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Article: Design, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system

TitleDesign, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system
Authors
Yu, HLi, DRoberts, RCXu, KTien, NC
Issue Date2012
PublisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/jmm
Citation
Journal Of Micromechanics And Microengineering, 2012, v. 22 n. 3, article no. 035010 How to Cite?
DOI: http://dx.doi.org/10.1088/0960-1317/22/3/035010
AbstractIn this paper, a micro-Venturi tube fabricated with polydimethylsiloxane (PDMS) is studied for interstitial fluid (ISF) transdermal extraction and fluid manipulation in a microfluidic system toward the application of continuous glucose monitoring. The fabrication structure parameters of the PDMS Venturi tube were theoretically analyzed and experimentally validated against the output vacuum efficiency of the Venturi structure. The optimization methods of the Venturi structure were also discussed. In addition, an optimized micro-Venturi structure was proposed and fabricated. A vacuum pressure of less than 86 kPa had been achieved when an external pressure of 240 kPa was applied to this optimized Venturi tube. Both experimental and mathematical results demonstrate the potential applicability of the micro-Venturi tube in ISF transdermal extraction and fluid manipulation. © 2012 IOP Publishing Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/148958
ISSN
0960-1317
2023 Impact Factor: 2.4
2023 SCImago Journal Rankings: 0.476
ISI Accession Number ID
WOS:000301171300010
Funding AgencyGrant Number
National Natural Science Foundation of China30800239
60938002
61176107
Key Projects in the Science & Technology Pillar Program of Tianjin11ZCKFSY01500
Innovation Foundation of Tianjin University
Funding Information:

This work is supported by the National Natural Science Foundation of China (no. 30800239, no. 60938002 and no. 61176107), the Key Projects in the Science & Technology Pillar Program of Tianjin (no. 11ZCKFSY01500) and the Innovation Foundation of Tianjin University.

References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorYu, Hen_HK
dc.contributor.authorLi, Den_HK
dc.contributor.authorRoberts, RCen_HK
dc.contributor.authorXu, Ken_HK
dc.contributor.authorTien, NCen_HK
dc.date.accessioned2012-06-20T06:17:04Z-
dc.date.available2012-06-20T06:17:04Z-
dc.date.issued2012en_HK
dc.identifier.citationJournal Of Micromechanics And Microengineering, 2012, v. 22 n. 3, article no. 035010en_HK
dc.identifier.issn0960-1317en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148958-
dc.description.abstractIn this paper, a micro-Venturi tube fabricated with polydimethylsiloxane (PDMS) is studied for interstitial fluid (ISF) transdermal extraction and fluid manipulation in a microfluidic system toward the application of continuous glucose monitoring. The fabrication structure parameters of the PDMS Venturi tube were theoretically analyzed and experimentally validated against the output vacuum efficiency of the Venturi structure. The optimization methods of the Venturi structure were also discussed. In addition, an optimized micro-Venturi structure was proposed and fabricated. A vacuum pressure of less than 86 kPa had been achieved when an external pressure of 240 kPa was applied to this optimized Venturi tube. Both experimental and mathematical results demonstrate the potential applicability of the micro-Venturi tube in ISF transdermal extraction and fluid manipulation. © 2012 IOP Publishing Ltd.en_HK
dc.languageengen_US
dc.publisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/jmmen_HK
dc.relation.ispartofJournal of Micromechanics and Microengineeringen_HK
dc.titleDesign, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic systemen_HK
dc.typeArticleen_HK
dc.identifier.emailRoberts, RC: rcr8@hku.hken_HK
dc.identifier.authorityRoberts, RC=rp01738en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1088/0960-1317/22/3/035010en_HK
dc.identifier.scopuseid_2-s2.0-84863281493en_HK
dc.identifier.hkuros222875-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84863281493&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume22en_HK
dc.identifier.issue3en_HK
dc.identifier.eissn1361-6439-
dc.identifier.isiWOS:000301171300010-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridYu, H=16240359300en_HK
dc.identifier.scopusauthoridLi, D=8432738800en_HK
dc.identifier.scopusauthoridRoberts, RC=24466830100en_HK
dc.identifier.scopusauthoridXu, K=7403282051en_HK
dc.identifier.scopusauthoridTien, NC=55277995000en_HK
dc.identifier.issnl0960-1317-

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