028145790en_US
dc.identifier.volume179en_US
dc.identifier.issue1-2en_US
dc.identifier.spage157en_US
dc.identifier.epage161en_US
dc.identifier.isiWOS:A1994PL51100039-
dc.publisher.placeIrelanden_US
dc.identifier.scopusauthoridWu, W=7407081122en_US
dc.identifier.scopusauthoridLi, Y=24298697800en_US
dc.identifier.scopusauthoridSchinco, FP=6506967600en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats