File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Serotoninergic inhibition of LH secretion in the domestic fowl

TitleSerotoninergic inhibition of LH secretion in the domestic fowl
Authors
Issue Date1986
PublisherSociety for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.org
Citation
Journal Of Endocrinology, 1986, v. 110 n. 2, p. 239-244 How to Cite?
AbstractImmature cockerels were injected with drugs known to affect serotoninergic activity. The receptor agonist quipazine as well as pargyline, an inhibitor of serotonin breakdown, both reduced plasma LH concentrations in a time-dependent fashion. The effect of pargyline was also dose-related. The serotonin precursor, tryptophan, reduced plasma LH levels. Tryptophan and pargyline were as effective in pubertal cockerels as in 3-week-old birds. Responses to quipazine were attenuated by the antagonist, methysergide, although another antagonist, cyproheptadine, also reduced plasma LH levels. Serotonin itself had no effect on plasma LH levels. Parachlorophenylalanine, which blocks serotonin synthesis, had no effect on plasma LH by itself, but attenuated the tryptophan-induced inhibition of LH. The data indicate that serotoninergic mechanisms inhibit secretion of LH in domestic fowl. This mechanism probably operates through the central nervous system.
Persistent Identifierhttp://hdl.handle.net/10722/148864
ISSN
2015 Impact Factor: 4.498
2015 SCImago Journal Rankings: 1.910
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorHall, TRen_US
dc.contributor.authorCheung, Aen_US
dc.contributor.authorHarvey, Sen_US
dc.date.accessioned2012-06-20T06:15:45Z-
dc.date.available2012-06-20T06:15:45Z-
dc.date.issued1986en_US
dc.identifier.citationJournal Of Endocrinology, 1986, v. 110 n. 2, p. 239-244en_US
dc.identifier.issn0022-0795en_US
dc.identifier.urihttp://hdl.handle.net/10722/148864-
dc.description.abstractImmature cockerels were injected with drugs known to affect serotoninergic activity. The receptor agonist quipazine as well as pargyline, an inhibitor of serotonin breakdown, both reduced plasma LH concentrations in a time-dependent fashion. The effect of pargyline was also dose-related. The serotonin precursor, tryptophan, reduced plasma LH levels. Tryptophan and pargyline were as effective in pubertal cockerels as in 3-week-old birds. Responses to quipazine were attenuated by the antagonist, methysergide, although another antagonist, cyproheptadine, also reduced plasma LH levels. Serotonin itself had no effect on plasma LH levels. Parachlorophenylalanine, which blocks serotonin synthesis, had no effect on plasma LH by itself, but attenuated the tryptophan-induced inhibition of LH. The data indicate that serotoninergic mechanisms inhibit secretion of LH in domestic fowl. This mechanism probably operates through the central nervous system.en_US
dc.languageengen_US
dc.publisherSociety for Endocrinology. The Journal's web site is located at http://joe.endocrinology-journals.orgen_US
dc.relation.ispartofJournal of Endocrinologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshChickensen_US
dc.subject.meshCyproheptadine - Pharmacologyen_US
dc.subject.meshFenclonine - Pharmacologyen_US
dc.subject.meshLuteinizing Hormone - Blood - Secretionen_US
dc.subject.meshMaleen_US
dc.subject.meshMethysergide - Pharmacologyen_US
dc.subject.meshPargyline - Pharmacologyen_US
dc.subject.meshQuipazine - Pharmacologyen_US
dc.subject.meshSerotonin - Physiologyen_US
dc.subject.meshTryptophan - Pharmacologyen_US
dc.titleSerotoninergic inhibition of LH secretion in the domestic fowlen_US
dc.typeArticleen_US
dc.identifier.emailCheung, A:lmcheung@hkucc.hku.hken_US
dc.identifier.authorityCheung, A=rp00332en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid2943849-
dc.identifier.scopuseid_2-s2.0-0022512598en_US
dc.identifier.volume110en_US
dc.identifier.issue2en_US
dc.identifier.spage239en_US
dc.identifier.epage244en_US
dc.identifier.isiWOS:A1986D585900008-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridHall, TR=7402483718en_US
dc.identifier.scopusauthoridCheung, A=8323783300en_US
dc.identifier.scopusauthoridharvey, S=7202020846en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats