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Conference Paper: An interstitial fluid transdermal extraction, collection and measurement system
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TitleAn interstitial fluid transdermal extraction, collection and measurement system
 
AuthorsYu, H2
Li, D2
Xu, K2
Roberts, RC1
Tien, NC1
 
KeywordsContinuous Glucose Monitoring
Flow Sensor
Interstitial Fluid
PDMS
Venturi Tube
 
Issue Date2011
 
CitationNems 2011 - 6Th Ieee International Conference On Nano/Micro Engineered And Molecular Systems, 2011, p. 1237-1240 [How to Cite?]
DOI: http://dx.doi.org/10.1109/NEMS.2011.6017581
 
AbstractWe present a new microfluidic system for transdermal interstitial fluid (ISF) extraction, collection, and volumetric measurement towards the application of noninvasive, continuous, and real-time glucose monitoring. This device consists of a Venturi Tube for vacuum generation, chambers for the introduction of ISF and normal saline solution, pneumatic valves for fluid control, and flow sensors for ISF and normal saline solution volumetric measurement. Under the control of pneumatic valves, demonstration of the normal saline injection, ISF extraction and collection functions of the system is presented using the stable vacuum generated by the integrated Venturi structure. A test volume of deionized water is measured using the flow sensor, and the measurement results are compared with the values measured by micro syringe. The data correlates well with each other (R 2=0.9952). © 2011 IEEE.
 
DOIhttp://dx.doi.org/10.1109/NEMS.2011.6017581
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorYu, H
 
dc.contributor.authorLi, D
 
dc.contributor.authorXu, K
 
dc.contributor.authorRoberts, RC
 
dc.contributor.authorTien, NC
 
dc.date.accessioned2012-06-20T06:18:01Z
 
dc.date.available2012-06-20T06:18:01Z
 
dc.date.issued2011
 
dc.description.abstractWe present a new microfluidic system for transdermal interstitial fluid (ISF) extraction, collection, and volumetric measurement towards the application of noninvasive, continuous, and real-time glucose monitoring. This device consists of a Venturi Tube for vacuum generation, chambers for the introduction of ISF and normal saline solution, pneumatic valves for fluid control, and flow sensors for ISF and normal saline solution volumetric measurement. Under the control of pneumatic valves, demonstration of the normal saline injection, ISF extraction and collection functions of the system is presented using the stable vacuum generated by the integrated Venturi structure. A test volume of deionized water is measured using the flow sensor, and the measurement results are compared with the values measured by micro syringe. The data correlates well with each other (R 2=0.9952). © 2011 IEEE.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationNems 2011 - 6Th Ieee International Conference On Nano/Micro Engineered And Molecular Systems, 2011, p. 1237-1240 [How to Cite?]
DOI: http://dx.doi.org/10.1109/NEMS.2011.6017581
 
dc.identifier.doihttp://dx.doi.org/10.1109/NEMS.2011.6017581
 
dc.identifier.epage1240
 
dc.identifier.scopuseid_2-s2.0-80053295704
 
dc.identifier.spage1237
 
dc.identifier.urihttp://hdl.handle.net/10722/149036
 
dc.languageeng
 
dc.relation.ispartofNEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
 
dc.relation.referencesReferences in Scopus
 
dc.subjectContinuous Glucose Monitoring
 
dc.subjectFlow Sensor
 
dc.subjectInterstitial Fluid
 
dc.subjectPDMS
 
dc.subjectVenturi Tube
 
dc.titleAn interstitial fluid transdermal extraction, collection and measurement system
 
dc.typeConference_Paper
 
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Author Affiliations
  1. Case Western Reserve University
  2. Tianjin University