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Article: In vivo three-dimensional spectral domain endoscopic optical coherence tomography using a microelectromechanical system mirror

TitleIn vivo three-dimensional spectral domain endoscopic optical coherence tomography using a microelectromechanical system mirror
Authors
Issue Date2007
PublisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3
Citation
Optics Letters, 2007, v. 32 n. 22, p. 3239-3241 How to Cite?
AbstractA biopsy is a well-known medical test used to evaluate tissue abnormality. Biopsy specimens are invasively taken from part of a lesion and visualized by microscope after chemical treatment. However, diagnosis by means of biopsy is not only variable due to depth and location of specimen but may also damage the specimen. In addition, only a limited number of specimens can be obtained, thus, the entire tissue morphology cannot be observed. We introduce a three-dimensional (3-D) endoscopic optical biopsy via optical coherence tomography employing a dual-axis microelectromechanical system scanning mirror. Since this technique provides high-resolution, noninvasive, direct, and multiple visualization of tissue, it could function as a clinical biopsy with advanced performance. The device was integrated with a conventional endoscope and utilized to generate in vivo 3-D clinical images in humans and animals. © 2007 Optical Society of America.
Persistent Identifierhttp://hdl.handle.net/10722/148954
ISSN
2015 Impact Factor: 3.04
2015 SCImago Journal Rankings: 2.397
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorJung, Wen_HK
dc.contributor.authorMcCormick, DTen_HK
dc.contributor.authorAhn, YCen_HK
dc.contributor.authorSepehr, Aen_HK
dc.contributor.authorBrenner, Men_HK
dc.contributor.authorWong, Ben_HK
dc.contributor.authorTien, NCen_HK
dc.contributor.authorChen, Zen_HK
dc.date.accessioned2012-06-20T06:17:02Z-
dc.date.available2012-06-20T06:17:02Z-
dc.date.issued2007en_HK
dc.identifier.citationOptics Letters, 2007, v. 32 n. 22, p. 3239-3241en_HK
dc.identifier.issn0146-9592en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148954-
dc.description.abstractA biopsy is a well-known medical test used to evaluate tissue abnormality. Biopsy specimens are invasively taken from part of a lesion and visualized by microscope after chemical treatment. However, diagnosis by means of biopsy is not only variable due to depth and location of specimen but may also damage the specimen. In addition, only a limited number of specimens can be obtained, thus, the entire tissue morphology cannot be observed. We introduce a three-dimensional (3-D) endoscopic optical biopsy via optical coherence tomography employing a dual-axis microelectromechanical system scanning mirror. Since this technique provides high-resolution, noninvasive, direct, and multiple visualization of tissue, it could function as a clinical biopsy with advanced performance. The device was integrated with a conventional endoscope and utilized to generate in vivo 3-D clinical images in humans and animals. © 2007 Optical Society of America.en_HK
dc.languageengen_US
dc.publisherOptical Society of America. The Journal's web site is located at http://www.opticsinfobase.org/current.cfm?journal=3en_HK
dc.relation.ispartofOptics Lettersen_HK
dc.subject.meshAnimalsen_US
dc.subject.meshArtifactsen_US
dc.subject.meshBiopsyen_US
dc.subject.meshElectrochemistry - Instrumentation - Methodsen_US
dc.subject.meshEndoscopesen_US
dc.subject.meshEndoscopy - Methodsen_US
dc.subject.meshEquipment Designen_US
dc.subject.meshHumansen_US
dc.subject.meshImage Processing, Computer-Assisted - Methodsen_US
dc.subject.meshImaging, Three-Dimensionalen_US
dc.subject.meshOptics And Photonicsen_US
dc.subject.meshRabbitsen_US
dc.subject.meshTomography, Optical Coherence - Instrumentation - Methodsen_US
dc.titleIn vivo three-dimensional spectral domain endoscopic optical coherence tomography using a microelectromechanical system mirroren_HK
dc.typeArticleen_HK
dc.identifier.emailTien, NC: nctien@hku.hken_HK
dc.identifier.authorityTien, NC=rp01604en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1364/OL.32.003239en_HK
dc.identifier.pmid18026266en_US
dc.identifier.scopuseid_2-s2.0-40149104422en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-40149104422&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume32en_HK
dc.identifier.issue22en_HK
dc.identifier.spage3239en_HK
dc.identifier.epage3241en_HK
dc.identifier.isiWOS:000251747600005-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridJung, W=7201622408en_HK
dc.identifier.scopusauthoridMcCormick, DT=7202521902en_HK
dc.identifier.scopusauthoridAhn, YC=8917906700en_HK
dc.identifier.scopusauthoridSepehr, A=12786684400en_HK
dc.identifier.scopusauthoridBrenner, M=35499949400en_HK
dc.identifier.scopusauthoridWong, B=13105251600en_HK
dc.identifier.scopusauthoridTien, NC=7006532826en_HK
dc.identifier.scopusauthoridChen, Z=7409482950en_HK

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