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Article: Adult polycystic kidney disease in Hong Kong Chinese: An autopsy study

TitleAdult polycystic kidney disease in Hong Kong Chinese: An autopsy study
Authors
Issue Date1993
PublisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.asp
Citation
Pathology, 1993, v. 25 n. 3, p. 229-232 How to Cite?
AbstractTo appraise the frequency, clinical features and prognosis of adult polycystic kidney disease (APKD) in Hong Kong, 41 Chinese patients who had an autopsy diagnosis of APKD were studied retrospectively. The APKD patients constituted 0.295% of 13,890 (or one in 339) autopsies performed during the study period (1964-1991). The frequency of APKD in autopsied populations in Western countries varies from one in 261 to one in 1,019 with an average of one in 503. Nineteen (46%) patients reached end-stage renal disease (ESRD) at the time of death. Ruptured berry aneurysm caused death in 3 patients while 3 others had spontaneous intracerebral hemorrhage. Left ventricular hypertrophy was found in 24 (59%) patients. Polycystic liver was present in 26 (63%) patients. This frequency was higher than the 4% to 60% (average 47%) reported in similar studies conducted in Western countries. The probability of patients being alive and without ESRD, estimated using a life table analysis, was 83%, 54%, 32% and 12% by the age of 40, 50, 60 and 70 respectively. No difference in frequency, clinical features and survival between male and female APKD patients could be demonstrated.
Persistent Identifierhttp://hdl.handle.net/10722/147996
ISSN
2015 Impact Factor: 2.968
2015 SCImago Journal Rankings: 1.049
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChan, KWen_US
dc.date.accessioned2012-05-29T06:10:17Z-
dc.date.available2012-05-29T06:10:17Z-
dc.date.issued1993en_US
dc.identifier.citationPathology, 1993, v. 25 n. 3, p. 229-232en_US
dc.identifier.issn0031-3025en_US
dc.identifier.urihttp://hdl.handle.net/10722/147996-
dc.description.abstractTo appraise the frequency, clinical features and prognosis of adult polycystic kidney disease (APKD) in Hong Kong, 41 Chinese patients who had an autopsy diagnosis of APKD were studied retrospectively. The APKD patients constituted 0.295% of 13,890 (or one in 339) autopsies performed during the study period (1964-1991). The frequency of APKD in autopsied populations in Western countries varies from one in 261 to one in 1,019 with an average of one in 503. Nineteen (46%) patients reached end-stage renal disease (ESRD) at the time of death. Ruptured berry aneurysm caused death in 3 patients while 3 others had spontaneous intracerebral hemorrhage. Left ventricular hypertrophy was found in 24 (59%) patients. Polycystic liver was present in 26 (63%) patients. This frequency was higher than the 4% to 60% (average 47%) reported in similar studies conducted in Western countries. The probability of patients being alive and without ESRD, estimated using a life table analysis, was 83%, 54%, 32% and 12% by the age of 40, 50, 60 and 70 respectively. No difference in frequency, clinical features and survival between male and female APKD patients could be demonstrated.en_US
dc.languageengen_US
dc.publisherInforma Healthcare. The Journal's web site is located at http://www.tandf.co.uk/journals/titles/00313025.aspen_US
dc.relation.ispartofPathologyen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAged, 80 And Overen_US
dc.subject.meshChilden_US
dc.subject.meshFemaleen_US
dc.subject.meshHong Kong - Epidemiologyen_US
dc.subject.meshHumansen_US
dc.subject.meshHypertrophy, Left Ventricular - Etiology - Mortalityen_US
dc.subject.meshKidney Failure, Chronic - Etiology - Mortalityen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPolycystic Kidney Diseases - Complications - Epidemiology - Pathologyen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshSurvival Rateen_US
dc.titleAdult polycystic kidney disease in Hong Kong Chinese: An autopsy studyen_US
dc.typeArticleen_US
dc.identifier.emailChan, KW:hrmtckw@hku.hken_US
dc.identifier.authorityChan, KW=rp00330en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8265237-
dc.identifier.scopuseid_2-s2.0-0027747031en_US
dc.identifier.volume25en_US
dc.identifier.issue3en_US
dc.identifier.spage229en_US
dc.identifier.epage232en_US
dc.identifier.isiWOS:A1993MW44900003-
dc.publisher.placeUnited Kingdomen_US

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