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Article: Regeneration of retinal axons in grafts of peripheral and central nervous tissue in the adult rat

TitleRegeneration of retinal axons in grafts of peripheral and central nervous tissue in the adult rat
Authors
Issue Date1990
PublisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neulet
Citation
Neuroscience Letters, 1990, v. 117 n. 1-2, p. 14-19 How to Cite?
AbstractPeripheral nerves were autologously grafted to the retinae of adult rats. The distal end of the nerves was inserted into fetal tectal tissue placed within cortical lesion cavities. Two to 8 months later, anterograde pathway tracing using horseradish peroxidase demonstrated retinal axons regenerating along the length of the PNS nerve graft in 87% of animals with viable PNS and fetal tectal grafts. Of these animals, retinal axons grew into the tectal neuropil in 23% of cases but specific innervation of appropriate target regions was not detected.
Persistent Identifierhttp://hdl.handle.net/10722/149499
ISSN
2015 Impact Factor: 2.107
2015 SCImago Journal Rankings: 1.035
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTan, MMLen_US
dc.contributor.authorHarvey, ARen_US
dc.contributor.authorSo, KFen_US
dc.date.accessioned2012-06-26T05:54:33Z-
dc.date.available2012-06-26T05:54:33Z-
dc.date.issued1990en_US
dc.identifier.citationNeuroscience Letters, 1990, v. 117 n. 1-2, p. 14-19en_US
dc.identifier.issn0304-3940en_US
dc.identifier.urihttp://hdl.handle.net/10722/149499-
dc.description.abstractPeripheral nerves were autologously grafted to the retinae of adult rats. The distal end of the nerves was inserted into fetal tectal tissue placed within cortical lesion cavities. Two to 8 months later, anterograde pathway tracing using horseradish peroxidase demonstrated retinal axons regenerating along the length of the PNS nerve graft in 87% of animals with viable PNS and fetal tectal grafts. Of these animals, retinal axons grew into the tectal neuropil in 23% of cases but specific innervation of appropriate target regions was not detected.en_US
dc.languageengen_US
dc.publisherElsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/neuleten_US
dc.relation.ispartofNeuroscience Lettersen_US
dc.subject.meshAcetylcholinesterase - Metabolismen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAxons - Physiologyen_US
dc.subject.meshFetal Tissue Transplantation - Physiologyen_US
dc.subject.meshNerve Regenerationen_US
dc.subject.meshOptic Nerve - Physiologyen_US
dc.subject.meshRatsen_US
dc.subject.meshRetinaen_US
dc.subject.meshSciatic Nerve - Transplantationen_US
dc.subject.meshSuperior Colliculi - Transplantationen_US
dc.subject.meshTransplantation, Autologousen_US
dc.titleRegeneration of retinal axons in grafts of peripheral and central nervous tissue in the adult raten_US
dc.typeArticleen_US
dc.identifier.emailSo, KF:hrmaskf@hkucc.hku.hken_US
dc.identifier.authoritySo, KF=rp00329en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0304-3940(90)90112-Men_US
dc.identifier.pmid2290608-
dc.identifier.scopuseid_2-s2.0-0025051196en_US
dc.identifier.volume117en_US
dc.identifier.issue1-2en_US
dc.identifier.spage14en_US
dc.identifier.epage19en_US
dc.identifier.isiWOS:A1990DZ85400003-
dc.publisher.placeIrelanden_US
dc.identifier.scopusauthoridTan, MML=7401464751en_US
dc.identifier.scopusauthoridHarvey, AR=7402410218en_US
dc.identifier.scopusauthoridSo, KF=34668391300en_US

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