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Article: Chemical pathology case conference - Renal function tests

TitleChemical pathology case conference - Renal function tests
Authors
Issue Date2006
PublisherHong Kong College of Family Physicians. The Journal's web site is located at http://www.hkcfp.org.hk/
Citation
Hong Kong Practitioner, 2006, v. 28 n. 3, p. 115-122 How to Cite?
AbstractGlomerular filtration rate (GFR) is the best index for assessing the overall renal function but it can only be determined indirectly. Measurement of serum creatinine is the simplest and the most widely used method for GFR assessment. Correct interpretation of serum creatinine levels requires knowledge about the age, sex, muscle mass and physiological states of individual patients and factors that may interfere with laboratory measurements. Determination of creatinine clearance (CrCl) using 24-hour urine sample is also used for GFR assessment. CrCl can overestimate GFR because of the renal tubular secretion of creatinine. Under or over collection of 24-hour urine can cause significant errors in CrCl calculations. The Cockcroft & Gault formula and the abbreviated MDRD equation can provide additional information to serum creatinine level alone. Understanding their limitations is required for accurate application of these equations in clinical practice. Numerous disease processes and pharmaceutical agents have primary and secondary effects on the kidneys. A stepwise investigative approach is required to delineate the underlying cause of renal impairment. Physical examination, routine laboratory tests and some basic radiological examinations help divide the cause of renal impairment into prerenal, renal and postrenal forms. This information is very useful in guiding appropriate management and further investigations.
Persistent Identifierhttp://hdl.handle.net/10722/148462
ISSN
2015 SCImago Journal Rankings: 0.101
References

 

DC FieldValueLanguage
dc.contributor.authorYuen, YPen_US
dc.contributor.authorTam, Sen_US
dc.contributor.authorChan, AKCen_US
dc.contributor.authorMak, TWLen_US
dc.contributor.authorLam, CWen_US
dc.contributor.authorShek, ACCen_US
dc.contributor.authorChiu, RWKen_US
dc.contributor.authorChan, MHMen_US
dc.contributor.authorTai, MHLen_US
dc.contributor.authorChan, AYWen_US
dc.date.accessioned2012-05-29T06:13:07Z-
dc.date.available2012-05-29T06:13:07Z-
dc.date.issued2006en_US
dc.identifier.citationHong Kong Practitioner, 2006, v. 28 n. 3, p. 115-122en_US
dc.identifier.issn1027-3948en_US
dc.identifier.urihttp://hdl.handle.net/10722/148462-
dc.description.abstractGlomerular filtration rate (GFR) is the best index for assessing the overall renal function but it can only be determined indirectly. Measurement of serum creatinine is the simplest and the most widely used method for GFR assessment. Correct interpretation of serum creatinine levels requires knowledge about the age, sex, muscle mass and physiological states of individual patients and factors that may interfere with laboratory measurements. Determination of creatinine clearance (CrCl) using 24-hour urine sample is also used for GFR assessment. CrCl can overestimate GFR because of the renal tubular secretion of creatinine. Under or over collection of 24-hour urine can cause significant errors in CrCl calculations. The Cockcroft & Gault formula and the abbreviated MDRD equation can provide additional information to serum creatinine level alone. Understanding their limitations is required for accurate application of these equations in clinical practice. Numerous disease processes and pharmaceutical agents have primary and secondary effects on the kidneys. A stepwise investigative approach is required to delineate the underlying cause of renal impairment. Physical examination, routine laboratory tests and some basic radiological examinations help divide the cause of renal impairment into prerenal, renal and postrenal forms. This information is very useful in guiding appropriate management and further investigations.en_US
dc.languageengen_US
dc.publisherHong Kong College of Family Physicians. The Journal's web site is located at http://www.hkcfp.org.hk/en_US
dc.relation.ispartofHong Kong Practitioneren_US
dc.titleChemical pathology case conference - Renal function testsen_US
dc.typeArticleen_US
dc.identifier.emailLam, CW:ching-wanlam@pathology.hku.hken_US
dc.identifier.authorityLam, CW=rp00260en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33646773925en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33646773925&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume28en_US
dc.identifier.issue3en_US
dc.identifier.spage115en_US
dc.identifier.epage122en_US
dc.publisher.placeHong Kongen_US

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