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Article: Extent of nasopharyngeal carcinoma involvement inside the nasopharynx: Lack of prognostic value on local control

TitleExtent of nasopharyngeal carcinoma involvement inside the nasopharynx: Lack of prognostic value on local control
Authors
Issue Date1992
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741
Citation
Cancer, 1992, v. 69 n. 4, p. 854-859 How to Cite?
AbstractA study on the use of fiberscopic examination and multiple biopsy specimens taken from the nasopharynx in the assessment of the extent of nasopharyngeal carcinoma (NPC) involvement inside the nasopharynx found that the involvement often was more extensive than that detected with conventional methods. In the current study, 247 patients with NPC were studied with the use of fiberscopic examination, and multiple biopsy specimens were taken from the superior wall, posterior wall, and lateral wall of the nasopharynx on both sides. It was confirmed that the tumor often involved the nasopharynx extensively. Also, the extent of primary tumor involvement inside the nasopharynx was correlated with the American Joint Committee (AJC) T stage and the degree of paranasopharyngeal extension of the tumor (P = 0.0100 and 0.0009, respectively), as well as with the size of the largest node and the lowest neck level involved by the node in the ipsilateral neck (P = 0.0005 and 0.005, respectively). However, the extent of primary tumor involvement inside the nasopharynx, expressed as either the number of the six standard sites or the number of the AJC subsites that were involved, had no predictive value on the control of the primary tumor (P = 0.3773 and 0.7794, respectively) at a median follow-up time of 27 months. Except when salvage brachytherapy is contemplated for persistent or recurrent NPC, the extent of primary tumor involvement inside the nasopharynx should not be routinely studied.
Persistent Identifierhttp://hdl.handle.net/10722/147908
ISSN
2015 Impact Factor: 5.649
2015 SCImago Journal Rankings: 3.188
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorSham, JSTen_HK
dc.contributor.authorWei, WIen_HK
dc.contributor.authorNicholls, Jen_HK
dc.contributor.authorChan, CWen_HK
dc.contributor.authorChoy, Den_HK
dc.date.accessioned2012-05-29T06:09:51Z-
dc.date.available2012-05-29T06:09:51Z-
dc.date.issued1992en_HK
dc.identifier.citationCancer, 1992, v. 69 n. 4, p. 854-859en_HK
dc.identifier.issn0008-543Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/147908-
dc.description.abstractA study on the use of fiberscopic examination and multiple biopsy specimens taken from the nasopharynx in the assessment of the extent of nasopharyngeal carcinoma (NPC) involvement inside the nasopharynx found that the involvement often was more extensive than that detected with conventional methods. In the current study, 247 patients with NPC were studied with the use of fiberscopic examination, and multiple biopsy specimens were taken from the superior wall, posterior wall, and lateral wall of the nasopharynx on both sides. It was confirmed that the tumor often involved the nasopharynx extensively. Also, the extent of primary tumor involvement inside the nasopharynx was correlated with the American Joint Committee (AJC) T stage and the degree of paranasopharyngeal extension of the tumor (P = 0.0100 and 0.0009, respectively), as well as with the size of the largest node and the lowest neck level involved by the node in the ipsilateral neck (P = 0.0005 and 0.005, respectively). However, the extent of primary tumor involvement inside the nasopharynx, expressed as either the number of the six standard sites or the number of the AJC subsites that were involved, had no predictive value on the control of the primary tumor (P = 0.3773 and 0.7794, respectively) at a median follow-up time of 27 months. Except when salvage brachytherapy is contemplated for persistent or recurrent NPC, the extent of primary tumor involvement inside the nasopharynx should not be routinely studied.en_HK
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/28741en_HK
dc.relation.ispartofCanceren_HK
dc.subject.meshActuarial Analysisen_US
dc.subject.meshEndoscopy - Methodsen_US
dc.subject.meshFiber Optic Technologyen_US
dc.subject.meshHumansen_US
dc.subject.meshLymphatic Metastasisen_US
dc.subject.meshNasopharyngeal Neoplasms - Pathology - Radiotherapyen_US
dc.subject.meshNasopharynx - Pathologyen_US
dc.subject.meshNeoplasm Invasivenessen_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective Studiesen_US
dc.titleExtent of nasopharyngeal carcinoma involvement inside the nasopharynx: Lack of prognostic value on local controlen_HK
dc.typeArticleen_HK
dc.identifier.emailWei, WI: hrmswwi@hku.hken_HK
dc.identifier.emailNicholls, J: nicholls@pathology.hku.hken_HK
dc.identifier.authorityWei, WI=rp00323en_HK
dc.identifier.authorityNicholls, J=rp00364en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1735076-
dc.identifier.scopuseid_2-s2.0-0026500801en_HK
dc.identifier.volume69en_HK
dc.identifier.issue4en_HK
dc.identifier.spage854en_HK
dc.identifier.epage859en_HK
dc.identifier.isiWOS:A1992HC78400002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridSham, JST=7101655565en_HK
dc.identifier.scopusauthoridWei, WI=7403321552en_HK
dc.identifier.scopusauthoridNicholls, J=7201463077en_HK
dc.identifier.scopusauthoridChan, CW=7404813871en_HK
dc.identifier.scopusauthoridChoy, D=7102939127en_HK

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