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Article: Ultrastructural and cytochemical studies of the effects of prolactin on the lateral prostate and the seminal vesicle of the castrated guinea pig

TitleUltrastructural and cytochemical studies of the effects of prolactin on the lateral prostate and the seminal vesicle of the castrated guinea pig
Authors
KeywordsGuinea pig (Dunkin Hartley)
Lateral prostate
Morphometry
Prolactin
Radioimmunoassay
Seminal vesicle
Thiamine pyrophosphatase
Issue Date1992
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00441/index.htm
Citation
Cell And Tissue Research, 1992, v. 270 n. 1, p. 105-112 How to Cite?
AbstractAdministration of ovine prolactin to castrated guinea pigs for 2 weeks induced hypertrophy of secretory cells in the lateral prostate when compared with the castrated controls. This was accompanied by an apparent increase in the number of profiles of granular endoplasmic reticulum and well developed Golgi complexes with dilated cisternae. An increase in the number of low-contrast electron-dense secretory granules was observed 4 weeks after prolactin treatment. In the seminal vesicle dilatation and degranulation of granular endoplasmic reticulum and an apparent decrease in the number of secretory granules were observed 4 weeks after prolactin administration. Following castration and 2 weeks after prolactin treatment, thiamine pyrophosphatase (TPPase)reaction product was mainly confined to 1-2 trans cisternae of the Golgi complexes in secretory cells of the lateral prostate and the seminal vesicle. In both glands, a reduction of TPPase activity was observed 2 weeks following prolactin administration, and the reaction product was totally absent after prolonged treatment for 4 weeks. The present study has provided morphological evidence that prolactin is capable of stimulating the secretory function of the lateral prostate while exerting some inhibitory effects on the seminal vesicle of the castrated guinea pig. In both glands, TPPase activity, and hence the process of glycosylation was inhibited after prolactin administration. The results from radioimmunoassay indicated that the action of prolactin on these glands could be a direct effect and not mediated through testosterone.
Persistent Identifierhttp://hdl.handle.net/10722/149522
ISSN
2015 Impact Factor: 2.948
2015 SCImago Journal Rankings: 1.539
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTam, CCen_HK
dc.contributor.authorWong, YCen_HK
dc.contributor.authorTang, Fen_HK
dc.date.accessioned2012-06-26T05:54:47Z-
dc.date.available2012-06-26T05:54:47Z-
dc.date.issued1992en_HK
dc.identifier.citationCell And Tissue Research, 1992, v. 270 n. 1, p. 105-112en_HK
dc.identifier.issn0302-766Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/149522-
dc.description.abstractAdministration of ovine prolactin to castrated guinea pigs for 2 weeks induced hypertrophy of secretory cells in the lateral prostate when compared with the castrated controls. This was accompanied by an apparent increase in the number of profiles of granular endoplasmic reticulum and well developed Golgi complexes with dilated cisternae. An increase in the number of low-contrast electron-dense secretory granules was observed 4 weeks after prolactin treatment. In the seminal vesicle dilatation and degranulation of granular endoplasmic reticulum and an apparent decrease in the number of secretory granules were observed 4 weeks after prolactin administration. Following castration and 2 weeks after prolactin treatment, thiamine pyrophosphatase (TPPase)reaction product was mainly confined to 1-2 trans cisternae of the Golgi complexes in secretory cells of the lateral prostate and the seminal vesicle. In both glands, a reduction of TPPase activity was observed 2 weeks following prolactin administration, and the reaction product was totally absent after prolonged treatment for 4 weeks. The present study has provided morphological evidence that prolactin is capable of stimulating the secretory function of the lateral prostate while exerting some inhibitory effects on the seminal vesicle of the castrated guinea pig. In both glands, TPPase activity, and hence the process of glycosylation was inhibited after prolactin administration. The results from radioimmunoassay indicated that the action of prolactin on these glands could be a direct effect and not mediated through testosterone.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00441/index.htmen_HK
dc.relation.ispartofCell and Tissue Researchen_HK
dc.subjectGuinea pig (Dunkin Hartley)en_HK
dc.subjectLateral prostateen_HK
dc.subjectMorphometryen_HK
dc.subjectProlactinen_HK
dc.subjectRadioimmunoassayen_HK
dc.subjectSeminal vesicleen_HK
dc.subjectThiamine pyrophosphataseen_HK
dc.subject.meshAnimalsen_US
dc.subject.meshBiological Markersen_US
dc.subject.meshGolgi Apparatus - Enzymologyen_US
dc.subject.meshGuinea Pigsen_US
dc.subject.meshMaleen_US
dc.subject.meshOrchiectomyen_US
dc.subject.meshProlactin - Pharmacologyen_US
dc.subject.meshProstate - Drug Effects - Secretion - Ultrastructureen_US
dc.subject.meshSeminal Vesicles - Drug Effects - Secretion - Ultrastructureen_US
dc.subject.meshThiamine Pyrophosphatase - Analysisen_US
dc.titleUltrastructural and cytochemical studies of the effects of prolactin on the lateral prostate and the seminal vesicle of the castrated guinea pigen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, YC: ycwong@hkucc.hku.hken_HK
dc.identifier.emailTang, F: ftang@hkucc.hku.hken_HK
dc.identifier.authorityWong, YC=rp00316en_HK
dc.identifier.authorityTang, F=rp00327en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/BF00381885en_HK
dc.identifier.pmid1423516-
dc.identifier.scopuseid_2-s2.0-0026699521en_HK
dc.identifier.volume270en_HK
dc.identifier.issue1en_HK
dc.identifier.spage105en_HK
dc.identifier.epage112en_HK
dc.identifier.isiWOS:A1992JP25300013-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridTam, CC=7201442974en_HK
dc.identifier.scopusauthoridWong, YC=7403041798en_HK
dc.identifier.scopusauthoridTang, F=7201979770en_HK

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