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Article: Anatomical pathology is dead? Long live anatomical pathology

TitleAnatomical pathology is dead? Long live anatomical pathology
Authors
Issue Date2011
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.asp
Citation
Pathology, 2011, v. 43 n. 6, p. 635-641 How to Cite?
AbstractThe standard diagnostic instrument used for over 150 years by anatomical pathologists has been the optical microscope and glass slide. The advent of immunohistochemistry in the routine laboratory in the 1980s, followed by in situ hybridisation in the 1990s, has increased the armamentaria available to the diagnostic pathologist, and this technology has led to changed patient management in a limited number of neoplastic diseases. The first decade of the 21 st century has seen an increasing number of publications using proteomic technologies that promise to change disease diagnosis and management, the traditional role of an anatomical pathologist. Despite the plethora of publications on proteomics and pathology, to date there are actually limited data where proteomic technologies do appear to be of greater diagnostic value than the standard histological slide. Though proteomic techniques will become more prevalent in the future, it will need the expertise of an anatomical pathologist to dissect out and validate this added information. © 2011 Royal College of Pathologists of Australasia.
Persistent Identifierhttp://hdl.handle.net/10722/148669
ISSN
2015 Impact Factor: 2.968
2015 SCImago Journal Rankings: 1.049
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorNicholls, JMen_US
dc.contributor.authorFrancis, GDen_US
dc.date.accessioned2012-05-29T06:14:33Z-
dc.date.available2012-05-29T06:14:33Z-
dc.date.issued2011en_US
dc.identifier.citationPathology, 2011, v. 43 n. 6, p. 635-641en_US
dc.identifier.issn0031-3025en_US
dc.identifier.urihttp://hdl.handle.net/10722/148669-
dc.description.abstractThe standard diagnostic instrument used for over 150 years by anatomical pathologists has been the optical microscope and glass slide. The advent of immunohistochemistry in the routine laboratory in the 1980s, followed by in situ hybridisation in the 1990s, has increased the armamentaria available to the diagnostic pathologist, and this technology has led to changed patient management in a limited number of neoplastic diseases. The first decade of the 21 st century has seen an increasing number of publications using proteomic technologies that promise to change disease diagnosis and management, the traditional role of an anatomical pathologist. Despite the plethora of publications on proteomics and pathology, to date there are actually limited data where proteomic technologies do appear to be of greater diagnostic value than the standard histological slide. Though proteomic techniques will become more prevalent in the future, it will need the expertise of an anatomical pathologist to dissect out and validate this added information. © 2011 Royal College of Pathologists of Australasia.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.aspen_US
dc.relation.ispartofPathologyen_US
dc.subject.meshAnatomy - Methodsen_US
dc.subject.meshBreast Neoplasms - Chemistry - Diagnosis - Metabolismen_US
dc.subject.meshDiagnosisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshNeoplasms - Chemistry - Diagnosis - Metabolismen_US
dc.subject.meshPathology - Methodsen_US
dc.subject.meshProteomicsen_US
dc.subject.meshTumor Markers, Biological - Analysis - Metabolismen_US
dc.titleAnatomical pathology is dead? Long live anatomical pathologyen_US
dc.typeArticleen_US
dc.identifier.emailNicholls, JM:nicholls@pathology.hku.hken_US
dc.identifier.authorityNicholls, JM=rp00364en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/PAT.0b013e32834a404fen_US
dc.identifier.pmid21876472-
dc.identifier.scopuseid_2-s2.0-83055168503en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-83055168503&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume43en_US
dc.identifier.issue6en_US
dc.identifier.spage635en_US
dc.identifier.epage641en_US
dc.identifier.isiWOS:000295538700011-
dc.publisher.placeUnited Kingdomen_US

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