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Article: 8;21 translocation and multilineage involvement

Title8;21 translocation and multilineage involvement
Authors
KeywordsAML
FAB classification
t(8
21)
Issue Date1993
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
Citation
American Journal Of Hematology, 1993, v. 43 n. 3, p. 212-216 How to Cite?
AbstractThe translocation (8;21)(q22;q22) is commonly associated with acute myeloid leukemia (AML) M2 according to the French-American-British (FAB) classification. We describe 11 cases of t(8;21) diagnosed by strict FAB criteria. Six cases were diagnosed as AML M2, 3 cases as AML M4, 1 case as refractory anemia with excess of blasts in transformation, and 1 case as Philadelphia chromosome negative chronic myeloid leukemia in acceleration. Translocation (8;21) could thus occur in a wider variety of hematological abnormalities. Accordingly, we propose that t(8;21) may involve different hemopoietic lineages.
Persistent Identifierhttp://hdl.handle.net/10722/147954
ISSN
2015 Impact Factor: 5.0
2015 SCImago Journal Rankings: 1.761
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKwong, YLen_HK
dc.contributor.authorChing, LMen_HK
dc.contributor.authorLiu, HWen_HK
dc.contributor.authorLee, CPen_HK
dc.contributor.authorPollock, Aen_HK
dc.contributor.authorChan, LCen_HK
dc.date.accessioned2012-05-29T06:10:05Z-
dc.date.available2012-05-29T06:10:05Z-
dc.date.issued1993en_HK
dc.identifier.citationAmerican Journal Of Hematology, 1993, v. 43 n. 3, p. 212-216en_HK
dc.identifier.issn0361-8609en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147954-
dc.description.abstractThe translocation (8;21)(q22;q22) is commonly associated with acute myeloid leukemia (AML) M2 according to the French-American-British (FAB) classification. We describe 11 cases of t(8;21) diagnosed by strict FAB criteria. Six cases were diagnosed as AML M2, 3 cases as AML M4, 1 case as refractory anemia with excess of blasts in transformation, and 1 case as Philadelphia chromosome negative chronic myeloid leukemia in acceleration. Translocation (8;21) could thus occur in a wider variety of hematological abnormalities. Accordingly, we propose that t(8;21) may involve different hemopoietic lineages.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105en_HK
dc.relation.ispartofAmerican Journal of Hematologyen_HK
dc.subjectAMLen_HK
dc.subjectFAB classificationen_HK
dc.subjectt(8en_HK
dc.subject21)en_HK
dc.subject.meshAcute Diseaseen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshChilden_US
dc.subject.meshChromosomes, Human, Pair 21en_US
dc.subject.meshChromosomes, Human, Pair 8en_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Myeloid, Acute - Geneticsen_US
dc.subject.meshLeukemia, Myelomonocytic, Acute - Geneticsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshTranslocation, Geneticen_US
dc.title8;21 translocation and multilineage involvementen_HK
dc.typeArticleen_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.emailChan, LC:chanlc@hkucc.hku.hken_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.identifier.authorityChan, LC=rp00373en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8352238-
dc.identifier.scopuseid_2-s2.0-0027221786en_HK
dc.identifier.volume43en_HK
dc.identifier.issue3en_HK
dc.identifier.spage212en_HK
dc.identifier.epage216en_HK
dc.identifier.isiWOS:A1993LE76800009-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.scopusauthoridChing, LM=24293081200en_HK
dc.identifier.scopusauthoridLiu, HW=7409752648en_HK
dc.identifier.scopusauthoridLee, CP=7410149538en_HK
dc.identifier.scopusauthoridPollock, A=7201613838en_HK
dc.identifier.scopusauthoridChan, LC=7403540707en_HK

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