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Conference Paper: Effects of calcium phosphate nanocrystals on osseointegration in irradiated animal

TitleEffects of calcium phosphate nanocrystals on osseointegration in irradiated animal
Authors
KeywordsAnimal
Bone
Implants
Radiation
Issue Date2011
PublisherThe International Association for Dental Research.
Citation
The 25th Annual Scientific Meeting of the IADR-SEA Division and the 22nd Annual Meeting of SEAADE, Singapore, 28-30 October 2011. How to Cite?
AbstractOBJECTIVES: To evaluate the effect of discrete calcium phosphate nanocrystal modification of implant on osseointegration in irradiation compromised animal model. MATERIALS AND METHODS: Sixteen adult New Zealand White rabbits were randomly divided into NanoTite (discrete calcium phosphate nanocrystal modification) and OsseoTite (control) groups. The left leg of rabbits received 15Gy radiation. One week after radiation, two implants were placed in the irradiated leg of each rabbit. Implant stability quotient (ISQ) were measured immediately. Four rabbits in each group were sacrificed at 4 week and 12 week respectively. ISQ was measured again before sacrifice. Osseointegration was assessed using micro-CT with the ratio of bone volume to total volume (BV/TV). RESULTS: Fourteen animals completed experiment. No inflammation and mobility were detected. There was no statistical difference in ISQ values at week 4 between two groups. At week 12, NanoTite group showed a significantly higher ISQ value than the control group. BV/TV in NanoTite group was significantly higher than that in the control group at week 4 and week 12. CONCLUSION: The discrete calcium phosphate nanocrystal modification on the implant surface can enhance the osseointegration in the irradiated rabbit model.
DescriptionPoster Discussion Session: 16. Senior Researcher Division Travel Award: paper no. 89
Persistent Identifierhttp://hdl.handle.net/10722/149195

 

DC FieldValueLanguage
dc.contributor.authorLi, Jen_US
dc.contributor.authorPow, EHNen_US
dc.contributor.authorCheung, LKen_US
dc.contributor.authorZheng, Len_US
dc.contributor.authorKwong, DLWen_US
dc.date.accessioned2012-06-22T06:29:36Z-
dc.date.available2012-06-22T06:29:36Z-
dc.date.issued2011en_US
dc.identifier.citationThe 25th Annual Scientific Meeting of the IADR-SEA Division and the 22nd Annual Meeting of SEAADE, Singapore, 28-30 October 2011.en_US
dc.identifier.urihttp://hdl.handle.net/10722/149195-
dc.descriptionPoster Discussion Session: 16. Senior Researcher Division Travel Award: paper no. 89-
dc.description.abstractOBJECTIVES: To evaluate the effect of discrete calcium phosphate nanocrystal modification of implant on osseointegration in irradiation compromised animal model. MATERIALS AND METHODS: Sixteen adult New Zealand White rabbits were randomly divided into NanoTite (discrete calcium phosphate nanocrystal modification) and OsseoTite (control) groups. The left leg of rabbits received 15Gy radiation. One week after radiation, two implants were placed in the irradiated leg of each rabbit. Implant stability quotient (ISQ) were measured immediately. Four rabbits in each group were sacrificed at 4 week and 12 week respectively. ISQ was measured again before sacrifice. Osseointegration was assessed using micro-CT with the ratio of bone volume to total volume (BV/TV). RESULTS: Fourteen animals completed experiment. No inflammation and mobility were detected. There was no statistical difference in ISQ values at week 4 between two groups. At week 12, NanoTite group showed a significantly higher ISQ value than the control group. BV/TV in NanoTite group was significantly higher than that in the control group at week 4 and week 12. CONCLUSION: The discrete calcium phosphate nanocrystal modification on the implant surface can enhance the osseointegration in the irradiated rabbit model.-
dc.languageengen_US
dc.publisherThe International Association for Dental Research.-
dc.relation.ispartofIADR/SEAADE Annual Scientific Meeting, 2011en_US
dc.subjectAnimal-
dc.subjectBone-
dc.subjectImplants-
dc.subjectRadiation-
dc.titleEffects of calcium phosphate nanocrystals on osseointegration in irradiated animalen_US
dc.typeConference_Paperen_US
dc.identifier.emailLi, J: jyli@HKUSUC.hku.hken_US
dc.identifier.emailPow, EHN: ehnpow@hku.hken_US
dc.identifier.emailCheung, LK: lkcheung@hkucc.hku.hken_US
dc.identifier.emailZheng, L: lwzheng@hku.hken_US
dc.identifier.emailKwong, DLW: dlwkwong@hku.hk-
dc.identifier.authorityPow, EHN=rp00030en_US
dc.identifier.authorityCheung, LK=rp00013en_US
dc.identifier.authorityZheng, L=rp01411en_US
dc.identifier.authorityKwong, DLW=rp00414en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros200391en_US
dc.publisher.placeUnited States-
dc.description.otherThe 25th Annual Scientific Meeting of the IADR-SEA Division and the 22nd Annual Meeting of SEAADE, Singapore, 28-30 October 2011.-

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