File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Morphometric and stereological analysis of the effects of 17β-estradiol on the glandular epithelium of the castrated guinea pig lateral prostate

TitleMorphometric and stereological analysis of the effects of 17β-estradiol on the glandular epithelium of the castrated guinea pig lateral prostate
Authors
Issue Date1991
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34304
Citation
Prostate, 1991, v. 19 n. 4, p. 279-297 How to Cite?
AbstractUpon administration of pharmacological doses of estradiol to castrated guinea pigs, the secretory cells of the lateral prostate underwent hypertrophy which resulted from significant increases in nuclear and cytoplasmic volume. There were quantitative increases in the small highly electron-dense granules and multivesicular bodies when compared with the castrated control. The dramatic increase in the number of highly electron-dense granules probably occurred at the expense of the low electron-dense granules. The average size of the condensing granules and mitochondria decreased significantly after estradiol administration. However, significant increase in the number of mitochondria was detected when compared with the castrated control. Ultrastructural data revealed no significant changes in the absolute dimensions of granular endoplasmic reticulum or of the Golgi complex, suggesting that estradiol exerted no significant stimulatory effects on these organelles. Pharmacological doses of estrogen appear to regulate the expression of secretory granules and multivesicular bodies in the lateral prostate of castrated guinea pigs.
Persistent Identifierhttp://hdl.handle.net/10722/149517
ISSN
2015 Impact Factor: 3.778
2015 SCImago Journal Rankings: 1.477
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTam, CCen_US
dc.contributor.authorWong, YCen_US
dc.contributor.authorWhite, FHen_US
dc.contributor.authorFowler, JPen_US
dc.date.accessioned2012-06-26T05:54:45Z-
dc.date.available2012-06-26T05:54:45Z-
dc.date.issued1991en_US
dc.identifier.citationProstate, 1991, v. 19 n. 4, p. 279-297en_US
dc.identifier.issn0270-4137en_US
dc.identifier.urihttp://hdl.handle.net/10722/149517-
dc.description.abstractUpon administration of pharmacological doses of estradiol to castrated guinea pigs, the secretory cells of the lateral prostate underwent hypertrophy which resulted from significant increases in nuclear and cytoplasmic volume. There were quantitative increases in the small highly electron-dense granules and multivesicular bodies when compared with the castrated control. The dramatic increase in the number of highly electron-dense granules probably occurred at the expense of the low electron-dense granules. The average size of the condensing granules and mitochondria decreased significantly after estradiol administration. However, significant increase in the number of mitochondria was detected when compared with the castrated control. Ultrastructural data revealed no significant changes in the absolute dimensions of granular endoplasmic reticulum or of the Golgi complex, suggesting that estradiol exerted no significant stimulatory effects on these organelles. Pharmacological doses of estrogen appear to regulate the expression of secretory granules and multivesicular bodies in the lateral prostate of castrated guinea pigs.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34304en_US
dc.relation.ispartofProstateen_US
dc.subject.meshAnimalsen_US
dc.subject.meshCytoplasmic Granules - Drug Effectsen_US
dc.subject.meshEpithelial Cellsen_US
dc.subject.meshEpithelium - Drug Effectsen_US
dc.subject.meshEstradiol - Pharmacologyen_US
dc.subject.meshGuinea Pigsen_US
dc.subject.meshMaleen_US
dc.subject.meshOrchiectomyen_US
dc.subject.meshProstate - Anatomy & Histology - Cytology - Drug Effectsen_US
dc.titleMorphometric and stereological analysis of the effects of 17β-estradiol on the glandular epithelium of the castrated guinea pig lateral prostateen_US
dc.typeArticleen_US
dc.identifier.emailWong, YC:ycwong@hkucc.hku.hken_US
dc.identifier.authorityWong, YC=rp00316en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1754518-
dc.identifier.scopuseid_2-s2.0-0026356261en_US
dc.identifier.volume19en_US
dc.identifier.issue4en_US
dc.identifier.spage279en_US
dc.identifier.epage297en_US
dc.identifier.isiWOS:A1991GW99700002-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridTam, CC=7201442974en_US
dc.identifier.scopusauthoridWong, YC=7403041798en_US
dc.identifier.scopusauthoridWhite, FH=7202578907en_US
dc.identifier.scopusauthoridFowler, JP=7402371064en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats