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Article: Epstein Barr virus in carcinoma of the cervix

TitleEpstein Barr virus in carcinoma of the cervix
Authors
Issue Date1993
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.intjgynpathology.com
Citation
International Journal Of Gynecological Pathology, 1993, v. 12 n. 3, p. 224-227 How to Cite?
AbstractA group of young patients with invasive carcinoma of the cervix and an age-matched control group were investigated for the presence of Epstein Barr virus (EBV) DNA in cervical biopsies using the polymerase chain reaction. The carcinoma group was further analyzed to evaluate possible associations between the presence of EBV and other prognostic parameters, such as stage, lymph node involvement, and histological tumor type. EBV DNA was found in 20 of 40 (50%) of the carcinoma samples and in 20 of 39 (51%) of the cervical tissues in the control group (p > 0.5). No statistically significant relationship could be noted between the presence or absence of EBV DNA and the effects of other prognostic parameters. In comparison with other studies using similar techniques, this study documented a higher percentage of positive EBV cases in both normal and carcinoma cervical samples. In both groups there was a similar number of positive cases. These results suggest that theories on the possible role played by EBV in the pathogenesis of cervical carcinoma may need to be reconsidered.
Persistent Identifierhttp://hdl.handle.net/10722/147959
ISSN
2015 Impact Factor: 1.437
2015 SCImago Journal Rankings: 0.723
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, KYen_US
dc.contributor.authorCollins, RJen_US
dc.contributor.authorSrivastava, Gen_US
dc.contributor.authorPittaluga, Sen_US
dc.contributor.authorCheung, ANYen_US
dc.contributor.authorWong, LCen_US
dc.date.accessioned2012-05-29T06:10:06Z-
dc.date.available2012-05-29T06:10:06Z-
dc.date.issued1993en_US
dc.identifier.citationInternational Journal Of Gynecological Pathology, 1993, v. 12 n. 3, p. 224-227en_US
dc.identifier.issn0277-1691en_US
dc.identifier.urihttp://hdl.handle.net/10722/147959-
dc.description.abstractA group of young patients with invasive carcinoma of the cervix and an age-matched control group were investigated for the presence of Epstein Barr virus (EBV) DNA in cervical biopsies using the polymerase chain reaction. The carcinoma group was further analyzed to evaluate possible associations between the presence of EBV and other prognostic parameters, such as stage, lymph node involvement, and histological tumor type. EBV DNA was found in 20 of 40 (50%) of the carcinoma samples and in 20 of 39 (51%) of the cervical tissues in the control group (p > 0.5). No statistically significant relationship could be noted between the presence or absence of EBV DNA and the effects of other prognostic parameters. In comparison with other studies using similar techniques, this study documented a higher percentage of positive EBV cases in both normal and carcinoma cervical samples. In both groups there was a similar number of positive cases. These results suggest that theories on the possible role played by EBV in the pathogenesis of cervical carcinoma may need to be reconsidered.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.intjgynpathology.comen_US
dc.relation.ispartofInternational Journal of Gynecological Pathologyen_US
dc.subject.meshAdulten_US
dc.subject.meshBase Sequenceen_US
dc.subject.meshBlotting, Southernen_US
dc.subject.meshDna, Viral - Analysisen_US
dc.subject.meshFemaleen_US
dc.subject.meshHerpesvirus 4, Human - Geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshMolecular Sequence Dataen_US
dc.subject.meshPolymerase Chain Reactionen_US
dc.subject.meshPrognosisen_US
dc.subject.meshUterine Cervical Neoplasms - Microbiologyen_US
dc.titleEpstein Barr virus in carcinoma of the cervixen_US
dc.typeArticleen_US
dc.identifier.emailCollins, RJ:rcollins@hkucc.hku.hken_US
dc.identifier.emailSrivastava, G:gopesh@pathology.hku.hken_US
dc.identifier.emailCheung, ANY:anycheun@hkucc.hku.hken_US
dc.identifier.authorityCollins, RJ=rp00251en_US
dc.identifier.authoritySrivastava, G=rp00365en_US
dc.identifier.authorityCheung, ANY=rp00542en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8393845-
dc.identifier.scopuseid_2-s2.0-0027272014en_US
dc.identifier.volume12en_US
dc.identifier.issue3en_US
dc.identifier.spage224en_US
dc.identifier.epage227en_US
dc.identifier.isiWOS:A1993LJ34100004-
dc.publisher.placeUnited Statesen_US

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