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Article: Endometrial stromal sarcoma of uterus

TitleEndometrial stromal sarcoma of uterus
Authors
KeywordsEndometrial Stromal Sarcoma
High Grade
Low Grade
Undifferentiated Endometrial Sarcoma
Issue Date2011
PublisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgyn
Citation
Best Practice And Research: Clinical Obstetrics And Gynaecology, 2011, v. 25 n. 6, p. 719-732 How to Cite?
AbstractEndometrial stromal sarcomas are the second most common uterine sarcomas. Currently, they are classified into low-grade endometrial stromal sarcomas and undifferentiated endometrial sarcoma. Low-grade endometrial stromal sarcomas are biologically low-grade uterine sarcomas, and typically composed of uniform cells intimately associated with prominent arterioles, resembling the endometrial stroma in proliferative phase. There is usually little cytological atypia or pleomorphism, and mitoses are scanty. In contrast, undifferentiated endometrial sarcomas are frankly malignant, lack specific differentiation and any features of normal endometrial stroma. It is a highly aggressive neoplasm, often exhibiting myometrial invasion, haemorrhage and necrosis, as well as marked nuclear pleomorphism and high mitotic activity. The diagnosis of undifferentiated endometrial sarcoma is reached after excluding other uterine tumours with a sarcomatous component, such as adenosarcoma and malignant mixed Müllerian tumour. Histological variants of endometrial stromal sarcomas, including the so called 'high-grade endometrial stroma sarcomas' are addressed. The problems with histologic diagnosis and application of immunohistochemical studies and molecular pathology are highlighted. © 2011 Elsevier Ltd. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/148653
ISSN
2015 Impact Factor: 2.291
2015 SCImago Journal Rankings: 1.123
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorXue, WCen_US
dc.contributor.authorCheung, ANYen_US
dc.date.accessioned2012-05-29T06:14:24Z-
dc.date.available2012-05-29T06:14:24Z-
dc.date.issued2011en_US
dc.identifier.citationBest Practice And Research: Clinical Obstetrics And Gynaecology, 2011, v. 25 n. 6, p. 719-732en_US
dc.identifier.issn1521-6934en_US
dc.identifier.urihttp://hdl.handle.net/10722/148653-
dc.description.abstractEndometrial stromal sarcomas are the second most common uterine sarcomas. Currently, they are classified into low-grade endometrial stromal sarcomas and undifferentiated endometrial sarcoma. Low-grade endometrial stromal sarcomas are biologically low-grade uterine sarcomas, and typically composed of uniform cells intimately associated with prominent arterioles, resembling the endometrial stroma in proliferative phase. There is usually little cytological atypia or pleomorphism, and mitoses are scanty. In contrast, undifferentiated endometrial sarcomas are frankly malignant, lack specific differentiation and any features of normal endometrial stroma. It is a highly aggressive neoplasm, often exhibiting myometrial invasion, haemorrhage and necrosis, as well as marked nuclear pleomorphism and high mitotic activity. The diagnosis of undifferentiated endometrial sarcoma is reached after excluding other uterine tumours with a sarcomatous component, such as adenosarcoma and malignant mixed Müllerian tumour. Histological variants of endometrial stromal sarcomas, including the so called 'high-grade endometrial stroma sarcomas' are addressed. The problems with histologic diagnosis and application of immunohistochemical studies and molecular pathology are highlighted. © 2011 Elsevier Ltd. All rights reserved.en_US
dc.languageengen_US
dc.publisherBailliere Tindall. The Journal's web site is located at http://www.elsevier.com/locate/bpobgynen_US
dc.relation.ispartofBest Practice and Research: Clinical Obstetrics and Gynaecologyen_US
dc.subjectEndometrial Stromal Sarcomaen_US
dc.subjectHigh Gradeen_US
dc.subjectLow Gradeen_US
dc.subjectUndifferentiated Endometrial Sarcomaen_US
dc.titleEndometrial stromal sarcoma of uterusen_US
dc.typeArticleen_US
dc.identifier.emailCheung, ANY:anycheun@hkucc.hku.hken_US
dc.identifier.authorityCheung, ANY=rp00542en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/j.bpobgyn.2011.07.004en_US
dc.identifier.pmid21820965-
dc.identifier.scopuseid_2-s2.0-80055050901en_US
dc.identifier.hkuros211352-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-80055050901&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume25en_US
dc.identifier.issue6en_US
dc.identifier.spage719en_US
dc.identifier.epage732en_US
dc.identifier.isiWOS:000297390600005-
dc.publisher.placeUnited Kingdomen_US

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