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Article: Effective salvage therapy using all-trans- retinoic acid for relapsed and resistant acute promyelocytic leukemia

TitleEffective salvage therapy using all-trans- retinoic acid for relapsed and resistant acute promyelocytic leukemia
Authors
Keywordsacute promyelocytic leukaemia
all-trans retinoic acid
Issue Date1993
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.anti-cancerdrugs.com
Citation
Anti-Cancer Drugs, 1993, v. 4 n. 3, p. 339-340 How to Cite?
AbstractAll-trans retinoic acid (ATRA) has been shown to be active against acute promyelocytic leukemia (APL). Six patients with APL, either in relapse or resistant to initial chemotherapy were reinduced with ATRA 100 g/m2/day for 6 weeks. Complete remission was achieved in all six of them. Side effects were seen in two of them. ATRA appears to provide a relatively safe and reliable means to induce a complete remission in patients with refractory or relapsed APL.
Persistent Identifierhttp://hdl.handle.net/10722/147950
ISSN
2015 Impact Factor: 2.268
2015 SCImago Journal Rankings: 0.795
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLiang, Ren_HK
dc.contributor.authorChow, WSen_HK
dc.contributor.authorChiu, Een_HK
dc.contributor.authorChan, TKen_HK
dc.contributor.authorLie, Aen_HK
dc.contributor.authorKwong, YLen_HK
dc.contributor.authorChan, LCen_HK
dc.date.accessioned2012-05-29T06:10:04Z-
dc.date.available2012-05-29T06:10:04Z-
dc.date.issued1993en_HK
dc.identifier.citationAnti-Cancer Drugs, 1993, v. 4 n. 3, p. 339-340en_HK
dc.identifier.issn0959-4973en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147950-
dc.description.abstractAll-trans retinoic acid (ATRA) has been shown to be active against acute promyelocytic leukemia (APL). Six patients with APL, either in relapse or resistant to initial chemotherapy were reinduced with ATRA 100 g/m2/day for 6 weeks. Complete remission was achieved in all six of them. Side effects were seen in two of them. ATRA appears to provide a relatively safe and reliable means to induce a complete remission in patients with refractory or relapsed APL.en_HK
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.anti-cancerdrugs.comen_HK
dc.relation.ispartofAnti-Cancer Drugsen_HK
dc.subjectacute promyelocytic leukaemiaen_HK
dc.subjectall-trans retinoic aciden_HK
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshDrug Resistanceen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, Promyelocytic, Acute - Drug Therapyen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshSalvage Therapyen_US
dc.subject.meshTretinoin - Therapeutic Useen_US
dc.titleEffective salvage therapy using all-trans- retinoic acid for relapsed and resistant acute promyelocytic leukemiaen_HK
dc.typeArticleen_HK
dc.identifier.emailLiang, R:rliang@hku.hken_HK
dc.identifier.emailKwong, YL:ylkwong@hku.hken_HK
dc.identifier.emailChan, LC:chanlc@hkucc.hku.hken_HK
dc.identifier.authorityLiang, R=rp00345en_HK
dc.identifier.authorityKwong, YL=rp00358en_HK
dc.identifier.authorityChan, LC=rp00373en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid8358061-
dc.identifier.scopuseid_2-s2.0-0027178157en_HK
dc.identifier.volume4en_HK
dc.identifier.issue3en_HK
dc.identifier.spage339en_HK
dc.identifier.epage340en_HK
dc.identifier.isiWOS:A1993LJ54600008-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridLiang, R=26643224900en_HK
dc.identifier.scopusauthoridChow, WS=7402281153en_HK
dc.identifier.scopusauthoridChiu, E=24827833600en_HK
dc.identifier.scopusauthoridChan, TK=7402687762en_HK
dc.identifier.scopusauthoridLie, A=24284842400en_HK
dc.identifier.scopusauthoridKwong, YL=7102818954en_HK
dc.identifier.scopusauthoridChan, LC=7403540707en_HK

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