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- Publisher Website: 10.1016/0006-291X(90)90908-6
- Scopus: eid_2-s2.0-0025095483
- PMID: 2302251
- WOS: WOS:A1990CL74100065
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Article: cDNA cloning of a novel cell adhesion protein expressed in human squamous carcinoma cells
Title | cDNA cloning of a novel cell adhesion protein expressed in human squamous carcinoma cells |
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Authors | |
Issue Date | 1990 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/description |
Citation | Biochemical And Biophysical Research Communications, 1990, v. 166 n. 2, p. 984-992 How to Cite? |
Abstract | A novel protein (SQM1 protein) present in human squamous epithelial cells has been found to be involved in cell adhesion in squamous epithelial cells, endothelial cells and extracellular matrix proteins. The corresponding cDNA that encodes a 135-residue polypeptide has been isolated. Sequence analysis indicates that the encoded polypeptide is distinct yet related to the β subunit of integrins. A new sequence motif consisting of a heptadic repeat of positively-charged residues present in the polypeptide has been identified and is proposed to be important in protein-protein interaction. These results suggest that SQM1 protein, a new cell adhesion molecule expressed in squamous epithelial cells, may play an important role in tumor metastasis. |
Persistent Identifier | http://hdl.handle.net/10722/149501 |
ISSN | 2023 Impact Factor: 2.5 2023 SCImago Journal Rankings: 0.770 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Wong, YC | en_US |
dc.contributor.author | Tsao, SW | en_US |
dc.contributor.author | Kakefuda, M | en_US |
dc.contributor.author | Bernal, SD | en_US |
dc.date.accessioned | 2012-06-26T05:54:35Z | - |
dc.date.available | 2012-06-26T05:54:35Z | - |
dc.date.issued | 1990 | en_US |
dc.identifier.citation | Biochemical And Biophysical Research Communications, 1990, v. 166 n. 2, p. 984-992 | en_US |
dc.identifier.issn | 0006-291X | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/149501 | - |
dc.description.abstract | A novel protein (SQM1 protein) present in human squamous epithelial cells has been found to be involved in cell adhesion in squamous epithelial cells, endothelial cells and extracellular matrix proteins. The corresponding cDNA that encodes a 135-residue polypeptide has been isolated. Sequence analysis indicates that the encoded polypeptide is distinct yet related to the β subunit of integrins. A new sequence motif consisting of a heptadic repeat of positively-charged residues present in the polypeptide has been identified and is proposed to be important in protein-protein interaction. These results suggest that SQM1 protein, a new cell adhesion molecule expressed in squamous epithelial cells, may play an important role in tumor metastasis. | en_US |
dc.language | eng | en_US |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/wps/find/journaldescription.cws_home/622790/description | en_US |
dc.relation.ispartof | Biochemical and Biophysical Research Communications | en_US |
dc.subject.mesh | Amino Acid Sequence | en_US |
dc.subject.mesh | Antibodies, Monoclonal - Immunology | en_US |
dc.subject.mesh | Base Sequence | en_US |
dc.subject.mesh | Blotting, Northern | en_US |
dc.subject.mesh | Blotting, Western | en_US |
dc.subject.mesh | Carcinoma, Squamous Cell - Genetics | en_US |
dc.subject.mesh | Cell Adhesion | en_US |
dc.subject.mesh | Cell Adhesion Molecules - Genetics - Immunology | en_US |
dc.subject.mesh | Cloning, Molecular | en_US |
dc.subject.mesh | Dna - Genetics | en_US |
dc.subject.mesh | Epithelium - Analysis | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Molecular Sequence Data | en_US |
dc.subject.mesh | Nadh, Nadph Oxidoreductases | en_US |
dc.subject.mesh | Neoplasm Proteins - Genetics - Immunology | en_US |
dc.subject.mesh | Protein Biosynthesis | en_US |
dc.subject.mesh | Tumor Cells, Cultured | en_US |
dc.title | cDNA cloning of a novel cell adhesion protein expressed in human squamous carcinoma cells | en_US |
dc.type | Article | en_US |
dc.identifier.email | Tsao, SW:gswtsao@hkucc.hku.hk | en_US |
dc.identifier.authority | Tsao, SW=rp00399 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0006-291X(90)90908-6 | en_US |
dc.identifier.pmid | 2302251 | - |
dc.identifier.scopus | eid_2-s2.0-0025095483 | en_US |
dc.identifier.volume | 166 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 984 | en_US |
dc.identifier.epage | 992 | en_US |
dc.identifier.isi | WOS:A1990CL74100065 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Wong, YC=7403041461 | en_US |
dc.identifier.scopusauthorid | Tsao, SW=7102813116 | en_US |
dc.identifier.scopusauthorid | Kakefuda, M=6506142302 | en_US |
dc.identifier.scopusauthorid | Bernal, SD=7006000150 | en_US |
dc.identifier.issnl | 0006-291X | - |