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Article: Translocation (12;17)(q13;q23) in de novo acute myeloid leukemia with trilineage myelodysplasia

TitleTranslocation (12;17)(q13;q23) in de novo acute myeloid leukemia with trilineage myelodysplasia
Authors
Issue Date1999
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 1999, v. 114 n. 2, p. 159-161 How to Cite?
Abstract12q13 abnormalities have been reported to be associated with a variety of benign and malignant solid tumors. Recently, they have been shown to be a nonrandom karyotypic change in acute myeloid leukemia. We report a case of de novo acute myeloid leukemia with trilineage myelodysplasia showing t(12;17)(q13;q23) as the sole chromosomal abnormality. A review of the literature indicates that 12q13 translocation in acute myeloid leukemia is often associated with concomitant dysmyelopoietic changes. There is also evidence to suggest that 12q13 translocation occurs more frequently in acute myeloid leukemia with a prior history of mutagenic exposure or karyotypic indicators of secondary leukemia. Copyright (C) 1999 Elsevier Science Inc.
Persistent Identifierhttp://hdl.handle.net/10722/148144
ISSN
2012 Impact Factor: 1.929
2013 SCImago Journal Rankings: 0.872
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorWong, KFen_US
dc.contributor.authorSo, CCen_US
dc.contributor.authorYu, PHen_US
dc.date.accessioned2012-05-29T06:11:05Z-
dc.date.available2012-05-29T06:11:05Z-
dc.date.issued1999en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 1999, v. 114 n. 2, p. 159-161en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/148144-
dc.description.abstract12q13 abnormalities have been reported to be associated with a variety of benign and malignant solid tumors. Recently, they have been shown to be a nonrandom karyotypic change in acute myeloid leukemia. We report a case of de novo acute myeloid leukemia with trilineage myelodysplasia showing t(12;17)(q13;q23) as the sole chromosomal abnormality. A review of the literature indicates that 12q13 translocation in acute myeloid leukemia is often associated with concomitant dysmyelopoietic changes. There is also evidence to suggest that 12q13 translocation occurs more frequently in acute myeloid leukemia with a prior history of mutagenic exposure or karyotypic indicators of secondary leukemia. Copyright (C) 1999 Elsevier Science Inc.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshChromosomes, Human, Pair 12 - Geneticsen_US
dc.subject.meshChromosomes, Human, Pair 17 - Geneticsen_US
dc.subject.meshFatal Outcomeen_US
dc.subject.meshHumansen_US
dc.subject.meshKaryotypingen_US
dc.subject.meshLeukemia, Myeloid - Genetics - Pathologyen_US
dc.subject.meshMaleen_US
dc.subject.meshMyelodysplastic Syndromes - Genetics - Pathologyen_US
dc.subject.meshTranslocation, Genetic - Geneticsen_US
dc.titleTranslocation (12;17)(q13;q23) in de novo acute myeloid leukemia with trilineage myelodysplasiaen_US
dc.typeArticleen_US
dc.identifier.emailSo, CC:scc@pathology.hku.hken_US
dc.identifier.authoritySo, CC=rp00391en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(99)00062-Xen_US
dc.identifier.pmid10549276-
dc.identifier.scopuseid_2-s2.0-0032854233en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032854233&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume114en_US
dc.identifier.issue2en_US
dc.identifier.spage159en_US
dc.identifier.epage161en_US
dc.identifier.isiWOS:000083264800015-
dc.publisher.placeUnited Statesen_US

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