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- Scopus: eid_2-s2.0-0028341463
- PMID: 8039350
- WOS: WOS:A1994NF93100010
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Article: Trisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosis
| Title | Trisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosis |
|---|---|
| Authors | |
| Keywords | karyotypic changes myelodysplasia myelofibrosis |
| Issue Date | 1994 |
| Publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLH |
| Citation | Clinical And Laboratory Haematology, 1994, v. 16 n. 1, p. 79-84 How to Cite? |
| Abstract | We describe a patient with trilineage myelodysplasia and hyperplastic megakaryopoiesis associated with significant myelofibrosis at diagnosis, who developed acute myeloid leukaemia two months afterwards. The clinical and pathological features were consistent with a myelodysplasia/myelofibrosis syndrome with leukemic transformation. Cytogenetic investigation showed trisomy 14, del(20q) and t(3;3) (q21;q26). These findings are of possible significance in the understanding of the association between myelodysplasia and myelofibrosis. |
| Persistent Identifier | http://hdl.handle.net/10722/148024 |
| ISSN | |
| ISI Accession Number ID |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Kwong, YL | en_HK |
| dc.contributor.author | Wan, TSK | en_HK |
| dc.contributor.author | Liang, R | en_HK |
| dc.contributor.author | Chan, LC | en_HK |
| dc.date.accessioned | 2012-05-29T06:10:26Z | - |
| dc.date.available | 2012-05-29T06:10:26Z | - |
| dc.date.issued | 1994 | en_HK |
| dc.identifier.citation | Clinical And Laboratory Haematology, 1994, v. 16 n. 1, p. 79-84 | en_HK |
| dc.identifier.issn | 0141-9854 | en_HK |
| dc.identifier.uri | http://hdl.handle.net/10722/148024 | - |
| dc.description.abstract | We describe a patient with trilineage myelodysplasia and hyperplastic megakaryopoiesis associated with significant myelofibrosis at diagnosis, who developed acute myeloid leukaemia two months afterwards. The clinical and pathological features were consistent with a myelodysplasia/myelofibrosis syndrome with leukemic transformation. Cytogenetic investigation showed trisomy 14, del(20q) and t(3;3) (q21;q26). These findings are of possible significance in the understanding of the association between myelodysplasia and myelofibrosis. | en_HK |
| dc.language | eng | en_US |
| dc.publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/journals/CLH | en_HK |
| dc.relation.ispartof | Clinical and Laboratory Haematology | en_HK |
| dc.subject | karyotypic changes | en_HK |
| dc.subject | myelodysplasia | en_HK |
| dc.subject | myelofibrosis | en_HK |
| dc.subject.mesh | Chromosome Deletion | en_US |
| dc.subject.mesh | Chromosomes, Human, Pair 14 | en_US |
| dc.subject.mesh | Chromosomes, Human, Pair 20 | en_US |
| dc.subject.mesh | Chromosomes, Human, Pair 3 | en_US |
| dc.subject.mesh | Female | en_US |
| dc.subject.mesh | Follow-Up Studies | en_US |
| dc.subject.mesh | Humans | en_US |
| dc.subject.mesh | Karyotyping | en_US |
| dc.subject.mesh | Middle Aged | en_US |
| dc.subject.mesh | Myelodysplastic Syndromes - Genetics | en_US |
| dc.subject.mesh | Primary Myelofibrosis - Genetics | en_US |
| dc.subject.mesh | Translocation, Genetic | en_US |
| dc.subject.mesh | Trisomy | en_US |
| dc.title | Trisomy 14, deletion 20q and t(3;3) (q21;q26) in a case of myelodysplastic syndrome with myelofibrosis | en_HK |
| dc.type | Article | en_HK |
| dc.identifier.email | Kwong, YL:ylkwong@hku.hk | en_HK |
| dc.identifier.email | Liang, R:rliang@hku.hk | en_HK |
| dc.identifier.email | Chan, LC:chanlc@hkucc.hku.hk | en_HK |
| dc.identifier.authority | Kwong, YL=rp00358 | en_HK |
| dc.identifier.authority | Liang, R=rp00345 | en_HK |
| dc.identifier.authority | Chan, LC=rp00373 | en_HK |
| dc.description.nature | link_to_subscribed_fulltext | en_US |
| dc.identifier.pmid | 8039350 | - |
| dc.identifier.scopus | eid_2-s2.0-0028341463 | en_HK |
| dc.identifier.volume | 16 | en_HK |
| dc.identifier.issue | 1 | en_HK |
| dc.identifier.spage | 79 | en_HK |
| dc.identifier.epage | 84 | en_HK |
| dc.identifier.isi | WOS:A1994NF93100010 | - |
| dc.publisher.place | United Kingdom | en_HK |
| dc.identifier.scopusauthorid | Kwong, YL=7102818954 | en_HK |
| dc.identifier.scopusauthorid | Wan, TSK=25623981600 | en_HK |
| dc.identifier.scopusauthorid | Liang, R=26643224900 | en_HK |
| dc.identifier.scopusauthorid | Chan, LC=7403540707 | en_HK |
| dc.identifier.issnl | 0141-9854 | - |
