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Article: Design, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system
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TitleDesign, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system
 
AuthorsYu, H2 1
Li, D2
Roberts, RC1
Xu, K2
Tien, NC1
 
Issue Date2012
 
PublisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/jmm
 
CitationJournal Of Micromechanics And Microengineering, 2012, v. 22 n. 3, article no. 035010 [How to Cite?]
DOI: http://dx.doi.org/10.1088/0960-1317/22/3/035010
 
AbstractIn this paper, a micro-Venturi tube fabricated with polydimethylsiloxane (PDMS) is studied for interstitial fluid (ISF) transdermal extraction and fluid manipulation in a microfluidic system toward the application of continuous glucose monitoring. The fabrication structure parameters of the PDMS Venturi tube were theoretically analyzed and experimentally validated against the output vacuum efficiency of the Venturi structure. The optimization methods of the Venturi structure were also discussed. In addition, an optimized micro-Venturi structure was proposed and fabricated. A vacuum pressure of less than 86 kPa had been achieved when an external pressure of 240 kPa was applied to this optimized Venturi tube. Both experimental and mathematical results demonstrate the potential applicability of the micro-Venturi tube in ISF transdermal extraction and fluid manipulation. © 2012 IOP Publishing Ltd.
 
ISSN0960-1317
2012 Impact Factor: 1.79
2012 SCImago Journal Rankings: 0.829
 
DOIhttp://dx.doi.org/10.1088/0960-1317/22/3/035010
 
ISI Accession Number IDWOS:000301171300010
Funding AgencyGrant Number
National Natural Science Foundation of China30800239
60938002
61176107
Key Projects in the Science & Technology Pillar Program of Tianjin11ZCKFSY01500
Innovation Foundation of Tianjin University
Funding Information:

This work is supported by the National Natural Science Foundation of China (no. 30800239, no. 60938002 and no. 61176107), the Key Projects in the Science & Technology Pillar Program of Tianjin (no. 11ZCKFSY01500) and the Innovation Foundation of Tianjin University.

 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorYu, H
 
dc.contributor.authorLi, D
 
dc.contributor.authorRoberts, RC
 
dc.contributor.authorXu, K
 
dc.contributor.authorTien, NC
 
dc.date.accessioned2012-06-20T06:17:04Z
 
dc.date.available2012-06-20T06:17:04Z
 
dc.date.issued2012
 
dc.description.abstractIn this paper, a micro-Venturi tube fabricated with polydimethylsiloxane (PDMS) is studied for interstitial fluid (ISF) transdermal extraction and fluid manipulation in a microfluidic system toward the application of continuous glucose monitoring. The fabrication structure parameters of the PDMS Venturi tube were theoretically analyzed and experimentally validated against the output vacuum efficiency of the Venturi structure. The optimization methods of the Venturi structure were also discussed. In addition, an optimized micro-Venturi structure was proposed and fabricated. A vacuum pressure of less than 86 kPa had been achieved when an external pressure of 240 kPa was applied to this optimized Venturi tube. Both experimental and mathematical results demonstrate the potential applicability of the micro-Venturi tube in ISF transdermal extraction and fluid manipulation. © 2012 IOP Publishing Ltd.
 
dc.description.natureLink_to_subscribed_fulltext
 
dc.identifier.citationJournal Of Micromechanics And Microengineering, 2012, v. 22 n. 3, article no. 035010 [How to Cite?]
DOI: http://dx.doi.org/10.1088/0960-1317/22/3/035010
 
dc.identifier.doihttp://dx.doi.org/10.1088/0960-1317/22/3/035010
 
dc.identifier.eissn1361-6439
 
dc.identifier.hkuros222875
 
dc.identifier.isiWOS:000301171300010
Funding AgencyGrant Number
National Natural Science Foundation of China30800239
60938002
61176107
Key Projects in the Science & Technology Pillar Program of Tianjin11ZCKFSY01500
Innovation Foundation of Tianjin University
Funding Information:

This work is supported by the National Natural Science Foundation of China (no. 30800239, no. 60938002 and no. 61176107), the Key Projects in the Science & Technology Pillar Program of Tianjin (no. 11ZCKFSY01500) and the Innovation Foundation of Tianjin University.

 
dc.identifier.issn0960-1317
2012 Impact Factor: 1.79
2012 SCImago Journal Rankings: 0.829
 
dc.identifier.issue3
 
dc.identifier.scopuseid_2-s2.0-84863281493
 
dc.identifier.urihttp://hdl.handle.net/10722/148958
 
dc.identifier.volume22
 
dc.languageeng
 
dc.publisherInstitute of Physics Publishing. The Journal's web site is located at http://www.iop.org/journals/jmm
 
dc.publisher.placeUnited Kingdom
 
dc.relation.ispartofJournal of Micromechanics and Microengineering
 
dc.relation.referencesReferences in Scopus
 
dc.titleDesign, fabrication and testing of a micro-Venturi tube for fluid manipulation in a microfluidic system
 
dc.typeArticle
 
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Author Affiliations
  1. Case Western Reserve University
  2. Tianjin University