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Article: Acute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia?

TitleAcute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia?
Authors
Issue Date2001
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 2001, v. 127 n. 1, p. 74-76 How to Cite?
AbstractThe occurrence of trisomy 4 or trisomy 10 as the sole chromosomal abnormality in acute myeloid leukemia (AML) is very rare, the reported frequency being less than 1%. We describe two cases of AML-M2 with concomitant trisomy 4 and trisomy 10, a hitherto undescribed phenomenon. They showed two unusual features, including immunoreactivity for CD56 and a short-lived but rapidly progressive myelodysplastic phase preceding the appearance of frank leukemia. These findings raise the possibility that AML with concommitant trisomy 4 and trisomy 10 may constitute a distinctive subtype of AML. Copyright © 2001 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/148248
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, KFen_US
dc.contributor.authorSo, CCen_US
dc.date.accessioned2012-05-29T06:11:47Z-
dc.date.available2012-05-29T06:11:47Z-
dc.date.issued2001en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 2001, v. 127 n. 1, p. 74-76en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/148248-
dc.description.abstractThe occurrence of trisomy 4 or trisomy 10 as the sole chromosomal abnormality in acute myeloid leukemia (AML) is very rare, the reported frequency being less than 1%. We describe two cases of AML-M2 with concomitant trisomy 4 and trisomy 10, a hitherto undescribed phenomenon. They showed two unusual features, including immunoreactivity for CD56 and a short-lived but rapidly progressive myelodysplastic phase preceding the appearance of frank leukemia. These findings raise the possibility that AML with concommitant trisomy 4 and trisomy 10 may constitute a distinctive subtype of AML. Copyright © 2001 Elsevier Science Inc.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshChromosome Bandingen_US
dc.subject.meshChromosomes, Human, Pair 10 - Geneticsen_US
dc.subject.meshChromosomes, Human, Pair 4 - Geneticsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIn Situ Hybridization, Fluorescenceen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshLeukemia, Myeloid - Geneticsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTrisomyen_US
dc.titleAcute myeloid leukemia with concomitant trisomies 4 and 10: A distinctive form of myeloid leukemia?en_US
dc.typeArticleen_US
dc.identifier.emailSo, CC:scc@pathology.hku.hken_US
dc.identifier.authoritySo, CC=rp00391en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(00)00418-0en_US
dc.identifier.pmid11408070-
dc.identifier.scopuseid_2-s2.0-0035335790en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0035335790&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume127en_US
dc.identifier.issue1en_US
dc.identifier.spage74en_US
dc.identifier.epage76en_US
dc.identifier.isiWOS:000169236100014-
dc.publisher.placeUnited Statesen_US

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