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Article: Glycoconjugates of the lateral prostate of the guinea pig: A lectin histochemical study

TitleGlycoconjugates of the lateral prostate of the guinea pig: A lectin histochemical study
Authors
Issue Date1991
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34304
Citation
Prostate, 1991, v. 19 n. 2, p. 155-172 How to Cite?
AbstractThe present study examined the glycoconjugates of the lateral prostate using a battery of lectins. The results indicated that the secretory epithelium was rich in mannose (Man), N-acetylglucosamine (GlcNAc), galactose (Gal), N-acetylgalactosamine (GalNAc), and complex oligosaccharides. Con A (concanavalin A), LCA (Lens culinaris agglutinin), PSA (Pisum sativum agglutinin), WGA (wheat germ agglutinin), PWM (pokeweed mitogen), RCA-I (Racinus communis isolectin I), and PHA-P (Phaseolus vulgaris agglutinin-P) reacted intensely with both epithelia and stroma, while SBA (soybean agglutinin) and PNA (peanut agglutinin), which bind to terminal Gal, GalNAc, and Gal β1,3 GalNAc appeared to be specific to the secretory epithelium. SBA and PNA were useful as markers in the study of the secretory function of the prostate gland. The present study has shown that the Golgi apparatus of prostatic epithelial cells was rich in fucose (Fuc), oligomers of GlcNAc, Gal β1,3 GalNAc, Gal, and Man containing glycoconjugates, indicating that the gland was actively involved in glycosylation. The present study has also shown that LTA (Lotus tetragonolobus agglutinin) is a good marker for the epithelial Golgi. PNA also bound to the epithelial basement membrane and the connective tissue in the lamina propria. The present study has thus established, for the first time, the glycoconjugate patterns in the lateral prostate of the guinea pig.
Persistent Identifierhttp://hdl.handle.net/10722/149513
ISSN
2015 Impact Factor: 3.778
2015 SCImago Journal Rankings: 1.477
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, Len_US
dc.contributor.authorWong, YCen_US
dc.date.accessioned2012-06-26T05:54:42Z-
dc.date.available2012-06-26T05:54:42Z-
dc.date.issued1991en_US
dc.identifier.citationProstate, 1991, v. 19 n. 2, p. 155-172en_US
dc.identifier.issn0270-4137en_US
dc.identifier.urihttp://hdl.handle.net/10722/149513-
dc.description.abstractThe present study examined the glycoconjugates of the lateral prostate using a battery of lectins. The results indicated that the secretory epithelium was rich in mannose (Man), N-acetylglucosamine (GlcNAc), galactose (Gal), N-acetylgalactosamine (GalNAc), and complex oligosaccharides. Con A (concanavalin A), LCA (Lens culinaris agglutinin), PSA (Pisum sativum agglutinin), WGA (wheat germ agglutinin), PWM (pokeweed mitogen), RCA-I (Racinus communis isolectin I), and PHA-P (Phaseolus vulgaris agglutinin-P) reacted intensely with both epithelia and stroma, while SBA (soybean agglutinin) and PNA (peanut agglutinin), which bind to terminal Gal, GalNAc, and Gal β1,3 GalNAc appeared to be specific to the secretory epithelium. SBA and PNA were useful as markers in the study of the secretory function of the prostate gland. The present study has shown that the Golgi apparatus of prostatic epithelial cells was rich in fucose (Fuc), oligomers of GlcNAc, Gal β1,3 GalNAc, Gal, and Man containing glycoconjugates, indicating that the gland was actively involved in glycosylation. The present study has also shown that LTA (Lotus tetragonolobus agglutinin) is a good marker for the epithelial Golgi. PNA also bound to the epithelial basement membrane and the connective tissue in the lamina propria. The present study has thus established, for the first time, the glycoconjugate patterns in the lateral prostate of the guinea pig.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/34304en_US
dc.relation.ispartofProstateen_US
dc.subject.meshAcetylgalactosamine - Biosynthesisen_US
dc.subject.meshAcetylglucosamine - Biosynthesisen_US
dc.subject.meshAgglutinins - Diagnostic Useen_US
dc.subject.meshAnimalsen_US
dc.subject.meshConcanavalin A - Diagnostic Useen_US
dc.subject.meshEpithelium - Metabolismen_US
dc.subject.meshExtracellular Matrix - Chemistryen_US
dc.subject.meshGalactose - Biosynthesisen_US
dc.subject.meshGlycoconjugates - Analysisen_US
dc.subject.meshGuinea Pigsen_US
dc.subject.meshImmunohistochemistryen_US
dc.subject.meshLectins - Diagnostic Useen_US
dc.subject.meshMaleen_US
dc.subject.meshMannose - Biosynthesisen_US
dc.subject.meshPlant Lectinsen_US
dc.subject.meshPokeweed Mitogens - Diagnostic Useen_US
dc.subject.meshProstate - Metabolismen_US
dc.titleGlycoconjugates of the lateral prostate of the guinea pig: A lectin histochemical studyen_US
dc.typeArticleen_US
dc.identifier.emailWong, YC:ycwong@hkucc.hku.hken_US
dc.identifier.authorityWong, YC=rp00316en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1923963en_US
dc.identifier.scopuseid_2-s2.0-0026048584en_US
dc.identifier.volume19en_US
dc.identifier.issue2en_US
dc.identifier.spage155en_US
dc.identifier.epage172en_US
dc.identifier.isiWOS:A1991GW40600008-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridChan, L=35336076700en_US
dc.identifier.scopusauthoridWong, YC=7403041798en_US

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