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- Scopus: eid_2-s2.0-0027970445
- PMID: 7955373
- WOS: WOS:A1994PP74900008
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Article: High-performance thin-layer chromatography of free porphyrins for diagnosis of porphyria
Title | High-performance thin-layer chromatography of free porphyrins for diagnosis of porphyria |
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Authors | |
Issue Date | 1994 |
Publisher | American Association for Clinical Chemistry, Inc. The Journal's web site is located at http://www.clinchem.org |
Citation | Clinical Chemistry, 1994, v. 40 n. 11 I, p. 2026-2029 How to Cite? |
Abstract | In this simple high-performance thin-layer chromatographic technique for evaluating porphyrin excretion, porphyrins rapidly extracted from urine or feces are separated on reversed-phase octadecylsilyl (C18)-bonded silica thin-layer chromatography plates. We observed >12 distinct bands of different porphyrins by viewing the plates under long-wave ultraviolet light. Positive screening tests can readily be characterized by the relative fluorescence of various free porphyrins. The two patients presented in this paper are possibly the first two cases of porphyria cutanea tarda reported in Hong Kong Chinese. |
Persistent Identifier | http://hdl.handle.net/10722/148001 |
ISSN | 2023 Impact Factor: 7.1 2023 SCImago Journal Rankings: 1.460 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Lai, CK | en_US |
dc.contributor.author | Lam, CW | en_US |
dc.contributor.author | Chan, YW | en_US |
dc.date.accessioned | 2012-05-29T06:10:18Z | - |
dc.date.available | 2012-05-29T06:10:18Z | - |
dc.date.issued | 1994 | en_US |
dc.identifier.citation | Clinical Chemistry, 1994, v. 40 n. 11 I, p. 2026-2029 | en_US |
dc.identifier.issn | 0009-9147 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/148001 | - |
dc.description.abstract | In this simple high-performance thin-layer chromatographic technique for evaluating porphyrin excretion, porphyrins rapidly extracted from urine or feces are separated on reversed-phase octadecylsilyl (C18)-bonded silica thin-layer chromatography plates. We observed >12 distinct bands of different porphyrins by viewing the plates under long-wave ultraviolet light. Positive screening tests can readily be characterized by the relative fluorescence of various free porphyrins. The two patients presented in this paper are possibly the first two cases of porphyria cutanea tarda reported in Hong Kong Chinese. | en_US |
dc.language | eng | en_US |
dc.publisher | American Association for Clinical Chemistry, Inc. The Journal's web site is located at http://www.clinchem.org | en_US |
dc.relation.ispartof | Clinical Chemistry | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Chromatography, High Pressure Liquid - Methods | en_US |
dc.subject.mesh | Feces - Chemistry | en_US |
dc.subject.mesh | Hong Kong | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle Aged | en_US |
dc.subject.mesh | Porphyria Cutanea Tarda - Diagnosis | en_US |
dc.subject.mesh | Porphyrins - Analysis - Urine | en_US |
dc.subject.mesh | Ultraviolet Rays | en_US |
dc.title | High-performance thin-layer chromatography of free porphyrins for diagnosis of porphyria | en_US |
dc.type | Article | en_US |
dc.identifier.email | Lam, CW:ching-wanlam@pathology.hku.hk | en_US |
dc.identifier.authority | Lam, CW=rp00260 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.pmid | 7955373 | en_US |
dc.identifier.scopus | eid_2-s2.0-0027970445 | en_US |
dc.identifier.volume | 40 | en_US |
dc.identifier.issue | 11 I | en_US |
dc.identifier.spage | 2026 | en_US |
dc.identifier.epage | 2029 | en_US |
dc.identifier.isi | WOS:A1994PP74900008 | - |
dc.publisher.place | United States | en_US |
dc.identifier.issnl | 0009-9147 | - |