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Article: Idiopathic myelofibrosis with extramedullary haemopoiesis involving the urinary bladder in a Chinese lady

TitleIdiopathic myelofibrosis with extramedullary haemopoiesis involving the urinary bladder in a Chinese lady
Authors
Issue Date2002
PublisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLH
Citation
Clinical And Laboratory Haematology, 2002, v. 24 n. 1, p. 55-59 How to Cite?
AbstractExtramedullary haemopoiesis (EMH) associated with idiopathic myelofibrosis most commonly involves the reticuloendothelial organs, such as the spleen and liver, although ectopic haemopoietic tissue has also been described rarely in the lymph nodes, skin, gastrointestinal tract, pleura, peritoneum, central nervous system, and genital and urinary tracts. We report on a 54-year-old Chinese lady with a long history of idiopathic myelofibrosis who presented with gross haematuria and left hydronephrosis due to EMH in the bladder trigone. Cystoscopic examination revealed a sessile necrotic papillary growth at the trigone, obstructing the left ureteric orifice. Transurethral resection of the bladder tumour was performed, and microscopic examination of the tumour chips demonstrated atypical megakaryocytes, immature granulocytes and normoblasts, confirming the presence of EMH. The residual bladder tumour responded well to low dose radiotherapy, with subsequent disappearance of haematuria and normalization of ultrasonogram findings.
Persistent Identifierhttp://hdl.handle.net/10722/148268
ISSN
2008 Impact Factor: 1.304
2015 SCImago Journal Rankings: 0.654
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorMak, YKen_US
dc.contributor.authorChan, CHen_US
dc.contributor.authorSo, CCen_US
dc.contributor.authorChan, MKen_US
dc.contributor.authorChu, YCen_US
dc.date.accessioned2012-05-29T06:11:54Z-
dc.date.available2012-05-29T06:11:54Z-
dc.date.issued2002en_US
dc.identifier.citationClinical And Laboratory Haematology, 2002, v. 24 n. 1, p. 55-59en_US
dc.identifier.issn0141-9854en_US
dc.identifier.urihttp://hdl.handle.net/10722/148268-
dc.description.abstractExtramedullary haemopoiesis (EMH) associated with idiopathic myelofibrosis most commonly involves the reticuloendothelial organs, such as the spleen and liver, although ectopic haemopoietic tissue has also been described rarely in the lymph nodes, skin, gastrointestinal tract, pleura, peritoneum, central nervous system, and genital and urinary tracts. We report on a 54-year-old Chinese lady with a long history of idiopathic myelofibrosis who presented with gross haematuria and left hydronephrosis due to EMH in the bladder trigone. Cystoscopic examination revealed a sessile necrotic papillary growth at the trigone, obstructing the left ureteric orifice. Transurethral resection of the bladder tumour was performed, and microscopic examination of the tumour chips demonstrated atypical megakaryocytes, immature granulocytes and normoblasts, confirming the presence of EMH. The residual bladder tumour responded well to low dose radiotherapy, with subsequent disappearance of haematuria and normalization of ultrasonogram findings.en_US
dc.languageengen_US
dc.publisherBlackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLHen_US
dc.relation.ispartofClinical and Laboratory Haematologyen_US
dc.subject.meshCell Lineageen_US
dc.subject.meshFemaleen_US
dc.subject.meshHematopoiesis, Extramedullary - Radiation Effectsen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphocyte Activationen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrimary Myelofibrosis - Etiology - Pathologyen_US
dc.subject.meshUrinary Bladder Neoplasms - Etiology - Pathology - Radiotherapyen_US
dc.titleIdiopathic myelofibrosis with extramedullary haemopoiesis involving the urinary bladder in a Chinese ladyen_US
dc.typeArticleen_US
dc.identifier.emailSo, CC:scc@pathology.hku.hken_US
dc.identifier.authoritySo, CC=rp00391en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1046/j.1365-2257.2002.00424.xen_US
dc.identifier.pmid11843900en_US
dc.identifier.scopuseid_2-s2.0-0036008660en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0036008660&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume24en_US
dc.identifier.issue1en_US
dc.identifier.spage55en_US
dc.identifier.epage59en_US
dc.identifier.isiWOS:000174221900009-
dc.publisher.placeUnited Kingdomen_US

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