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Article: The association between carcinoma of the tonsil and Epstein-Barr virus--a study using radiolabelled in situ hybridization.

TitleThe association between carcinoma of the tonsil and Epstein-Barr virus--a study using radiolabelled in situ hybridization.
Authors
Issue Date1994
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.asp
Citation
Pathology, 1994, v. 26 n. 2, p. 94-98 How to Cite?
AbstractWe reviewed 30 cases of carcinoma of the tonsil and classified them as squamous cell carcinoma, non-keratinizing differentiated carcinoma and non-keratinizing undifferentiated carcinoma. Five cases of non-keratinizing undifferentiated carcinoma were identified, and these, together with 5 cases of squamous cell carcinoma, were studied for the presence of Epstein-Barr virus by in situ hybridization using early RNA (EBERs) as probes. All cases of squamous cell carcinoma were negative for EBER and only one of the 5 cases of non-keratinizing undifferentiated carcinoma was positive. As a positive control we used a case of a primary nasopharyngeal carcinoma with extension to the tonsil. Though the tonsil and nasopharynx share similar anatomical and immunological features, we conclude that in the majority of cases EBV is not demonstrable in tonsillar carcinomas.
Persistent Identifierhttp://hdl.handle.net/10722/148029
ISSN
2015 Impact Factor: 2.968
2015 SCImago Journal Rankings: 1.049
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNicholls, JMen_HK
dc.contributor.authorPittaluga, Sen_HK
dc.contributor.authorChung, LPen_HK
dc.contributor.authorSo, KCen_HK
dc.date.accessioned2012-05-29T06:10:28Z-
dc.date.available2012-05-29T06:10:28Z-
dc.date.issued1994en_HK
dc.identifier.citationPathology, 1994, v. 26 n. 2, p. 94-98en_HK
dc.identifier.issn0031-3025en_HK
dc.identifier.urihttp://hdl.handle.net/10722/148029-
dc.description.abstractWe reviewed 30 cases of carcinoma of the tonsil and classified them as squamous cell carcinoma, non-keratinizing differentiated carcinoma and non-keratinizing undifferentiated carcinoma. Five cases of non-keratinizing undifferentiated carcinoma were identified, and these, together with 5 cases of squamous cell carcinoma, were studied for the presence of Epstein-Barr virus by in situ hybridization using early RNA (EBERs) as probes. All cases of squamous cell carcinoma were negative for EBER and only one of the 5 cases of non-keratinizing undifferentiated carcinoma was positive. As a positive control we used a case of a primary nasopharyngeal carcinoma with extension to the tonsil. Though the tonsil and nasopharynx share similar anatomical and immunological features, we conclude that in the majority of cases EBV is not demonstrable in tonsillar carcinomas.en_HK
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.aspen_HK
dc.relation.ispartofPathologyen_HK
dc.subject.meshCarcinoma - Microbiology - Pathologyen_US
dc.subject.meshCarcinoma, Squamous Cell - Microbiology - Pathologyen_US
dc.subject.meshHerpesvirus 4, Human - Isolation & Purificationen_US
dc.subject.meshHumansen_US
dc.subject.meshIn Situ Hybridizationen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshTonsillar Neoplasms - Microbiology - Pathologyen_US
dc.titleThe association between carcinoma of the tonsil and Epstein-Barr virus--a study using radiolabelled in situ hybridization.en_HK
dc.typeArticleen_HK
dc.identifier.emailNicholls, JM: jmnichol@hkucc.hku.hken_HK
dc.identifier.emailChung, LP: lpchung@hkucc.hku.hken_HK
dc.identifier.authorityNicholls, JM=rp00364en_HK
dc.identifier.authorityChung, LP=rp00249en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8090602-
dc.identifier.scopuseid_2-s2.0-0028419562en_HK
dc.identifier.volume26en_HK
dc.identifier.issue2en_HK
dc.identifier.spage94en_HK
dc.identifier.epage98en_HK
dc.identifier.isiWOS:A1994PK08800003-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridNicholls, JM=7201463077en_HK
dc.identifier.scopusauthoridPittaluga, S=7006897513en_HK
dc.identifier.scopusauthoridChung, LP=24315879100en_HK
dc.identifier.scopusauthoridSo, KC=7102648510en_HK

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