File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Computed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma

TitleComputed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinoma
Authors
KeywordsComputed tomography
Lung cancer
Lymphoepithelioma-like carcinoma
Issue Date2003
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00330/index.htm
Citation
European Radiology, 2003, v. 13 n. 3, p. 522-526 How to Cite?
AbstractOur objectives were to document CT features of advanced primary pulmonary lymphoepithelioma-like carcinoma (LELC) and to determine features that may assist differentiation from other non-small cell lung cancers (NSCLC). Imaging and clinical data of all patients with biopsy-proven pulmonary LELC (n=12) were retrieved from a database of all NSCLC patients over a 2-year period. Twenty-five controls were recruited from other inoperable non-LELC NSCLC patients from the database. Pre-treatment CT scans of the thorax of both study and control patients were reviewed for lobe involved; tumour site, borders and size; and pleural, vascular of pulmonary involvement. Presence of lymphangitis carcinomatosis was noted. Lymph node metastasis was characterised as ipsilateral or contralateral enlarged (>1 cm) mediastinal or hilar nodes, or as peribronchovascular nodal spread. Differences between the two groups were tested using Mann-Whitney rank-sum test. The LELC tumours were significantly larger (45.67 vs 17.71 cm 2) than controls and were closely associated with the mediastinum. There were more LELC tumours with well-defined borders (p<0.001) and fewer with spiculated borders (p<0001) than non-LELC tumours. There was increased peribronchovascular nodal spread (p=0.01) and vascular encasement (p=0.02) in LELC compared with non-LELC tumours. Advanced primary pulmonary LELC has distinct radiological features, and can appear as well-defined tumour closely associated with the mediastinum, with peribronchovascular spread and vascular encasement.
Persistent Identifierhttp://hdl.handle.net/10722/148340
ISSN
2015 Impact Factor: 3.64
2015 SCImago Journal Rankings: 2.064
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorOoi, GCen_HK
dc.contributor.authorHo, JCMen_HK
dc.contributor.authorKhong, PLen_HK
dc.contributor.authorWong, MPen_HK
dc.contributor.authorLam, WKen_HK
dc.contributor.authorTsang, KWTen_HK
dc.date.accessioned2012-05-29T06:12:20Z-
dc.date.available2012-05-29T06:12:20Z-
dc.date.issued2003en_HK
dc.identifier.citationEuropean Radiology, 2003, v. 13 n. 3, p. 522-526en_HK
dc.identifier.issn0938-7994en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148340-
dc.description.abstractOur objectives were to document CT features of advanced primary pulmonary lymphoepithelioma-like carcinoma (LELC) and to determine features that may assist differentiation from other non-small cell lung cancers (NSCLC). Imaging and clinical data of all patients with biopsy-proven pulmonary LELC (n=12) were retrieved from a database of all NSCLC patients over a 2-year period. Twenty-five controls were recruited from other inoperable non-LELC NSCLC patients from the database. Pre-treatment CT scans of the thorax of both study and control patients were reviewed for lobe involved; tumour site, borders and size; and pleural, vascular of pulmonary involvement. Presence of lymphangitis carcinomatosis was noted. Lymph node metastasis was characterised as ipsilateral or contralateral enlarged (>1 cm) mediastinal or hilar nodes, or as peribronchovascular nodal spread. Differences between the two groups were tested using Mann-Whitney rank-sum test. The LELC tumours were significantly larger (45.67 vs 17.71 cm 2) than controls and were closely associated with the mediastinum. There were more LELC tumours with well-defined borders (p<0.001) and fewer with spiculated borders (p<0001) than non-LELC tumours. There was increased peribronchovascular nodal spread (p=0.01) and vascular encasement (p=0.02) in LELC compared with non-LELC tumours. Advanced primary pulmonary LELC has distinct radiological features, and can appear as well-defined tumour closely associated with the mediastinum, with peribronchovascular spread and vascular encasement.en_HK
dc.languageengen_US
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00330/index.htmen_HK
dc.relation.ispartofEuropean Radiologyen_HK
dc.subjectComputed tomographyen_HK
dc.subjectLung canceren_HK
dc.subjectLymphoepithelioma-like carcinomaen_HK
dc.subject.meshCarcinoma - pathology - radiography - virology-
dc.subject.meshCarcinoma, Non-Small-Cell Lung - pathology - radiography-
dc.subject.meshEpstein-Barr Virus Infections - complications-
dc.subject.meshLung Neoplasms - pathology - radiography - virology-
dc.subject.meshTomography, X-Ray Computed - methods-
dc.titleComputed tomography characteristics of advanced primary pulmonary lymphoepithelioma-like carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailOoi, GC: cgcooi@hkucc.hku.hken_HK
dc.identifier.emailHo, JCM:jhocm@hku.hken_HK
dc.identifier.emailKhong, PL: plkhong@hkucc.hku.hken_HK
dc.identifier.emailWong, MP: mwpik@hkucc.hku.hk-
dc.identifier.emailLam, WK: lamwk@hku.hk-
dc.identifier.emailTsang, KWT: kwttsang@hku.hk-
dc.identifier.authorityHo, JCM=rp00258en_HK
dc.identifier.authorityKhong, PL=rp00467en_HK
dc.identifier.authorityWong, MP=rp00348en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1007/s00330-002-1535-7-
dc.identifier.pmid12594554-
dc.identifier.scopuseid_2-s2.0-0038343515en_HK
dc.identifier.hkuros81007-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038343515&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume13en_HK
dc.identifier.issue3en_HK
dc.identifier.spage522en_HK
dc.identifier.epage526en_HK
dc.identifier.isiWOS:000181688200011-
dc.publisher.placeGermanyen_HK
dc.identifier.scopusauthoridOoi, GC=7006176119en_HK
dc.identifier.scopusauthoridHo, JCM=7402649981en_HK
dc.identifier.scopusauthoridKhong, PL=7006693233en_HK
dc.identifier.scopusauthoridWong, MP=7403907887en_HK
dc.identifier.scopusauthoridLam, WK=7203021937en_HK
dc.identifier.scopusauthoridTsang, KWT=7201555024en_HK
dc.customcontrol.immutablesml 130620-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats