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Article: Somatostatin immunoneutralization affects plasma metabolite concentrations in the domestic fowl

TitleSomatostatin immunoneutralization affects plasma metabolite concentrations in the domestic fowl
Authors
Issue Date1986
Citation
Comparative Biochemistry And Physiology - A Physiology, 1986, v. 85 n. 3, p. 489-494 How to Cite?
Abstract1. Young leghorn cockerels were injected with antiserum to somatostatin (anti-SRIF) and plasma glucose, free fatty acids and α-amino nitrogen concentrations determined. 2. Plasma glucose concentrations increased rapidly after anti-SRIF and remained high for up to 2 hr. Two different antisera tested had hyperglycaemic activity. 3. Plasma free fatty acids also increased rapidly after administration of the two different anti-SRIFs, and remained high for about 1 hr. 4. Plasma α-amino nitrogen increased during the first 30 min after anti-SRIF, then declined to levels significantly lower than control by 1–2 hr after injection. 5. Anaesthesia reduced plasma concentrations of glucose and α-amino nitrogen, and also reduced the changes of these metabolites following anti-SRIF. 6. The results show the importance of endogenous somatostatin in the regulation of plasma metabolite concentrations.
Persistent Identifierhttp://hdl.handle.net/10722/148865
ISSN
2000 SCImago Journal Rankings: 0.403
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHall, TRen_US
dc.contributor.authorCheung, Aen_US
dc.contributor.authorHarvey, Sen_US
dc.contributor.authorLam, SK-
dc.contributor.authorSpencer, GSG-
dc.date.accessioned2012-06-20T06:15:47Z-
dc.date.available2012-06-20T06:15:47Z-
dc.date.issued1986en_US
dc.identifier.citationComparative Biochemistry And Physiology - A Physiology, 1986, v. 85 n. 3, p. 489-494en_US
dc.identifier.issn0300-9629en_US
dc.identifier.urihttp://hdl.handle.net/10722/148865-
dc.description.abstract1. Young leghorn cockerels were injected with antiserum to somatostatin (anti-SRIF) and plasma glucose, free fatty acids and α-amino nitrogen concentrations determined. 2. Plasma glucose concentrations increased rapidly after anti-SRIF and remained high for up to 2 hr. Two different antisera tested had hyperglycaemic activity. 3. Plasma free fatty acids also increased rapidly after administration of the two different anti-SRIFs, and remained high for about 1 hr. 4. Plasma α-amino nitrogen increased during the first 30 min after anti-SRIF, then declined to levels significantly lower than control by 1–2 hr after injection. 5. Anaesthesia reduced plasma concentrations of glucose and α-amino nitrogen, and also reduced the changes of these metabolites following anti-SRIF. 6. The results show the importance of endogenous somatostatin in the regulation of plasma metabolite concentrations.-
dc.languageengen_US
dc.relation.ispartofComparative Biochemistry and Physiology - A Physiologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAntigen-Antibody Complexen_US
dc.subject.meshBlood Glucose - Analysisen_US
dc.subject.meshChickensen_US
dc.subject.meshFatty Acids, Nonesterified - Blooden_US
dc.subject.meshImmune Seraen_US
dc.subject.meshKineticsen_US
dc.subject.meshMaleen_US
dc.subject.meshSomatostatin - Blood - Immunologyen_US
dc.titleSomatostatin immunoneutralization affects plasma metabolite concentrations in the domestic fowlen_US
dc.typeArticleen_US
dc.identifier.emailCheung, A:lmcheung@hkucc.hku.hken_US
dc.identifier.authorityCheung, A=rp00332en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/0300-9629(86)90435-4-
dc.identifier.pmid2878778-
dc.identifier.scopuseid_2-s2.0-0022977980en_US
dc.identifier.volume85en_US
dc.identifier.issue3en_US
dc.identifier.spage489en_US
dc.identifier.epage494en_US
dc.identifier.isiWOS:A1986E719700017-
dc.identifier.scopusauthoridHall, TR=7402483718en_US
dc.identifier.scopusauthoridCheung, A=8323783300en_US
dc.identifier.scopusauthoridHarvey, S=7202020846en_US

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