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Article: Waldenström macroglobulinemia with karyotypic aberrations involving both homologous 6q

TitleWaldenström macroglobulinemia with karyotypic aberrations involving both homologous 6q
Authors
Issue Date2001
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 2001, v. 124 n. 2, p. 137-139 How to Cite?
AbstractAn 84-year-old female presenting with proptosis and hyperviscosity syndrome was found to have Waldenström macroglobulinemia. Karyotypic analysis showed structural chromosomal abnormalities involving both homologous chromosomes 6 with a deleted 6q at q21-q23 and a complex three-break rearrangement in the t(6;13;21)?(q21;q14;q11). A literature review suggests that deletions of chromosome 6 at 6q21 are associated with lymphoplasmacytoid differentiation and IgM production in B-cell chronic lymphoproliferative disorders. Copyright © 2001 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/148262
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, KFen_US
dc.contributor.authorSo, CCen_US
dc.date.accessioned2012-05-29T06:11:51Z-
dc.date.available2012-05-29T06:11:51Z-
dc.date.issued2001en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 2001, v. 124 n. 2, p. 137-139en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/148262-
dc.description.abstractAn 84-year-old female presenting with proptosis and hyperviscosity syndrome was found to have Waldenström macroglobulinemia. Karyotypic analysis showed structural chromosomal abnormalities involving both homologous chromosomes 6 with a deleted 6q at q21-q23 and a complex three-break rearrangement in the t(6;13;21)?(q21;q14;q11). A literature review suggests that deletions of chromosome 6 at 6q21 are associated with lymphoplasmacytoid differentiation and IgM production in B-cell chronic lymphoproliferative disorders. Copyright © 2001 Elsevier Science Inc.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChromosome Aberrationsen_US
dc.subject.meshChromosomes, Human, Pair 6en_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshWaldenstrom Macroglobulinemia - Blood - Diagnosis - Geneticsen_US
dc.titleWaldenström macroglobulinemia with karyotypic aberrations involving both homologous 6qen_US
dc.typeArticleen_US
dc.identifier.emailSo, CC:scc@pathology.hku.hken_US
dc.identifier.authoritySo, CC=rp00391en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(00)00334-4en_US
dc.identifier.pmid11172905-
dc.identifier.scopuseid_2-s2.0-0035863233en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035863233&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume124en_US
dc.identifier.issue2en_US
dc.identifier.spage137en_US
dc.identifier.epage139en_US
dc.identifier.isiWOS:000167010600009-
dc.publisher.placeUnited Statesen_US

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