File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Effects of passive immunization with antisomatostatin serum on plasma corticosterone concentrations in young domestic cockerels

TitleEffects of passive immunization with antisomatostatin serum on plasma corticosterone concentrations in young domestic cockerels
Authors
Issue Date1988
PublisherSociety for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.org
Citation
Journal Of Endocrinology, 1988, v. 116 n. 2, p. 179-183 How to Cite?
AbstractYoung cockerels (6-8 weeks old) were injected with serum from sheep immunized against somatostatin-14 (anti-SRIF) or normal sheep serum (NSS). Blood samples were withdrawn periodically for the determination of plasma corticosterone concentration by radioimmunoassay. With frequent (every 10 min) sampling, NSS-treated control animals exhibited increased plasma corticosterone levels, presumably as a stress response to the experimental manipulation. Anti-SRIF stimulated a much greater increase in plasma corticosterone concentrations and a peak response was observed within 10 to 20 min, when the plasma corticosterone level reached more than twice that of the corresponding control value. With less frequent sampling, plasma corticosterone increased with anti-SRIF administration to as much as nine times the corresponding control value, and the peak response occurred much later. Under pentobarbitone anaesthesia, which itself increased basal corticosterone concentrations, anti-SRIF treatment promoted further increases in plasma corticosterone levels although to a smaller magnitude compared with conscious birds. The results suggest that endogenous somatostatin may play a role in the regulation of adrenocortical function in the domestic fowl. The mechanism of response may involve a central component.
Persistent Identifierhttp://hdl.handle.net/10722/148868
ISSN
2015 Impact Factor: 4.498
2015 SCImago Journal Rankings: 1.910
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorCheung, Aen_US
dc.contributor.authorHarvey, Sen_US
dc.contributor.authorHall, TRen_US
dc.contributor.authorLam, SKen_US
dc.contributor.authorSpencer, GSGen_US
dc.date.accessioned2012-06-20T06:15:48Z-
dc.date.available2012-06-20T06:15:48Z-
dc.date.issued1988en_US
dc.identifier.citationJournal Of Endocrinology, 1988, v. 116 n. 2, p. 179-183en_US
dc.identifier.issn0022-0795en_US
dc.identifier.urihttp://hdl.handle.net/10722/148868-
dc.description.abstractYoung cockerels (6-8 weeks old) were injected with serum from sheep immunized against somatostatin-14 (anti-SRIF) or normal sheep serum (NSS). Blood samples were withdrawn periodically for the determination of plasma corticosterone concentration by radioimmunoassay. With frequent (every 10 min) sampling, NSS-treated control animals exhibited increased plasma corticosterone levels, presumably as a stress response to the experimental manipulation. Anti-SRIF stimulated a much greater increase in plasma corticosterone concentrations and a peak response was observed within 10 to 20 min, when the plasma corticosterone level reached more than twice that of the corresponding control value. With less frequent sampling, plasma corticosterone increased with anti-SRIF administration to as much as nine times the corresponding control value, and the peak response occurred much later. Under pentobarbitone anaesthesia, which itself increased basal corticosterone concentrations, anti-SRIF treatment promoted further increases in plasma corticosterone levels although to a smaller magnitude compared with conscious birds. The results suggest that endogenous somatostatin may play a role in the regulation of adrenocortical function in the domestic fowl. The mechanism of response may involve a central component.en_US
dc.languageengen_US
dc.publisherSociety for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.orgen_US
dc.relation.ispartofJournal of Endocrinologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChickens - Blooden_US
dc.subject.meshCorticosterone - Blooden_US
dc.subject.meshImmune Seraen_US
dc.subject.meshImmunization, Passiveen_US
dc.subject.meshMaleen_US
dc.subject.meshPentobarbital - Pharmacologyen_US
dc.subject.meshSomatostatin - Immunology - Physiologyen_US
dc.titleEffects of passive immunization with antisomatostatin serum on plasma corticosterone concentrations in young domestic cockerelsen_US
dc.typeArticleen_US
dc.identifier.emailCheung, A:lmcheung@hkucc.hku.hken_US
dc.identifier.authorityCheung, A=rp00332en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2895158-
dc.identifier.scopuseid_2-s2.0-0023845203en_US
dc.identifier.volume116en_US
dc.identifier.issue2en_US
dc.identifier.spage179en_US
dc.identifier.epage183en_US
dc.identifier.isiWOS:A1988M087600004-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridCheung, A=8323783300en_US
dc.identifier.scopusauthoridHarvey, S=7202020846en_US
dc.identifier.scopusauthoridHall, TR=7402483718en_US
dc.identifier.scopusauthoridLam, SK=7402279789en_US
dc.identifier.scopusauthoridSpencer, GSG=7102966943en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats