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- Publisher Website: 10.1016/S0165-4608(00)00418-0
- Scopus: eid_2-s2.0-0035335790
- PMID: 11408070
- WOS: WOS:000169236100014
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Article: Acute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia?
Title | Acute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia? |
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Authors | |
Issue Date | 2001 |
Publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene |
Citation | Cancer Genetics And Cytogenetics, 2001, v. 127 n. 1, p. 74-76 How to Cite? |
Abstract | The occurrence of trisomy 4 or trisomy 10 as the sole chromosomal abnormality in acute myeloid leukemia (AML) is very rare, the reported frequency being less than 1%. We describe two cases of AML-M2 with concomitant trisomy 4 and trisomy 10, a hitherto undescribed phenomenon. They showed two unusual features, including immunoreactivity for CD56 and a short-lived but rapidly progressive myelodysplastic phase preceding the appearance of frank leukemia. These findings raise the possibility that AML with concommitant trisomy 4 and trisomy 10 may constitute a distinctive subtype of AML. Copyright © 2001 Elsevier Science Inc. |
Persistent Identifier | http://hdl.handle.net/10722/148248 |
ISSN | 2012 Impact Factor: 1.929 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
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dc.contributor.author | Wong, KF | en_US |
dc.contributor.author | So, CC | en_US |
dc.date.accessioned | 2012-05-29T06:11:47Z | - |
dc.date.available | 2012-05-29T06:11:47Z | - |
dc.date.issued | 2001 | en_US |
dc.identifier.citation | Cancer Genetics And Cytogenetics, 2001, v. 127 n. 1, p. 74-76 | en_US |
dc.identifier.issn | 0165-4608 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/148248 | - |
dc.description.abstract | The occurrence of trisomy 4 or trisomy 10 as the sole chromosomal abnormality in acute myeloid leukemia (AML) is very rare, the reported frequency being less than 1%. We describe two cases of AML-M2 with concomitant trisomy 4 and trisomy 10, a hitherto undescribed phenomenon. They showed two unusual features, including immunoreactivity for CD56 and a short-lived but rapidly progressive myelodysplastic phase preceding the appearance of frank leukemia. These findings raise the possibility that AML with concommitant trisomy 4 and trisomy 10 may constitute a distinctive subtype of AML. Copyright © 2001 Elsevier Science Inc. | en_US |
dc.language | eng | en_US |
dc.publisher | Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene | en_US |
dc.relation.ispartof | Cancer Genetics and Cytogenetics | en_US |
dc.subject.mesh | Acute Disease | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Chromosome Banding | en_US |
dc.subject.mesh | Chromosomes, Human, Pair 10 - Genetics | en_US |
dc.subject.mesh | Chromosomes, Human, Pair 4 - Genetics | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | In Situ Hybridization, Fluorescence | en_US |
dc.subject.mesh | Karyotyping | en_US |
dc.subject.mesh | Leukemia, Myeloid - Genetics | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Trisomy | en_US |
dc.title | Acute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia? | en_US |
dc.type | Article | en_US |
dc.identifier.email | So, CC:scc@pathology.hku.hk | en_US |
dc.identifier.authority | So, CC=rp00391 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/S0165-4608(00)00418-0 | en_US |
dc.identifier.pmid | 11408070 | - |
dc.identifier.scopus | eid_2-s2.0-0035335790 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0035335790&selection=ref&src=s&origin=recordpage | en_US |
dc.identifier.volume | 127 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.spage | 74 | en_US |
dc.identifier.epage | 76 | en_US |
dc.identifier.isi | WOS:000169236100014 | - |
dc.publisher.place | United States | en_US |
dc.identifier.issnl | 0165-4608 | - |