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Article: Effects of prehypertension and hypertension subtype on cardiovascular disease in the Asia-Pacific region

TitleEffects of prehypertension and hypertension subtype on cardiovascular disease in the Asia-Pacific region
Authors
KeywordsPrehypertension
Hypertension
Hypertension subtype
Isolated diastolic hypertension
Cardiovascular disease
Coronary heart disease
Stroke
Issue Date2012
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.shef-ac-press.co.uk
Citation
Hypertension, 2012, v. 59 n. 6, p. 1118-1123 How to Cite?
AbstractThe Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure defined blood pressure (BP) levels of 120 to 139/80 to 89 mm Hg as prehypertension and those of ≥140/90 mm Hg as hypertension. Hypertension can be divided into 3 categories, isolated diastolic (IDH; systolic BP <140 mm Hg and diastolic BP ≥90 mmHg), isolated systolic (systolic BP ≥140 mm Hg and diastolic BP <90 mmHg), and systolic-diastolic hypertension (systolic BP ≥140 mm Hg and diastolic BP ≥90 mmHg). Although there is clear evidence that isolated systolic hypertension and systolic-diastolic hypertension increase the risks of future vascular events, there remains uncertainty about the effects of IDH. The objective was to determine the effects of prehypertension and hypertension subtypes (IDH, isolated systolic hypertension, and systolic-diastolic hypertension) on the risks of cardiovascular disease (CVD) in the Asia-Pacific Region. The Asia Pacific Cohort Studies Collaboration is an individual participant data overview of cohort studies in the region. This analysis included a total of 346570 participants from 36 cohort studies. Outcomes were fatal and nonfatal CVD. The relationship between BP categories and CVD was explored using a Cox proportional hazards model adjusted for age, cholesterol, and smoking and stratified by sex and study. Compared with normal BP (<120/80 mmHg), hazard ratios (95% CIs) for CVD were 1.41 (1.31-1.53) for prehypertension, 1.81 (1.61-2.04) for IDH, 2.18 (2.00-2.37) for isolated systolic hypertension, and 3.42 (3.17-3.70) for systolic-diastolic hypertension. Separately significant effects of prehypertension and hypertension subtypes were also observed for coronary heart disease, ischemic stroke, and hemorrhagic stroke. In the Asia-Pacific region, prehypertension and all hypertension subtypes, including IDH, thus clearly predicted increased risks of CVD. © 2012 American Heart Association, Inc.
Persistent Identifierhttp://hdl.handle.net/10722/149169
ISSN
2015 Impact Factor: 6.294
2015 SCImago Journal Rankings: 3.702
ISI Accession Number ID
Funding AgencyGrant Number
National Health and Medical Research Council of Australia358395
Ministry of Health and Welfare, Republic of KoreaA102065
Australian Research Council
Funding Information:

This study was supported by a National Health and Medical Research Council of Australia program grant (358395). The study in Korea was supported by a grant of the Korea Healthcare Technology Research and Development Project of the Ministry of Health and Welfare, Republic of Korea (A102065). H. A. holds an Australian Research Council Future Fellowship.

 

DC FieldValueLanguage
dc.contributor.authorArima, Hen_US
dc.contributor.authorMurakami, Yen_US
dc.contributor.authorLam, THen_US
dc.contributor.authorKim, HCen_US
dc.contributor.authorUeshima, Hen_US
dc.contributor.authorWoo, Jen_US
dc.contributor.authorSuh, Ien_US
dc.contributor.authorFang, XHen_US
dc.contributor.authorWoodward, Men_US
dc.date.accessioned2012-06-22T06:27:43Z-
dc.date.available2012-06-22T06:27:43Z-
dc.date.issued2012en_US
dc.identifier.citationHypertension, 2012, v. 59 n. 6, p. 1118-1123en_US
dc.identifier.issn0194-911X-
dc.identifier.urihttp://hdl.handle.net/10722/149169-
dc.description.abstractThe Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure defined blood pressure (BP) levels of 120 to 139/80 to 89 mm Hg as prehypertension and those of ≥140/90 mm Hg as hypertension. Hypertension can be divided into 3 categories, isolated diastolic (IDH; systolic BP <140 mm Hg and diastolic BP ≥90 mmHg), isolated systolic (systolic BP ≥140 mm Hg and diastolic BP <90 mmHg), and systolic-diastolic hypertension (systolic BP ≥140 mm Hg and diastolic BP ≥90 mmHg). Although there is clear evidence that isolated systolic hypertension and systolic-diastolic hypertension increase the risks of future vascular events, there remains uncertainty about the effects of IDH. The objective was to determine the effects of prehypertension and hypertension subtypes (IDH, isolated systolic hypertension, and systolic-diastolic hypertension) on the risks of cardiovascular disease (CVD) in the Asia-Pacific Region. The Asia Pacific Cohort Studies Collaboration is an individual participant data overview of cohort studies in the region. This analysis included a total of 346570 participants from 36 cohort studies. Outcomes were fatal and nonfatal CVD. The relationship between BP categories and CVD was explored using a Cox proportional hazards model adjusted for age, cholesterol, and smoking and stratified by sex and study. Compared with normal BP (<120/80 mmHg), hazard ratios (95% CIs) for CVD were 1.41 (1.31-1.53) for prehypertension, 1.81 (1.61-2.04) for IDH, 2.18 (2.00-2.37) for isolated systolic hypertension, and 3.42 (3.17-3.70) for systolic-diastolic hypertension. Separately significant effects of prehypertension and hypertension subtypes were also observed for coronary heart disease, ischemic stroke, and hemorrhagic stroke. In the Asia-Pacific region, prehypertension and all hypertension subtypes, including IDH, thus clearly predicted increased risks of CVD. © 2012 American Heart Association, Inc.-
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.shef-ac-press.co.uk-
dc.relation.ispartofHypertensionen_US
dc.subjectPrehypertension-
dc.subjectHypertension-
dc.subjectHypertension subtype-
dc.subjectIsolated diastolic hypertension-
dc.subjectCardiovascular disease-
dc.subjectCoronary heart disease-
dc.subjectStroke-
dc.subject.meshCardiovascular Diseases - epidemiology - etiology-
dc.subject.meshHealth Surveys - statistics and numerical data-
dc.subject.meshHypertension - complications - epidemiology-
dc.subject.meshPrehypertension - complications - epidemiology-
dc.subject.meshProportional Hazards Models-
dc.subject.meshOceania - epidemiology-
dc.subject.meshRisk Assessment - statistics and numerical data-
dc.titleEffects of prehypertension and hypertension subtype on cardiovascular disease in the Asia-Pacific regionen_US
dc.typeArticleen_US
dc.identifier.emailLam, TH: hrmrlth@hku.hken_US
dc.identifier.emailWoodward, M: markw@georgeinstitute.org.au-
dc.identifier.authorityLam, TH=rp00326en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1161/HYPERTENSIONAHA.111.187252-
dc.identifier.pmid22547441-
dc.identifier.scopuseid_2-s2.0-84861529123-
dc.identifier.hkuros199920en_US
dc.identifier.volume59en_US
dc.identifier.issue6en_US
dc.identifier.spage1118en_US
dc.identifier.epage1123en_US
dc.identifier.isiWOS:000305176300016-
dc.publisher.placeUnited States-

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