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Article: Pathological basis of surgery in the management of postradiotherapy cervical metastasis in nasopharyngeal carcinoma

TitlePathological basis of surgery in the management of postradiotherapy cervical metastasis in nasopharyngeal carcinoma
Authors
Issue Date1992
PublisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.com
Citation
Archives Of Otolaryngology - Head And Neck Surgery, 1992, v. 118 n. 9, p. 923-930 How to Cite?
AbstractRadical neck dissection was performed on 43 patients with nasopharyngeal carcinoma in whom persistent or recurrent cervical metastasis developed after radiotherapy. The pathologic nature of the tumor in the cervical lymph nodes was studied with step serial sectioning of the entire radical neck dissection specimen at 3-mm intervals. In 70% of patients, more tumor-harboring lymph nodes were detected in the specimen when compared with clinical examination. The extensive behavior of the tumor in the cervical metastases was reflected by the presence of extracapsular spread in 70% of the lymph nodes and the existence of isolated clusters of tumor cells in 35% of the specimens studied. Tumor tissue lying in close proximity to the spinal accessory nerve was demonstrated in 27.5% of the specimens, and 72% of the tumor-bearing lymph nodes were located in the posterior triangle. Radical neck dissection is recommended as the salvage procedure for these patients.
Persistent Identifierhttp://hdl.handle.net/10722/147935
ISSN
2014 Impact Factor: 2.327
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWei, WIen_HK
dc.contributor.authorChiu Ming Hoen_HK
dc.contributor.authorWong, MPen_HK
dc.contributor.authorWing Fung Ngen_HK
dc.contributor.authorSai Kit Lauen_HK
dc.contributor.authorKam Hing Lamen_HK
dc.contributor.authorBatsakis, JGen_HK
dc.date.accessioned2012-05-29T06:09:59Z-
dc.date.available2012-05-29T06:09:59Z-
dc.date.issued1992en_HK
dc.identifier.citationArchives Of Otolaryngology - Head And Neck Surgery, 1992, v. 118 n. 9, p. 923-930en_HK
dc.identifier.issn0886-4470en_HK
dc.identifier.urihttp://hdl.handle.net/10722/147935-
dc.description.abstractRadical neck dissection was performed on 43 patients with nasopharyngeal carcinoma in whom persistent or recurrent cervical metastasis developed after radiotherapy. The pathologic nature of the tumor in the cervical lymph nodes was studied with step serial sectioning of the entire radical neck dissection specimen at 3-mm intervals. In 70% of patients, more tumor-harboring lymph nodes were detected in the specimen when compared with clinical examination. The extensive behavior of the tumor in the cervical metastases was reflected by the presence of extracapsular spread in 70% of the lymph nodes and the existence of isolated clusters of tumor cells in 35% of the specimens studied. Tumor tissue lying in close proximity to the spinal accessory nerve was demonstrated in 27.5% of the specimens, and 72% of the tumor-bearing lymph nodes were located in the posterior triangle. Radical neck dissection is recommended as the salvage procedure for these patients.en_HK
dc.languageengen_US
dc.publisherAmerican Medical Association. The Journal's web site is located at http://www.archoto.comen_HK
dc.relation.ispartofArchives of Otolaryngology - Head and Neck Surgeryen_HK
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshFemaleen_US
dc.subject.meshHead And Neck Neoplasms - Prevention & Control - Secondaryen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphatic Metastasis - Pathology - Prevention & Controlen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNasopharyngeal Neoplasms - Radiotherapyen_US
dc.subject.meshNeck Dissectionen_US
dc.subject.meshSalvage Therapyen_US
dc.titlePathological basis of surgery in the management of postradiotherapy cervical metastasis in nasopharyngeal carcinomaen_HK
dc.typeArticleen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailWong, MP: mwpik@hkucc.hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityWong, MP=rp00348en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1503717-
dc.identifier.scopuseid_2-s2.0-0026746288en_HK
dc.identifier.volume118en_HK
dc.identifier.issue9en_HK
dc.identifier.spage923en_HK
dc.identifier.epage930en_HK
dc.identifier.isiWOS:A1992JL62900011-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridChiu Ming Ho=7409955650en_HK
dc.identifier.scopusauthoridWong, MP=7403907887en_HK
dc.identifier.scopusauthoridWing Fung Ng=7409721309en_HK
dc.identifier.scopusauthoridSai Kit Lau=7409597138en_HK
dc.identifier.scopusauthoridKam Hing Lam=7409839457en_HK
dc.identifier.scopusauthoridBatsakis, JG=35397514500en_HK

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